ChemicalBook > CAS DataBase List > 2,3,5,6-Tetrafluorophenol

2,3,5,6-Tetrafluorophenol

Product Name: 2,3,5,6-Tetrafluorophenol
CAS No.: 769-39-1
Chemical Name: 2,3,5,6-Tetrafluorophenol
Synonyms: Tetrafluorophenol;Tfp-OH;2,3,5,6-Tetrafluorop;2,3,5,6-Tetrafluorphenol;4H-Tetrafluorophenol 98%;2,3,5,6-tetraflourophenol;2,3,5,6-TETRAFLUOROPHENOL;2,3,5,6-Tetrafluorophenol98%;Phenol, 2,3,5,6-tetrafluoro-;4-Hydroxy-1H-perfluorobenzene
CBNumber: CB1744646
Molecular Formula: C6H2F4O
Formula Weight: 166.07
MOL File: 769-39-1.mol

Less

2,3,5,6-Tetrafluorophenol Property

Melting point:: 37-39 °C (lit.)
Boiling point:: 140 °C (lit.)
Density: 1.4445 (estimate)
Flash point:: 175 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 5.46±0.20(Predicted)
form: Crystalline Low Melting Solid
color: White
Water Solubility: Partly miscible with water.
BRN: 1911548
Stability:: Stable. Incompatible with acid chlorides, acid anhydrides, oxidizing agents.
InChI: InChI=1S/C6H2F4O/c7-2-1-3(8)5(10)6(11)4(2)9/h1,11H
InChIKey: PBYIIRLNRCVTMQ-UHFFFAOYSA-N
SMILES: C1(O)=C(F)C(F)=CC(F)=C1F
CAS DataBase Reference: 769-39-1(CAS DataBase Reference)
NIST Chemistry Reference: 2,3,5,6-Tetrafluorophenol(769-39-1)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: UN3261
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 8
PackingGroup: III
HS Code: 29081990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 196789
Product name: 2,3,5,6-Tetrafluorophenol
Purity: 97%
Packaging: 5g
Price: $52.15
Updated: 2025/07/31

Sigma-Aldrich

Product number: 196789
Product name: 2,3,5,6-Tetrafluorophenol
Purity: 97%
Packaging: 25g
Price: $171.95
Updated: 2025/07/31

TCI Chemical

Product number: T1030
Product name: 2,3,5,6-Tetrafluorophenol
Purity: >98.0%(T)
Packaging: 5g
Price: $51
Updated: 2025/07/31

TCI Chemical

Product number: T1030
Product name: 2,3,5,6-Tetrafluorophenol
Purity: >98.0%(T)
Packaging: 25g
Price: $154
Updated: 2025/07/31

TRC

Product number: T292905
Product name: 2,3,5,6-Tetrafluorophenol
Packaging: 5g
Price: $55
Updated: 2021/12/16

Less

2,3,5,6-Tetrafluorophenol Chemical Properties,Usage,Production

Chemical Properties

white solid

Uses

2,3,5,6-Tetrafluorophenol is a reagent in the preparation of polyfluorophenyl ester-terminated homobifunctional cross-linkers to be used in protein conjugation.

Synthesis

50-01-1

54081-33-3

140-10-3

769-39-1

6340-72-3

Chalcone 1d (1.0 g, 3.4 mmol) was added to a 10 mL DMF solution containing guanidine hydrochloride (0.64 g, 6.7 mmol) and sodium hydride (0.32 g, 13.4 mmol). The reaction mixture was stirred at 50 °C for 1.5 h before being cooled to room temperature and subsequently poured into ice water and extracted with ethyl acetate. Undissolved material at the phase boundary was removed by filtration, resulting in the isolation of 2-amino-6-phenyl-5,6-dihydropyrimidin-4(1H)-one (7a, 0.1 g, 16% yield). The 1H NMR data and melting point (255-257 °C; literature value 257.3 °C [19]) of this product were in agreement with those reported in the literature [19]. The extract was washed with water and dried with CaCl2 and concentrated under reduced pressure to remove the solvent, yielding 0.29 g of residue, which was analyzed by NMR and GC/MS.

References

[1] Russian Journal of Organic Chemistry, 2015, vol. 51, # 12, p. 1745 - 1752
[2] Zh. Org. Khim., 2015, vol. 51, # 12, p. 1778 - 1785,8

2,3,5,6-Tetrafluorophenol Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2,3,5,6-Tetrafluorophenol Suppliers

Belgium 1 China 214 Europe 4 France 1 Germany 3 India 6 Italy 1 Japan 3 Jordan 1 Russia 1 Slovakia 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 16 United States 29 Global 285

Qi-Chem Co., Ltd.

Tel: 0411-88165951 13601035838
Fax: 0411-87406949
Email: marketing@qi-chem.com
Country: China
ProdList: 160
Advantage: 58

SHANG FLUORO

Tel: 021-65170832 15601903708
Email: qinba_1@163.com
Country: China
ProdList: 399
Advantage: 60

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Wuhan Wei Shunda Technology Development Co., Ltd.

Tel: 86-027-88774375
Fax: 86-027-88416321
Email: mwmwhot@163.com
Country: China
ProdList: 233
Advantage: 65

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16077
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6134
Advantage: 55

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3930
Advantage: 58

Huainan Kedi Chemical Factory

Tel: 0554-2106669
Fax: 0554-2666215
Email: sales1@kedichem.com
Country: China
ProdList: 4924
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Zhengzhou HongSheng Pharmaceutical Co., Ltd.

Tel: 0371-0371-13526885213 15637198702
Fax: 0371-63709726
Email: hsyykjchem@163.com
Country: China
ProdList: 3852
Advantage: 58

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 6295
Advantage: 60

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9858
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Zhengzhou KeYulong chemical products Co., Ltd

Tel: 17319789407 17319789407
Fax: 0371-53335504
Email: Keyulongchem@163.com
Country: China
ProdList: 1987
Advantage: 55

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6468
Advantage: 55

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: sales@chemwill.com
Country: China
ProdList: 1974
Advantage: 58

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 3495
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Less

View Lastest Price from 2,3,5,6-Tetrafluorophenol manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2,3,5,6-Tetrafluorophenol 769-39-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-07-11

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2,3,5,6-Tetrafluorophenol 769-39-1
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-21

Henan Aochuang Chemical Co.,Ltd.

Product: 2,3,5,6-Tetrafluorophenol 769-39-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-08

769-39-1, 2,3,5,6-TetrafluorophenolRelated Search:

Dimefluthrin 9-FLUORENYLMETHYL PENTAFLUOROPHENYL CARBONATE Pentafluorophenol PENTAFLUOROPHENYL ACRYLATE 2,3,4,5,6-PENTAFLUOROANISOLE FMOC-GLY-OPFP Tetrafluorohydroquinone PENTAFLUOROPHENOXYACETIC ACID PENTAFLUOROPHENYL METHACRYLATE FMOC-ASP(OTBU)-OPFP 2,3,5,6-TETRAFLUOROANISOLE OCTAFLUORO-4,4'-BIPHENOL 2,3,5,6-Tetrafluorophenole potassium salt 4,4'-DIMETHOXYOCTAFLUOROBIPHENYL 2,3,4,5,6-PENTAFLUOROPHENYL 4-METHYLBENZENESULFONATE FMOC-SER(TBU)-OPFP FMOC-CYS(TBU)-OPFP PENTAFLUOROPHENYL ACETATE

2,3,5,6-Tetrafluorop

2,3,5,6-tetrafluoroethane phenol

4-Hydroxy-1H-perfluorobenzene

2,3,5,6-Tetrafluorophenol, 98% 5GR

2,3,5,6-Tetrafluorophenol,tech.

2,3,5,6-Tetrafluorophenol 98%

2,3,5,6-Tetrafluorophenol98%

Tfp-OH (Tetramethylfluoroformamidiniun hexafluorophosphate)

2,3,5,6-Tetrafluorophenol, min. 98%

2,3,5,6-tetraflourophenol

2,3,5,6-Tetrafluorphenol

Tetrafluorophenol

4H-Tetrafluorophenol 98%

2,3,5,6-TETRAFLUOROPHENOL

Phenol, 2,3,5,6-tetrafluoro-

Tfp-OH

Tetrafluorophenolminwhitewaxysolid

2,3,5,6-Tetrafluorophenol, 97+%

2,3,5,6-TETRAFLUOROPHENOL 769-39-1

2,3,5,6-Tetrafluorophenol ISO 9001：2015 REACH

769-39-1

F4C6HOH

HC6F4OH

C6H2F4O

Building Blocks

Oxygen Compounds

Phenols

Organic Building Blocks

pharmacetical

Phenol&Thiophenol&Mercaptan

Organic Building Blocks

Oxygen Compounds

Phenols