SE 175

Product Name
SE 175
CAS No.
258278-64-7
Chemical Name
SE 175
Synonyms
SE 175;SE 175 >=97%;NO PRODRUG, SE 175;JDIVRBDMTYQVOK-UHFFFAOYSA-N;S-(4-NITROOXYMETHYLBENZOYL)METHYLTHIOSALICYLATE;2-[[4-[(NITROOXY)METHYL]BENZOYL]THIO]-BENZOIC ACID, METHYL ESTER;Benzoic acid, 2-[[4-[(nitrooxy)methyl]benzoyl]thio]-, methyl ester
CBNumber
CB1732391
Molecular Formula
C16H13NO6S
Formula Weight
347.34
MOL File
258278-64-7.mol
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SE 175 Property

Boiling point:
493.8±45.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF:50.0(Max Conc. mg/mL);143.53(Max Conc. mM)
DMSO:35.0(Max Conc. mg/mL);100.47(Max Conc. mM)
Ethanol:11.0(Max Conc. mg/mL);31.58(Max Conc. mM)
form 
A crystalline solid
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S2189
Product name
SE 175
Purity
≥97%
Packaging
10mg
Price
$187
Updated
2024/03/01
Cayman Chemical
Product number
82340
Product name
SE 175
Purity
≥97%
Packaging
5mg
Price
$59
Updated
2024/03/01
Cayman Chemical
Product number
82340
Product name
SE 175
Purity
≥97%
Packaging
10mg
Price
$108
Updated
2024/03/01
Cayman Chemical
Product number
82340
Product name
SE 175
Purity
≥97%
Packaging
50mg
Price
$448
Updated
2024/03/01
Cayman Chemical
Product number
82340
Product name
SE 175
Purity
≥97%
Packaging
100mg
Price
$783
Updated
2024/03/01
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SE 175 Chemical Properties,Usage,Production

Description

SE 175 is an organic nitrate compound of the same general class as nitroglycerin. These nitrate compounds can act as NO-donors in vivo following reductive transformation of the nitrate group to nitric oxide. The nitroxyacylated thiosalicylates, such as SE 175, were developed in an effort to facilitate this reductive process and accelerate the release of NO. SE 175 is stable in buffer or saline solution. In the intact rat, it stimulates endothelial soluble guanylate cyclase and induces aortic vasorelaxation with an EC50 of 20 μM, which is intermediate in potency between nitroglycerine and isosorbide dinitrate.

SE 175 Preparation Products And Raw materials

Raw materials

Preparation Products

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SE 175 Suppliers

SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
91

258278-64-7, SE 175Related Search:


  • 2-[[4-[(NITROOXY)METHYL]BENZOYL]THIO]-BENZOIC ACID, METHYL ESTER
  • JDIVRBDMTYQVOK-UHFFFAOYSA-N
  • NO PRODRUG, SE 175
  • S-(4-NITROOXYMETHYLBENZOYL)METHYLTHIOSALICYLATE
  • SE 175
  • Benzoic acid, 2-[[4-[(nitrooxy)methyl]benzoyl]thio]-, methyl ester
  • SE 175 >=97%
  • 258278-64-7
  • Substrates by Enzyme
  • Nitric Oxide Synthase/NO Donor
  • BioChemical
  • Biochemicals and Reagents
  • Enzyme Substrates
  • Enzymes, Inhibitors, and Substrates
  • Nitric Oxide DonorsEnzyme Substrates
  • Nitric Oxide Synthase/NO Donor
  • Nitric Oxide and Cell Stress
  • Nitric Oxide Metabolism
  • Substrates by Enzyme