ChemicalBook > CAS DataBase List > Butenafine
Butenafine
- Product Name
- Butenafine
- CAS No.
- 101828-21-1
- Chemical Name
- Butenafine
- Synonyms
- But·Nafine;BUTENAFINE;Butenafine USP/EP/BP;4-tert-Butylbenzylmethyl 1-naphtylmethylamine;(4-tert-butylbenzyl)-methyl-(1-naphthylmethyl)amine;N-methyl-N-(4-methylbenzyl)-N-(1-naphthylmethyl)amine;N-(4-tert-Butylbenzyl)-N-methyl-1-naphthalenemethanamine;n-(p-tert-butylbenzyl)-n-methyl-1-naphthalenemethylamine;1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine;n-methyl-n-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine
- CBNumber
- CB1742475
- Molecular Formula
- C23H27N
- Formula Weight
- 317.47
- MOL File
- 101828-21-1.mol
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Butenafine Property
- Melting point:
- 200-202 °C
- Boiling point:
- 426.1±14.0 °C(Predicted)
- Density
- 1.032±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 63 mg/mL (198.44 mM);Ethanol: 63 mg/mL (198.44 mM)
- pka
- 7.87±0.50(Predicted)
- Water Solubility
- Water: Insoluble
- LogP
- 6.770 (est)
- CAS DataBase Reference
- 101828-21-1(CAS DataBase Reference)
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N-Bromosuccinimide Price
TRC
- Product number
- B690338
- Product name
- Butenafine
- Packaging
- 10mg
- Price
- $55
- Updated
- 2021/12/16
TRC
- Product number
- B690338
- Product name
- Butenafine
- Packaging
- 100mg
- Price
- $250
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0001791
- Product name
- BUTENAFINE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $885.31
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0001791
- Product name
- BUTENAFINE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $1127.86
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb134712
- Product name
- Butenafine
- Purity
- >99%
- Packaging
- 1g
- Price
- $1208.7
- Updated
- 2021/12/16
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Butenafine Chemical Properties,Usage,Production
Uses
Butenafine (Mentax) is a synthetic benzylamine antifungal agent, related structurally and pharmacologically to terbinafine. It is thought to act by inhibiting the enzyme squalene 2,3-epoxidase, resulting in decreased ergosterol and corresponding increase in squalene, with subsequent cell membrane permeability alteration and cell death. It is active against dermatophytes, yeast, and Sporothrix.
Definition
ChEBI: Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in funga cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.
brand name
Lotrimin (Schering); Mentax (Mylan Bertek).
Butenafine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Butenafine manufacturers
Sigma Audley
- Product
- Butenafine 101828-21-1
- Price
- US $35.00-25.00/kg
- Min. Order
- 1kg
- Purity
- 99.8%
- Supply Ability
- 200tons/year
- Release date
- 2024-03-15
Dideu Industries Group Limited
- Product
- Butenafine 101828-21-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-19
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Butenafine 101828-21-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
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