ChemicalBook > CAS DataBase List > Pranoprofen

Pranoprofen

Product Name
Pranoprofen
CAS No.
52549-17-4
Chemical Name
Pranoprofen
Synonyms
2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid;Niflan;Y 8004;Cesflan;Oftalar;ranoprofen;PRANOPROFEN;pyranoprofen;dl-Pranoprofen;(RS)-Pranoprofen
CBNumber
CB9189564
Molecular Formula
C15H13NO3
Formula Weight
255.27
MOL File
52549-17-4.mol
More
Less

Pranoprofen Property

Melting point:
182-183°
Boiling point:
398.5°C (rough estimate)
Density 
1.1654 (rough estimate)
refractive index 
1.5500 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
4.27±0.10(Predicted)
form 
powder
color 
white to beige
CAS DataBase Reference
52549-17-4(CAS DataBase Reference)
More
Less

Safety

RIDADR 
UN 2811 6.1 / PGIII
RTECS 
DJ3100950
Toxicity
LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1423
Product name
Pranoprofen
Purity
≥98% (HPLC)
Packaging
50mg
Price
$38.9
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1423
Product name
Pranoprofen
Purity
≥98% (HPLC)
Packaging
250mg
Price
$115
Updated
2024/03/01
Cayman Chemical
Product number
17875
Product name
Pranoprofen
Purity
≥98%
Packaging
50mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
17875
Product name
Pranoprofen
Purity
≥98%
Packaging
1g
Price
$359
Updated
2024/03/01
Cayman Chemical
Product number
17875
Product name
Pranoprofen
Purity
≥98%
Packaging
100mg
Price
$61
Updated
2024/03/01
More
Less

Pranoprofen Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Originator

Niflan, Yoshitomi ,Japan ,1981

Uses

Pranoprofen is an anti-inflammatory used in ophthalmology.

Definition

ChEBI: Pranoprofen is a pyridochromene.

Manufacturing Process

A mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C.

Therapeutic Function

Analgesic, Antiinflammatory

General Description

Pranoprofen is an arylalkanoic acid and a non-steroidal anti-inflammatory drug.

Biochem/physiol Actions

Pranoprofen is used in eyes to treat chronic allergic conjunctivitis. It is also used as an anti-inflammatory and analgesic drug after strabismus surgery.

Pranoprofen Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Pranoprofen Suppliers

Canada 1 China 251 Europe 3 Germany 1 India 2 Japan 1 United Kingdom 5 United States 25 Global 289
Jinan Xuanzheng Pharmaceutical Co. LTD
Tel
18610218799
Email
xuanzhengyaoye@126.com
Country
China
ProdList
14
Advantage
58
Shandong Kehui Pharmaceutical Co. LTD
Tel
13276409687
Email
469553953@qq.com
Country
China
ProdList
32
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2882
Advantage
65
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4647
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
Shanghai Zhanshu Chemical Technology Co., Ltd
Tel
+86-21-58589556
Fax
+86-21-58589557
Country
China
ProdList
413
Advantage
55
Wuhan DKY Technology Co.,Ltd.
Tel
27-81302488 18007166089
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
2024
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Wuhan Chemduro Pharm Tech Co. Ltd.
Tel
18040571231/1402788087
Fax
sales@chemduro.com
Country
China
ProdList
1973
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13358
Advantage
58
Liaoning bomei pharmaceutical technology co. LTD.
Tel
24-24524889 18640309171
Fax
+86-24-24524889
Email
236415745@qq.com
Country
China
ProdList
48
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9798
Advantage
50
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8147
Advantage
55
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2989
Advantage
60
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Guangzhou Ciming Biological Technology Co., Ltd.
Tel
020-38082199,29065168,38082986,29878298,29866629,4000192398
Fax
+86 (20)38082986
Country
China
ProdList
831
Advantage
60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7996
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3496
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3868
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Lancrix Chemicals
Tel
86-21-50817262
Fax
86-21-57712035
Email
sales@lancrix.com
Country
China
ProdList
1503
Advantage
55
Shanghai ChengShao Biological Technology Co., Ltd.
Tel
021-61847300 13341622919
Fax
021-61847300
Email
shcss01@163.com
Country
China
ProdList
4809
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2981
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
Shenzhen Simeiquan Biotechnology Co. Ltd
Tel
18126413629 0755-23311925 2355327053
Fax
0755-23311925
Email
abel@ycgmp.com
Country
China
ProdList
5115
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
Shenzhen Sendi Biological Technology Co., Ltd.
Tel
18124570582 TEL：0755-23574479 2355327139
Fax
0755-23229476 QQ: 2355327139
Email
siliao02@yccreate.com
Country
China
ProdList
6120
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-59402396 13419635609
Fax
027-83989310
Email
13419635609@163.com
Country
China
ProdList
1993
Advantage
55
Wuhan Wsem Biological Co., Ltd.
Tel
027-83778876 13667159345
Fax
027-83778876
Email
13667159345@163.com
Country
China
ProdList
1940
Advantage
55
Anhui kuer Bioengineering Co., Ltd
Tel
0551-65171243 13810511747
Email
kuer@kuerhuaxue.com
Country
China
ProdList
2997
Advantage
55
More
Less

View Lastest Price from Pranoprofen manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
Pranoprofen 52549-17-4
Price
US $15.00/kg
Min. Order
1kg
Purity
99.912%
Supply Ability
10ton
Release date
2024-04-25
Guangzhou PI PI BIOTECH INC
Product
Pranoprofen 52549-17-4
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2021-09-17
airuikechemical co., ltd.
Product
Pranoprofen 52549-17-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99.9%
Supply Ability
20 tons
Release date
2024-04-07

52549-17-4, PranoprofenRelated Search:

Centchroman Imidocarb dipropionate Folic acid Propionic acid Nandrolone phenylpropionate 3-(4-Hydroxyphenyl)propionic acid Ethyl 2-(Chlorosulfonyl)acetate 3-Phenylpropionic acid Ascoric Acid Ibuprofen N,N-dimethylcarbamoylmethyl alpha,2-dimethyl-5H-1-benzopyrano(2,3-b)pyridine-7-acetate ALFA-METHYL-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER 4-METHOXY-3-METHYLPHENYLACETIC ACID Pranoprofen l-Pranoprofen,(S)-(+)-Pranoprofen (R)-Pranoprofen,(R)-(-)-Pranoprofen,d-Pranoprofen 2-(4-METHOXY-3-METHYLPHENYL)ACETALDEHYDE ALFA-METHYL-ALFA-CYANO-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER

  • PRANOPROFEN
  • (RS)-Pranoprofen
  • 5H-[1]Benzopyrano[2,3-b]pyridine-7-acetic acid, a-methyl- (9CI)
  • a-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-ylacetic acid
  • dl-Pranoprofen
  • Niflan
  • Y 8004
  • pyranoprofen
  • (S)-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid
  • [S,(+)]-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid
  • (R)-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid
  • [R,(-)]-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid
  • Cesflan
  • α-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-acetic acid
  • 2-(5h-[1]benzopyrano[2,3-b]pyridin-7-yl)propionic acid
  • Oftalar
  • Pranoprofen, >=99%
  • 5H-[1]Benzopyrano[2,3-b]pyridine-7-aceticacid, a-methyl-
  • Pranoprofen-13C-d3
  • Pranoprofen（mixture of isomers）
  • 5H-[1]Benzopyrano[2,3-b]pyridine-7-acetic acid, α-methyl-
  • (2S)-2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid
  • 2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid
  • Pranoprofen USP/EP/BP
  • Pranoprofen (Pyranoprofen)
  • Antipyretic analgesics Pranoprofen
  • ranoprofen
  • 52549-17-4
  • NIFLAN
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • >97%,BR
  • 52549-17-4