3-BROMO-4-IODOTOLUENE
- Product Name
- 3-BROMO-4-IODOTOLUENE
- CAS No.
- 71838-16-9
- Chemical Name
- 3-BROMO-4-IODOTOLUENE
- Synonyms
- 2-Bromo-1-iodo-4-methylbenzene;3-BROMO-4-IODOTOLUENE;1-BROMO-2-IODO-5-METHYLBENZENE;Benzene, 2-bromo-1-iodo-4-methyl-
- CBNumber
- CB1754391
- Molecular Formula
- C7H6BrI
- Formula Weight
- 296.93
- MOL File
- 71838-16-9.mol
3-BROMO-4-IODOTOLUENE Property
- Melting point:
- 265-267 °C
- Boiling point:
- 133 °C
- Density
- 2,08 g/cm3
- refractive index
- 1.65
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- clear liquid
- color
- Light yellow to Brown
- Specific Gravity
- 2.08
- InChI
- InChI=1S/C7H6BrI/c1-5-2-3-7(9)6(8)4-5/h2-4H,1H3
- InChIKey
- PLAKKSAFIZVHJP-UHFFFAOYSA-N
- SMILES
- C1(I)=CC=C(C)C=C1Br
- CAS DataBase Reference
- 71838-16-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 29039990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B5284
- Product name
- 3-Bromo-4-iodotoluene
- Packaging
- 5G
- Price
- $17
- Updated
- 2025/07/31
- Product number
- B5284
- Product name
- 3-Bromo-4-iodotoluene
- Packaging
- 25G
- Price
- $72
- Updated
- 2025/07/31
- Product number
- B685720
- Product name
- 3-Bromo-4-iodotoluene
- Packaging
- 10g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- B685720
- Product name
- 3-Bromo-4-iodotoluene
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- HCH0021273
- Product name
- 3-BROMO-4-IODOTOLUENE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $123.9
- Updated
- 2021/12/16
3-BROMO-4-IODOTOLUENE Chemical Properties,Usage,Production
Uses
3-Bromo-4-iodotoluene, is an intermediate for the synthesis of more complex compounds. It is used for the copper-catalyzed synthesis of 2-Arylbenzoxazoles.
Synthesis
583-68-6
71838-16-9
General procedure for the synthesis of 3-bromo-4-iodotoluene from 2-bromo-4-methylaniline: 2-bromo-4-methylaniline (5 g, 29 mmol) was dissolved in acetonitrile (80 mL), and an aqueous hydrochloric acid solution prepared from concentrated hydrochloric acid (15 mL) and water (50 mL) was added. The reaction mixture was cooled to 0 °C and a solution of sodium nitrite (2.4 g, 34.87 mmol) in water (50 mL) was added slowly. After addition, the reaction temperature was kept below 5°C for 30 min. Subsequently, a solution of potassium iodide (7.23 g, 43.59 mmol) in water (50 mL) was added. After addition, the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was poured into water (300 mL) and extracted with dichloromethane. The organic phases were combined and dried over anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure to give a brown oil, which was purified by distillation to give the light yellow target product 3-bromo-4-iodotoluene.
References
[1] Tetrahedron Letters, 2012, vol. 53, # 39, p. 5248 - 5252
[2] Angewandte Chemie - International Edition, 2007, vol. 46, # 25, p. 4744 - 4747
[3] Chemistry - A European Journal, 2016, vol. 22, # 6, p. 1941 - 1943
[4] Justus Liebigs Annalen der Chemie, 1873, vol. 168, p. 153
[5] Justus Liebigs Annalen der Chemie, 1878, vol. 192, p. 202
3-BROMO-4-IODOTOLUENE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-BROMO-4-IODOTOLUENE manufacturers
- Product
- 3-BROMO-4-IODOTOLUENE 71838-16-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10tons
- Release date
- 2020-02-18