2-(DIMETHYLSILYL)PYRIDINE Property

Boiling point:

175-178 °C(Press: 758 Torr)

Density 

0.92

refractive index 

n20/D 1.499

Flash point:

41 °C

storage temp. 

2-8°C

solubility 

soluble in most common organic solvents.

pka

5.40±0.12(Predicted)

CAS DataBase Reference

21032-48-4

Safety

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

36-26

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-(DIMETHYLSILYL)PYRIDINE Chemical Properties,Usage,Production

Physical properties

bp 68–72 °C/20 mm Hg.

Uses

2-Pyridyldimethylsilane is reagent used for metal-catalyzed hydrosilylation of alkynes and alkenes.Presumably because of the presence of catalyst-directing pyridyl group on silicon, 2- pyridyldimethylsilane exhibits greater reactivity in Rh-catalyzed hydrosilylation of alkenes than those of other related hydrosilanes. Moreover, the presence of the basic pyridyl group enables easy product separation and facile catalyst recovery through simple acid/base extraction.

Uses

A useful scaffold for a number of reactions including hydrosilylation, cross-coupling, and olefination.

Preparation

2-Pyridyldimethylsilane can be prepared by reaction of 2-pyridyllithium with chlorodimethylsilane in dry Et2O at ?78°Cunder argon.