Description Preparation Uses
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3-Phenylpropionic acid

Description Preparation Uses
Product Name
3-Phenylpropionic acid
CAS No.
501-52-0
Chemical Name
3-Phenylpropionic acid
Synonyms
HYDROCINNAMIC ACID;3-PHENYLPROPANOIC ACID;BENZENEPROPANOIC ACID;HYDROXYCINNAMIC ACID;Phenylpropanoic acid;Benzenepropionic acid;NSC 9272;LABOTEST-BB LT00014254;3 - styrene acrylic acid;3-Phenyl-n-propionic acid
CBNumber
CB6230832
Molecular Formula
C9H10O2
Formula Weight
150.17
MOL File
501-52-0.mol
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3-Phenylpropionic acid Property

Melting point:
45-48 °C (lit.)
Boiling point:
280 °C (lit.)
Density 
1.071 g/mL at 25 °C (lit.)
vapor pressure 
0.356Pa at 25℃
FEMA 
2889 | 3-PHENYLPROPIONIC ACID
refractive index 
1.5408 (estimate)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
0.6% soluble in water, soluble in alcohol, Propylene glycol, Glycerin and oils
form 
Liquid
pka
4.66(at 25℃)
Specific Gravity
1.071
color 
Clear yellow to yellow-green
Odor
Very faint, warm-balsamic and sweet odor of Coumarin-Vanillin-type
Odor Type
floral
Water Solubility 
Soluble in water
Merck 
14,4784
JECFA Number
646
BRN 
907515
InChIKey
XMIIGOLPHOKFCH-UHFFFAOYSA-N
LogP
1.153 at 25℃
CAS DataBase Reference
501-52-0(CAS DataBase Reference)
NIST Chemistry Reference
3-Phenylpropanoic acid(501-52-0)
EPA Substance Registry System
Hydrocinnamic acid (501-52-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-37/39-26
WGK Germany 
3
RTECS 
DA8600000
TSCA 
Yes
HS Code 
29163900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W288918
Product name
3-Phenylpropionic Acid
Purity
99%, FG
Packaging
100g
Price
$66.6
Updated
2024/03/01
Sigma-Aldrich
Product number
W288918
Product name
3-Phenylpropionic Acid
Purity
99%, FG
Packaging
1kg
Price
$190
Updated
2024/03/01
Sigma-Aldrich
Product number
W288918
Product name
3-Phenylpropionic Acid
Purity
99%, FG
Packaging
10Kg
Price
$1650
Updated
2024/03/01
Sigma-Aldrich
Product number
135232
Product name
Hydrocinnamic acid
Purity
99%
Packaging
5g
Price
$20.3
Updated
2024/03/01
Sigma-Aldrich
Product number
135232
Product name
Hydrocinnamic acid
Purity
99%
Packaging
100g
Price
$57.2
Updated
2024/03/01
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3-Phenylpropionic acid Chemical Properties,Usage,Production

Description

3-Phenylpropionic acid is a carboxylic acid that belongs to the class of phenylpropanoids. Also referred as hydrocinnamic acid, the chemical is a white crystalline solid with a sweet fatty smell of rose musk cinnamon at room temperature. 3-Phenylpropionic acid is soluble in both water and alcohol. It is widely used in food additives, cosmetics, and pharmaceuticals.

Preparation

Hydrogenation of cinnamic acid is used in the preparation of 3-Phenylpropionic acid. Initially, the chemical was prepared by reduction with sodium amalgam in water by electrolysis.

Uses

Food Industry
3-Phenylpropionic acid is utilized in the food industry as a preservative as well as to maintain the original quality of aroma of frozen foods. It is also used for flavoring and restoring original color to food. 3-Phenylpropionic acid is added to shelved foods to prevent microorganisms from deteriorating the food. It also acts as an antioxidant to prolong the life of foodstuff in shelves. 3-Phenylpropionic acid is also used as a food sweetener.
3-Phenylpropionic acid acts as an emulsifier as it can keep water and oil mixtures separated. 3-Phenylpropionic acid can be added in food for technological reasons in wide range such as processing, manufacturing, packaging, treatment, transportation, and storage.
Cosmetics
3-Phenylpropionic acid is used in beautifying products such as bath gels, detergent powders, and fabric softeners as it gives a floral scent. It is also used as a flavour for mouthwashes and toothpastes.

Chemical Properties

white to off-white crystalline mass, powder or crystals and/or chunk

Chemical Properties

3-Phenylpropionic acid has a faint, sweet odor, somewhat balsamic and coumarin-like with a mildly sweet-sour, vanilla-like taste.

Occurrence

Reported found in raspberry, guava fruit, Vitis vinifera L., papaya, strawberry fruit, cinnamon, cassia leaf, cheddar cheese, cocoa, beer, cognac, white wine, red wine, special wine, rose apple, mushroom, cloudberry, Boletus edulis, fresh mango, licorice and labdanum.

Uses

Used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.
Hydrocinnamic acid was used in the synthesis of three medium-chain acyl-Coenzyme A′s i.e. 3-phenylpropionyl-CoA from mixed anhydrides of fatty acids.

Application

3-Phenylpropionic acid is rarely, if ever, used in perfumes, but it finds some use in flavor compositions, mainly as a fixative in Vanilla imitation, in complexes as a sweetener, and in Cheese imitation flavor for its mild pungency and herbaceous character.

Preparation

By reduction of cinnamic acid using sodium amalgam.

Definition

ChEBI: A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group.

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 5599, 1988 DOI: 10.1016/S0040-4039(00)80822-9

General Description

Hydrocinnamic acid forms complexes with uranium(VI) and has been investigated in aqueous solution by attenuated total reflection fourier transform infrared spectroscopy. Hydrocinnamic acids are the major rhizospheric compounds with known growth regulatory activity.

Purification Methods

Crystallise the acid from *benzene, CHCl3 or pet ether (b 40-60o). Dry it in a vacuum. [Beilstein 9 H 508.]

3-Phenylpropionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Phenylpropionic acid Suppliers

Zaoyang Cixiang Medical Technology Co., Ltd
Tel
19871689299
Email
1242417277@qq.com
Country
China
ProdList
52
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58
Hubei Qibu New Material Technology Co., Ltd.
Tel
0715-8890696 18062324989
Email
2284979616@qq.com
Country
China
ProdList
520
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58
Shanghai mayao chemical technology co., ltd.
Tel
021-51068321
Email
my@mychems.com
Country
China
ProdList
59
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58
Hubei Nordina Biotechnology Co., Ltd.
Tel
19371278702
Email
n13164103386@163.com
Country
China
ProdList
2929
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58
Wuhan lenmaike Industrial Co., Ltd.
Tel
027-027-83916065 18062522895
Fax
027-83916065
Email
landmarkorganic@qq.com
Country
China
ProdList
68
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58
Inner Mongolia Yida Chemical Technology Co., Ltd.
Tel
18967392038
Email
67247734@qq.com
Country
China
ProdList
74
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58
Nantong Tianxiang Bioengineering Co., Ltd
Tel
0513-5666452 4006716686
Fax
0513-5666452
Email
475035221@qq.com
Country
China
ProdList
1073
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58
Zaoyang Cixiang Pharmaceutical Technology Co., LTD
Tel
15671321689
Email
info@cixiangyy.com
Country
China
ProdList
21
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58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
4997
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
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View Lastest Price from 3-Phenylpropionic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
3-Phenylpropionic acid 501-52-0
Price
US $75.00-25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-28
Hebei Weibang Biotechnology Co., Ltd
Product
3-Phenylpropionic acid 501-52-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-10-25
Hebei Weibang Biotechnology Co., Ltd
Product
3-Phenylpropionic acid 501-52-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-11-11

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