ChemicalBook > CAS DataBase List > Pranoprofen
Pranoprofen
- Product Name
- Pranoprofen
- CAS No.
- 52549-17-4
- Chemical Name
- Pranoprofen
- Synonyms
- 2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid;Niflan;Y 8004;Cesflan;Oftalar;Pralofen;Praprofen;ranoprofen;PRANOPROFEN;pyranoprofen
- CBNumber
- CB9189564
- Molecular Formula
- C15H13NO3
- Formula Weight
- 255.27
- MOL File
- 52549-17-4.mol
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Pranoprofen Property
- Melting point:
- 182-183°
- Boiling point:
- 398.5°C (rough estimate)
- Density
- 1.1654 (rough estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.27±0.10(Predicted)
- form
- powder
- color
- white to beige
- InChI
- InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)19-13/h2-7,9H,8H2,1H3,(H,17,18)
- InChIKey
- TVQZAMVBTVNYLA-UHFFFAOYSA-N
- SMILES
- C(C1C=CC2OC3=NC=CC=C3CC=2C=1)(C)C(=O)O
- CAS DataBase Reference
- 52549-17-4(CAS DataBase Reference)
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Safety
- RIDADR
- UN 2811 6.1 / PGIII
- RTECS
- DJ3100950
- Toxicity
- LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1423
- Product name
- Pranoprofen
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $40
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- SML1423
- Product name
- Pranoprofen
- Purity
- ≥98% (HPLC)
- Packaging
- 250mg
- Price
- $118
- Updated
- 2025/07/31
TCI Chemical
- Product number
- P2778
- Product name
- Pranoprofen
- Purity
- min. 98.0 %
- Packaging
- 1G
- Price
- $204
- Updated
- 2025/07/31
TCI Chemical
- Product number
- P2778
- Product name
- Pranoprofen
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $610
- Updated
- 2025/07/31
Cayman Chemical
- Product number
- 17875
- Product name
- Pranoprofen
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $32
- Updated
- 2024/03/01
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Pranoprofen Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Originator
Niflan, Yoshitomi ,Japan ,1981
Uses
Pranoprofen is an anti-inflammatory used in ophthalmology.
Definition
ChEBI: Pranoprofen is a pyridochromene.
Manufacturing Process
A mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C.
Therapeutic Function
Analgesic, Antiinflammatory
General Description
Pranoprofen is an arylalkanoic acid and a non-steroidal anti-inflammatory drug.
Biochem/physiol Actions
Pranoprofen is used in eyes to treat chronic allergic conjunctivitis. It is also used as an anti-inflammatory and analgesic drug after strabismus surgery.
Pranoprofen Preparation Products And Raw materials
Raw materials
Preparation Products
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Pranoprofen Suppliers
- Tel
- 0531-68651908; 13276409687
- 469553953@qq.com
- Country
- China
- ProdList
- 38
- Advantage
- 58
- Tel
- 13425589603
- heran_wang@whpt.com.cn
- Country
- China
- ProdList
- 14
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- +86-21-20908456
- Fax
- 021-58180499
- sales@BioChemBest.com
- Country
- China
- ProdList
- 6003
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2809
- Advantage
- 65
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
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- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 15527768836
- 1791901229@qq.com
- Country
- China
- ProdList
- 6950
- Advantage
- 52
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 6387
- Advantage
- 52
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View Lastest Price from Pranoprofen manufacturers
Shaanxi Dideu New Materials Co. Ltd
- Product
- Pranoprofen 52549-17-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-05-15
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- Pranoprofen 52549-17-4
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-20
airuikechemical co., ltd.
- Product
- Pranoprofen 52549-17-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 20 tons
- Release date
- 2024-04-07
52549-17-4, PranoprofenRelated Search:
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Ibuprofen
N,N-dimethylcarbamoylmethyl alpha,2-dimethyl-5H-1-benzopyrano(2,3-b)pyridine-7-acetate
ALFA-METHYL-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER
4-METHOXY-3-METHYLPHENYLACETIC ACID
Pranoprofen
l-Pranoprofen,(S)-(+)-Pranoprofen
(R)-Pranoprofen,(R)-(-)-Pranoprofen,d-Pranoprofen
2-(4-METHOXY-3-METHYLPHENYL)ACETALDEHYDE
ALFA-METHYL-ALFA-CYANO-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER