L(-)-Carvone

Description References

Product Name: L(-)-Carvone
CAS No.: 6485-40-1
Chemical Name: L(-)-Carvone
Synonyms: L-CARVONE;(-)-CARVONE;(-)-Carvone;(R)-(-)-CARVONE;CARVOL;Levo-carvone;(?)-Carvone;2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-enone;2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, (R)-;L(-)-Car
CBNumber: CB1733358
Molecular Formula: C10H14O
Formula Weight: 150.22
MOL File: 6485-40-1.mol

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L(-)-Carvone Property

Melting point:: 25°C
alpha: -57 º (neat)
Boiling point:: 227-230 °C (lit.)
Density: 0.959 g/mL at 25 °C (lit.)
vapor density: 5.2 (vs air)
vapor pressure: 0.4 mm Hg ( 20 °C)
refractive index: n20/D 1.498
FEMA: 2249 | CARVONE
Flash point:: 192 °F
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: Chloroform, Methanol
form: Liquid
color: Clear colorless to pale yellow
Odor: at 100.00 %. sweet spearmint herbal minty
Odor Type: minty
optical activity: [α]20/D 61°, neat
Water Solubility: PRACTICALLY INSOLUBLE
Merck: 14,1874
JECFA Number: 380
BRN: 2206714
Dielectric constant: 11.0（22℃）
InChIKey: ULDHMXUKGWMISQ-SECBINFHSA-N
LogP: 2.74 at 20-37℃
CAS DataBase Reference: 6485-40-1(CAS DataBase Reference)
NIST Chemistry Reference: Carvone(6485-40-1)
EPA Substance Registry System: 2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, (5R)- (6485-40-1)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36-24/25
WGK Germany: 2
RTECS: OS8650000
F: 8-10-23
TSCA: Yes
HS Code: 29142900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W224908
Product name: L-Carvone
Purity: natural, 99%, FG
Packaging: 100g
Price: $88.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: W224908
Product name: L-Carvone
Purity: natural, 99%, FG
Packaging: 1kg
Price: $507
Updated: 2024/03/01

Sigma-Aldrich

Product number: W224901
Product name: L-Carvone
Purity: ≥97%, FCC, FG
Packaging: 1kg
Price: $102
Updated: 2024/03/01

Sigma-Aldrich

Product number: W224901
Product name: L-Carvone
Purity: ≥97%, FCC, FG
Packaging: 5kg
Price: $392
Updated: 2024/03/01

Sigma-Aldrich

Product number: 124931
Product name: (R)-(?)-Carvone
Purity: 98%
Packaging: 5ml
Price: $23.1
Updated: 2024/03/01

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L(-)-Carvone Chemical Properties,Usage,Production

Description

L-(-)-Carvone is the principal odor component of spearmint. It is with a refreshingly cool, minty odor and taste. It is used as flavor ingredient in a variety of foods and beverages, as well as in toothpaste and mouthwash. It is used as a fragrance in personal care products. It is intended for use in the manufacture of an area repellent for mosquitoes and biting flies. L-(-)-carvone is also used in agriculture as a sprout inhibitor of potatoes.

References

[1] Charles S Sell, The Chemistry of Fragrances: From Perfumer to Consumer, 2nd Edition, 2006
[2] https://www.epa.gov
[3] K. J. Hartmans, P. Diepenhorst, W. Bakker and L. G. M. Gorris, The use of carvone in agriculture: sprout suppression of potatoes and antifungal activity against potato tuber and other plant diseases, Industrial Crops and Products, 1995, vol. 4, 3-13

Chemical Properties

clear colorless to pale yellow liquid

Chemical Properties

Caravone occurs in different forms. l-Carvone exhibits odor of spearmint, while d-carvone exhibits odor reminiscent of caraway.

Occurrence

R-Carvone is the main substance in spearmint oil, also present in toothpastes; it is the cause of delayed-type allergy resulting in cheilitis, but Hansson et al. also described a case of angioedema of the lips appearing within minutes after contact with toothpaste, with an open test resulting in an immediate and strong reaction to carvone.

Uses

(R)-(-)-Carvone is used in the flavor and food industry such as chewing gum additives. It is used in air freshening products such as in essential oils as well as in aromatherapy and alternative medicine. It is used to prepare carvomenthol, carvomenthone, dihydrocarvone, carveol and limonene. It reacts with lithium dimethylcuprate to place a methyl group trans to the isopropenyl group with good stereoselectivity. It is also used as a mosquito repellent and prevent premature sprouting of potatoes. Further, it is employed as an important starting material for the synthesis of enantiopure (R)-(+)-3-methyl-6-isopropenyl-cyclohept-3-enone-1 and (4S,6R,7R)-trihydroxy-1-octyne derivatives. It is utilized as a vital raw material for the asymmetric total synthesis of natural products. In addition to this, it is used as a chiral starting material.

Definition

ChEBI: A carvone having (R) configuration.

Aroma threshold values

Detection: d-Carvone: 6.7 to 820 ppb; l-carvone: 2.7 to 600 ppb

General Description

(-)-Carvone, a monoterpene ketone which is the main active component of mentha plant species like Mentha spicata. It has antinociceptive activity which is found to be associated with decreased peripheral nerve excitability.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes.

Synthesis

Carvone occurs in the dextro, levo and racemic form; l-carvone can be isolated from the essential oil of spearmint or is commercially synthesized from d-limonene; d-carvone is usually prepared by fractional distillation of oil of caraway, also from dillseed and dillweed oils, but this type differs in odor and flavors.

L(-)-Carvone Preparation Products And Raw materials

Raw materials

Hydrogen Sulfide Spearmint oil Sulfurous Acid (+)-Dipentene

Preparation Products

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L(-)-Carvone Suppliers

Americas 1 Belgium 1 China 282 Europe 3 France 3 Germany 6 India 22 Japan 4 Switzerland 1 United Kingdom 8 United States 35 Global 366

Apin Chemicals Limited (UK)

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Leancare Ltd.

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MOLEKULA Ltd.

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Country: United Kingdom
ProdList: 6140
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CARBONE SCIENTIFIC CO.,LTD

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Email: sales@carbonesci.com
Country: United Kingdom
ProdList: 6666
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Eurolabs Limited

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ProdList: 6309
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Quest International

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ProdList: 99
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Apin Chemicals Ltd.

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ProdList: 6807
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VWR International

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ProdList: 6548
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View Lastest Price from L(-)-Carvone manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: L(-)-Carvone 6485-40-1
Price: US $60.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-05-14

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: L (-) -Carvone 6485-40-1
Price: US $120.00-65.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-29

Shandong Deshang Chemical Co., Ltd.

Product: L(-)-Carvone 6485-40-1
Price: US $10.00-7.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 10 tons
Release date: 2024-06-05

6485-40-1, L(-)-CarvoneRelated Search:

L-carnitine Methylparaben Levodopa METSULFURON METHYL Bensulfuron methyl Methanol Spearmint oil Methyl cellulose Methyl acrylate Levamisole Kresoxim-methyl Carvone,dihydro Calcium levofolinate Levomilnacipran (1R)-(-)-10-Camphorsulfonic acid Levofloxacin Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate L(-)-Carnitine hydrochloride

(L)-(-)-P-MENTHA-6,8-DIEN-2-ONE

L-P-MENTHA-6,8-DIEN-2-ONE

LAEVO-CARVEONE

L(-)-CARVONE

L-CARVONE

L-1-METHYL-4-ISOPROPENYL-6-CYCLOHEXEN-2-ONE

FEMA 2249

(-)-CARVONE

CARVONE, (-)-

CARVOL

1-Methyl-4-isopropenyl-6-cyclohexen-2-one

1'CARVONE

6,8-p-menthadien-2-one

(R)-(-)-CARVONE

(R)-(-)-P-MENTHA-6,8-DIEN-2-ONE

(R)-5-ISOPROPENYL-2-METHYL-2-CYCLOHEXENONE

(R)-(-)-5-ISOPROPHENYL-2-METHYL-2-CYCLOHEXENONE

P-MENTHA-6,8-DIEN-2-ONE

P-MENTHA-6,8-DIENE-2-ONE

4-MENTHA-6,8-DIEN-2ONE

l-p-mentha-1(6),8-dien-2-one

CARVONE (L) FCC

L-CARVONE 97+% FCC

L(-)-Carvone, 99+%

(-)-carvone,l-p-mentha-6,8(9)-dien-2-one;1-methyl-4-isopropenyl-6-cycloxen-2-one,l-carvone

2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, (5R)-

(-)-Carvone, (R)-5-Isopropenyl-2-methyl-2-cyclohexenone, p-Mentha-6,8-dien-2-one, Carvol

(-)-Carvone, (R)-(-)-Carvone, (R)-5-Isopropenyl-2-methyl-2-cyclohexenone, p-Mentha-6,8-dien-2-one, Carvol

(R)-5-Isopropenyl-2-methyl-2-cyclohexenone, Carvol

2,3-Dimethyl-5-isopropylidene-cyclohexanone

(-)-CARVONE WITH GC

CARVON-LINKS

l-p-Mentha-1(6),8-dien-2-on

(5R)-2-Methyl-5-prop-1-en-2-ylcyclohex-2-en-1-one

[R,(-)]-2-Methyl-5-(1-methylvinyl)-2-cyclohexen-1-one

L(-)-Carvone, 99+% 100GR

L(-)-Carvone, 99+% 5GR

(R)-(-)-CARVONE FOR SYNTHESIS

L(-)-Car

2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-enone

Spearmint Herb

2-[N-(benzenesulfonyl)-4-methoxyanilino]-N-(2-fluorophenyl)acetamide

L-carvone 6485-40-1

carvone E:candyli(at)speedgainpharma(dot)com

(-)-p-mentha-8-dien-2-one

(4R)-(-)-Carvone

(r)-(-)-p-mentha-8-dien-2-one

(r)-2-cyclohexen-1-on

(r)-2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one

2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, (R)-

2-methyl-5-(1-methylethenyl)-,(R)-2-Cyclohexen-1-one

l-6,8(9)-p-Menthadien-2-one

Levo-carvone

p-Mentha-6,8-dien-2-one, (R)-(-)-

L-Carvone FCC

(R)-2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-enone

(R)-(-)-Carvone 98%

(R)-(-)-Carvone &gt