2,5-Dimethoxyphenylboronic acid
- Product Name
- 2,5-Dimethoxyphenylboronic acid
- CAS No.
- 107099-99-0
- Chemical Name
- 2,5-Dimethoxyphenylboronic acid
- Synonyms
- AKOS BRN-0036;RARECHEM AH PB 0098;CHEMBRDG-BB 3200971;2,5-Dimethoxyphenylboronic;2,5-Dimethoxyphenylboronicaci;2,5-DIMETHOXYPHENYLBORONIC ACID;2,5-DIMETHOXYBENZENEBORONIC ACID;2,5-Dimethoxyphenylboronic acid,97%;B-(2,5-dimethoxyphenyl)-Boronicacid;2,5-DIMETHOXYPHENYLBORONIC ACID,99+%
- CBNumber
- CB1745380
- Molecular Formula
- C8H11BO4
- Formula Weight
- 181.98
- MOL File
- 107099-99-0.mol
2,5-Dimethoxyphenylboronic acid Property
- Melting point:
- 95-98 °C (lit.)
- Boiling point:
- 374.5±52.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- 8.12±0.58(Predicted)
- form
- solid
- color
- White to Light yellow
- BRN
- 2969872
- InChI
- InChI=1S/C8H11BO4/c1-12-6-3-4-8(13-2)7(5-6)9(10)11/h3-5,10-11H,1-2H3
- InChIKey
- QOZLFNQLIKOGDR-UHFFFAOYSA-N
- SMILES
- B(C1=CC(OC)=CC=C1OC)(O)O
- CAS DataBase Reference
- 107099-99-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 37/39-26-36/37-36/37/39
- WGK Germany
- 3
- Hazard Note
- Irritant/Keep Cold
- HazardClass
- IRRITANT
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 483494
- Product name
- 2,5-Dimethoxyphenylboronic acid
- Purity
- ≥95%
- Packaging
- 5g
- Price
- $46
- Updated
- 2023/06/20
- Product number
- 483494
- Product name
- 2,5-Dimethoxyphenylboronic acid
- Purity
- ≥95%
- Packaging
- 25g
- Price
- $135
- Updated
- 2023/01/07
- Product number
- D3522
- Product name
- 2,5-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 1g
- Price
- $31
- Updated
- 2025/07/31
- Product number
- D3522
- Product name
- 2,5-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 5g
- Price
- $122
- Updated
- 2025/07/31
- Product number
- D479208
- Product name
- 2,5-Dimethoxyphenylboronic acid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
2,5-Dimethoxyphenylboronic acid Chemical Properties,Usage,Production
Chemical Properties
white to almost white crystalline powder
Uses
suzuki reaction
Uses
2,5-Dimethoxyphenylboronic acid is a bacterial mutagen.
Synthesis
121-43-7
25245-34-5
107099-99-0
In a 1 L round bottom flask, 1-bromo-2,5-dimethoxybenzene (50 g, 230 mmol) was dissolved in tetrahydrofuran (400 ml). After cooling the reaction mixture to -78°C, n-butyllithium (167 ml, 280 mmol) was added slowly and dropwise. The reaction temperature was maintained at -78°C with continuous stirring for 2 hours. Subsequently, trimethyl borate (36 ml, 320 mmol) was added. The reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, acidification was carried out by slow dropwise addition of 2N HCl solution. Extraction was carried out with deionized water and ethyl acetate and the organic layer was separated and dried over anhydrous magnesium sulfate. The dried organic phase was concentrated in vacuum to give the crude product. Finally, the purified 2,5-dimethoxyphenylboronic acid (20.8 g, 50% yield) was obtained by recrystallization from a solvent mixture of heptane and toluene.
References
[1] Patent: US2017/18723, 2017, A1. Location in patent: Paragraph 0157-0158
[2] Patent: US5688808, 1997, A
[3] Patent: US5693646, 1997, A
[4] Patent: US5688810, 1997, A
[5] Patent: US5696127, 1997, A
2,5-Dimethoxyphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2,5-Dimethoxyphenylboronic acid Suppliers
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View Lastest Price from 2,5-Dimethoxyphenylboronic acid manufacturers
- Product
- 2,5-Dimethoxyphenylboronic acid 107099-99-0
- Price
- US $34.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 2,5-Dimethoxyphenylboronic acid 107099-99-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 2,5-Dimethoxyphenylboronic acid 107099-99-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09