Butenafine

ChemicalBook > CAS DataBase List > Butenafine

Product Name: Butenafine
CAS No.: 101828-21-1
Chemical Name: Butenafine
Synonyms: But·Nafine;BUTENAFINE;Butenafine USP/EP/BP;4-tert-Butylbenzylmethyl 1-naphtylmethylamine;(4-tert-butylbenzyl)-methyl-(1-naphthylmethyl)amine;N-methyl-N-(4-methylbenzyl)-N-(1-naphthylmethyl)amine;N-(4-tert-Butylbenzyl)-N-methyl-1-naphthalenemethanamine;n-(p-tert-butylbenzyl)-n-methyl-1-naphthalenemethylamine;1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine;n-methyl-n-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine
CBNumber: CB1742475
Molecular Formula: C23H27N
Formula Weight: 317.47
MOL File: 101828-21-1.mol

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Butenafine Property

Melting point:: 200-202 °C
Boiling point:: 426.1±14.0 °C(Predicted)
Density: 1.032±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 63 mg/mL (198.44 mM);Ethanol: 63 mg/mL (198.44 mM)
pka: 7.87±0.50(Predicted)
Water Solubility: Water: Insoluble
LogP: 6.770 (est)
CAS DataBase Reference: 101828-21-1(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B690338
Product name: Butenafine
Packaging: 10mg
Price: $55
Updated: 2021/12/16

TRC

Product number: B690338
Product name: Butenafine
Packaging: 100mg
Price: $250
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001791
Product name: BUTENAFINE
Purity: 95.00%
Packaging: 100MG
Price: $885.31
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001791
Product name: BUTENAFINE
Purity: 95.00%
Packaging: 500MG
Price: $1127.86
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb134712
Product name: Butenafine
Purity: >99%
Packaging: 1g
Price: $1208.7
Updated: 2021/12/16

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Butenafine Chemical Properties,Usage,Production

Uses

Butenafine (Mentax) is a synthetic benzylamine antifungal agent, related structurally and pharmacologically to terbinafine. It is thought to act by inhibiting the enzyme squalene 2,3-epoxidase, resulting in decreased ergosterol and corresponding increase in squalene, with subsequent cell membrane permeability alteration and cell death. It is active against dermatophytes, yeast, and Sporothrix.

Definition

ChEBI: Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in funga cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.

brand name

Lotrimin (Schering); Mentax (Mylan Bertek).

Butenafine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Butenafine manufacturers

Sigma Audley

Product: Butenafine 101828-21-1
Price: US $35.00-25.00/kg
Min. Order: 1kg
Purity: 99.8%
Supply Ability: 200tons/year
Release date: 2024-03-15

Dideu Industries Group Limited

Product: Butenafine 101828-21-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-19

Zhuozhou Wenxi import and Export Co., Ltd

Product: Butenafine 101828-21-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

101828-21-1, ButenafineRelated Search:

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n-methyl-n-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine

n-(p-tert-butylbenzyl)-n-methyl-1-naphthalenemethylamine

N-methyl-N-(4-methylbenzyl)-N-(1-naphthylmethyl)amine

4-tert-Butylbenzylmethyl 1-naphtylmethylamine

N-(4-tert-Butylbenzyl)-N-methyl-1-naphthalenemethanamine

(4-tert-butylbenzyl)-methyl-(1-naphthylmethyl)amine

BUTENAFINE

1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine

1-NaphthaleneMethanaMine,N-[[4-(1,1-diMethylethyl)phenyl]Methyl]-N-Methyl-

But·Nafine

Butenafine USP/EP/BP

101828-21-1

92-12-0

C23H27N