ChemicalBook > CAS DataBase List > 4-BROMOOXINDOLE

4-BROMOOXINDOLE

Product Name
4-BROMOOXINDOLE
CAS No.
99365-48-7
Chemical Name
4-BROMOOXINDOLE
Synonyms
4-Bromoindolin-2-one;4-BROMOOXINDOLE;4-Bromo-2-oxindole;4-BROMO-2-OXYINDOLE;4-Bromooxindole ,98%;4-broMo-1H-indol-1-ol;4-bromo-2H-indol-2-one;4-BroMo-1,3-dihydro-indol-2-one;4-Bromo-1,3-dihydro-2H-indol-2-one;4-Bromo-2,3-dihydro-1H-indol-2-one
CBNumber
CB1753046
Molecular Formula
C8H6BrNO
Formula Weight
212.04
MOL File
99365-48-7.mol
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4-BROMOOXINDOLE Property

Melting point:
202-208
Boiling point:
358.2±42.0 °C(Predicted)
Density 
1.666±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
13.24±0.20(Predicted)
color 
White to Light yellow to Light orange
InChI
InChI=1S/C8H6BrNO/c9-6-2-1-3-7-5(6)4-8(11)10-7/h1-3H,4H2,(H,10,11)
InChIKey
XQQPPAZTHUEMPF-UHFFFAOYSA-N
SMILES
N1C2=C(C(Br)=CC=C2)CC1=O
CAS DataBase Reference
99365-48-7
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Safety

Hazard Codes 
Xn
Risk Statements 
22-37/38-41
Safety Statements 
26-39
HazardClass 
IRRITANT
HS Code 
2933790090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B5903
Product name
4-Bromoindolin-2-one
Packaging
200MG
Price
$55
Updated
2025/07/31
TCI Chemical
Product number
B5903
Product name
4-Bromoindolin-2-one
Packaging
1G
Price
$186
Updated
2025/07/31
Apolloscientific
Product number
OR1230
Product name
4-Bromo-2-oxindole
Packaging
500mg
Price
$27
Updated
2021/12/16
SynQuest Laboratories
Product number
4H48-9-W0
Product name
4-Bromo-2-oxindole
Packaging
500mg
Price
$29
Updated
2021/12/16
Apolloscientific
Product number
OR1230
Product name
4-Bromo-2-oxindole
Packaging
1g
Price
$38
Updated
2021/12/16
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4-BROMOOXINDOLE Chemical Properties,Usage,Production

Uses

4-Bromooxindole is a reactant that has been used in the preparation of benzylidene bromo isatin derivatives with antitumor activity.

Synthesis

37777-74-5

99365-48-7

To a stirred solution of 2-(2-bromo-6-nitrophenyl)acetic acid (0.66 g, 2.54 mmol) dissolved in a solvent mixture of 50% H2SO4 (6.0 mL) and EtOH (10.0 mL), zinc powder (0.66 g, 10.1 mmol) was added, and the reaction was carried out at 90 °C in an N2 atmosphere. After completion of the reaction, the reaction mixture was treated according to a similar method as in preparation 5 to give the intermediate 4-bromoindolone (0.50 g, 93% yield). The mass spectrum (electrospray ionization) showed an M+1 peak of 212 and an M+2 peak of 214.

References

[1] Patent: US2003/225127, 2003, A1. Location in patent: Page 16
[2] Chemical and Pharmaceutical Bulletin, 1985, vol. 33, # 4, p. 1414 - 1418

4-BROMOOXINDOLE Preparation Products And Raw materials

Raw materials

ZINC 2-Bromo-6-nitrotoluene Hydrogen peroxide Diethyl oxalate Sodium Methoxide Hydrochloric acid Sulfuric acid

Preparation Products

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View Lastest Price from 4-BROMOOXINDOLE manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
4-BROMOOXINDOLE 99365-48-7
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-07
Henan Fengda Chemical Co., Ltd
Product
4-BROMOOXINDOLE 99365-48-7
Price
US $36.00-1.50/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-BROMOOXINDOLE 99365-48-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

99365-48-7, 4-BROMOOXINDOLERelated Search:

4-BROMOISATIN 4-(4-Bromo-phenyl)-pyridine 4-BROMO-5-FLUORO-7-METHYL ISATIN 4-BROMO-7-METHYLISATIN 4-Bromo-5-methyl-2,3-indolinedione 4-BROMOOXINDOLE 5-BROMOOXINDOLE,5-Bromooxindole ,98% 7-bromoindolin-2-one BROMOOXINDOLE (6-),6-BROMOOXINDOLE 4-Bromoindole 4,6-DIBROMO ISATIN 4-BROMO-5-CHLOROINDOLINE-2,3-DIONE 4-bromo-3-[(2,2,2-trifluoroethyl)amino]-1,3-dihydro-2H-indol-2-one 4-BROMO-5-METHOXYINDOLINE-2,3-DIONE 4-bromo-3-(methylamino)-1,3-dihydro-2H-indol-2-one 2-[(4-bromo-2-oxo-2,3-dihydro-1H-indol-3-yl)amino]acetamide 3-amino-4-bromo-1,3-dihydro-2H-indol-2-one 4-bromo-3-(ethylamino)-1,3-dihydro-2H-indol-2-one

  • 4-BROMOOXINDOLE
  • 4-BROMO-2-OXYINDOLE
  • 4-Bromoindolin-2-one
  • 4-Bromo-2-oxindole
  • 4-Bromooxindole ,98%
  • 4-BroMo-1,3-dihydro-indol-2-one
  • 4-BroMo-2,3-dihydro-1H-indol-2-one, 97%+
  • 4-Bromo-2,3-dihydro-1H-indol-2-one
  • 4-Bromo-1,3-dihydro-2H-indol-2-one
  • 4-broMo-1H-indol-1-ol
  • 2H-Indol-2-one, 4-broMo-1,3-dihydro-
  • 4-BROMOOXINDOLE in stock Factory
  • 4-bromo-2H-indol-2-one
  • 99365-48-7
  • 99265-48-7
  • Indoline & Oxindole
  • blocks
  • Bromides
  • IndolesOxindoles