4-BROMOOXINDOLE
- Product Name
- 4-BROMOOXINDOLE
- CAS No.
- 99365-48-7
- Chemical Name
- 4-BROMOOXINDOLE
- Synonyms
- 4-Bromoindolin-2-one;4-BROMOOXINDOLE;4-Bromo-2-oxindole;4-BROMO-2-OXYINDOLE;4-Bromooxindole ,98%;4-broMo-1H-indol-1-ol;4-bromo-2H-indol-2-one;4-BroMo-1,3-dihydro-indol-2-one;4-Bromo-1,3-dihydro-2H-indol-2-one;4-Bromo-2,3-dihydro-1H-indol-2-one
- CBNumber
- CB1753046
- Molecular Formula
- C8H6BrNO
- Formula Weight
- 212.04
- MOL File
- 99365-48-7.mol
4-BROMOOXINDOLE Property
- Melting point:
- 202-208
- Boiling point:
- 358.2±42.0 °C(Predicted)
- Density
- 1.666±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 13.24±0.20(Predicted)
- color
- White to Light yellow to Light orange
- InChI
- InChI=1S/C8H6BrNO/c9-6-2-1-3-7-5(6)4-8(11)10-7/h1-3H,4H2,(H,10,11)
- InChIKey
- XQQPPAZTHUEMPF-UHFFFAOYSA-N
- SMILES
- N1C2=C(C(Br)=CC=C2)CC1=O
- CAS DataBase Reference
- 99365-48-7
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-39
- HazardClass
- IRRITANT
- HS Code
- 2933790090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B5903
- Product name
- 4-Bromoindolin-2-one
- Packaging
- 200MG
- Price
- $55
- Updated
- 2025/07/31
- Product number
- B5903
- Product name
- 4-Bromoindolin-2-one
- Packaging
- 1G
- Price
- $186
- Updated
- 2025/07/31
- Product number
- FB46437
- Product name
- 4-Bromo-2-oxyindole
- Packaging
- 500mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- 058624
- Product name
- 4-Bromo-2,3-dihydro-1H-indol-2-one
- Purity
- >95%
- Packaging
- 5g
- Price
- $154
- Updated
- 2021/12/16
- Product number
- FB46437
- Product name
- 4-Bromo-2-oxyindole
- Packaging
- 1g
- Price
- $240
- Updated
- 2021/12/16
4-BROMOOXINDOLE Chemical Properties,Usage,Production
Uses
4-Bromooxindole is a reactant that has been used in the preparation of benzylidene bromo isatin derivatives with antitumor activity.
Synthesis
37777-74-5
99365-48-7
To a stirred solution of 2-(2-bromo-6-nitrophenyl)acetic acid (0.66 g, 2.54 mmol) dissolved in a solvent mixture of 50% H2SO4 (6.0 mL) and EtOH (10.0 mL), zinc powder (0.66 g, 10.1 mmol) was added, and the reaction was carried out at 90 °C in an N2 atmosphere. After completion of the reaction, the reaction mixture was treated according to a similar method as in preparation 5 to give the intermediate 4-bromoindolone (0.50 g, 93% yield). The mass spectrum (electrospray ionization) showed an M+1 peak of 212 and an M+2 peak of 214.
References
[1] Patent: US2003/225127, 2003, A1. Location in patent: Page 16
[2] Chemical and Pharmaceutical Bulletin, 1985, vol. 33, # 4, p. 1414 - 1418
4-BROMOOXINDOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BROMOOXINDOLE manufacturers
- Product
- 4-BROMOOXINDOLE 99365-48-7
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-07
- Product
- 4-BROMOOXINDOLE 99365-48-7
- Price
- US $36.00-1.50/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
- Product
- 4-BROMOOXINDOLE 99365-48-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10