5-Nitroindole

Product Name: 5-Nitroindole
CAS No.: 6146-52-7
Chemical Name: 5-Nitroindole
Synonyms: 5-NITRO-1H-INDOLE;NSC 520594;Nitroindole;5-nitro-indol;5-NITROINDOLE;5-INTRO INDOLE;5-Nitroindole>5-Nitroindole,99%;5-Nitroindole,98+%;1H-Indole, 5-nitro-
CBNumber: CB1758162
Molecular Formula: C8H6N2O2
Formula Weight: 162.15
MOL File: 6146-52-7.mol

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5-Nitroindole Property

Melting point:: 140-142 °C (lit.)
Boiling point:: 288.82°C (rough estimate)
Density: 1.3264 (rough estimate)
refractive index: 1.5770 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Dichloromethane, Ethyl Acetate, Methanol
form: Crystalline Powder or Needles
pka: 15.25±0.30(Predicted)
color: Yellow
BRN: 383777
InChI: InChI=1S/C8H6N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-5,9H
InChIKey: OZFPSOBLQZPIAV-UHFFFAOYSA-N
SMILES: N1C2=C(C=C([N+]([O-])=O)C=C2)C=C1
CAS DataBase Reference: 6146-52-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-41
Safety Statements: 26-39-45-36/37
WGK Germany: 3
RTECS: NM1168200
F: 8
Hazard Note: Irritant
HazardClass: IRRITANT, IRRITANT-HARMFUL
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N17602
Product name: 5-Nitroindole
Purity: 98%
Packaging: 5g
Price: $53.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: N17602
Product name: 5-Nitroindole
Purity: 98%
Packaging: 25g
Price: $107
Updated: 2025/07/31

TCI Chemical

Product number: N0400
Product name: 5-Nitroindole
Purity: >98.0%(GC)
Packaging: 5g
Price: $66
Updated: 2025/07/31

TCI Chemical

Product number: N0400
Product name: 5-Nitroindole
Purity: >98.0%(GC)
Packaging: 25g
Price: $263
Updated: 2025/07/31

TRC

Product number: N496280
Product name: 5-Nitroindole
Packaging: 25g
Price: $150
Updated: 2021/12/16

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5-Nitroindole Chemical Properties,Usage,Production

Chemical Properties

Yellow-Green Cyrstalline Solid, soluble in ethanol, diethyl ether, propylene glycol, petroleum ether and most non-volatile oils, insoluble in glycerol and mineral oils.

Application

Reactant for preparation of:

Pharmaceutically active 2-oxo-1-pyrrolidine analogues
Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
Protein Kinase Inhibitors and antiproliferative agents
Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)
Antifungal agents
Cannabinoid receptor type 1 (CB1) antagonists
Potential anticancer agents
Potential antivascular agents
Selective Anti-leukemic agents
Anti human immunodeficiency virus subtype 1 (HIV-1) agents

Uses

5-Nitroindole (cas# 6146-52-7) is a reagent involved in the synthesis of a variety of biochemical compounds, including: 2-oxo-1-pyrrolidine analogs, mGlu4 allosteric modulators, protein kinase inhibitors, antiproliferative agents, anti-HIV 1 agents, antifungal agents, anti-leukemic agents, antivascular agents, anticancer agents, and cannabinoid receptor type 1 (CB1) antagonists.

Purification Methods

Decolourise (charcoal) 5-nitroindole and recrystallise it twice from aqueous EtOH or recrystallise it from octane. It has UV: 265 and 324nm (EtOH). [Beilstein 20 III/IV 3194, 20/7 V 41.]

5-Nitroindole Preparation Products And Raw materials

Raw materials

Sodium acetate Quinoline Ethanol Acetic anhydride Ethyl pyruvate Sodium bisulfite Polyphosphoric acid Tetrahydrofuran Cupric oxide 4-Nitrophenylhydrazine Ethyl acetate Hydrochloric acid Sodium bicarbonate Nitric acid Acetic acid Sodium hydroxide Indole

Preparation Products

1-METHYL-5-NITRO-1H-INDOLE 5-IODOINDOLE Zafirlukast

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5-Nitroindole Suppliers

Americas 1 Austria 1 Belgium 2 Canada 4 China 340 Czech Republic 1 Europe 3 Germany 9 India 55 Japan 4 Slovakia 1 South Korea 1 Switzerland 4 Ukraine 1 United Kingdom 24 United States 68 Global 519

Changzhou Joyous Chemical Co., Ltd.

Tel: 0519-85607258 13912342323;
Fax: 0519-85607278
Email: sales@joyouschem.com
Country: China
ProdList: 294
Advantage: 60

BEIJING GOLDEN OLIVE COMPANY

Tel: 010-82904532 15311296095
Email: mary@goldolive.com
Country: China
ProdList: 86
Advantage: 58

Shanghai Alan Pharmaceutical Co., LTD

Tel: 021-58099609-8008 13816260319
Email: 251218799@qq.com
Country: China
ProdList: 139
Advantage: 58

Jinan Dexinjia Bio&Tech Co., Ltd

Tel: 0531-82371986 15269101859
Fax: 0531-82375893
Email: 3276840968@qq.com
Country: China
ProdList: 1604
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

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View Lastest Price from 5-Nitroindole manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 5-NITRO-1H-INDOLE 6146-52-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-19

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Nitroindole 6146-52-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-09

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-Nitroindole 6146-52-7
Price: US $1.00/PCS
Min. Order: 1PCS
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-10

6146-52-7, 5-NitroindoleRelated Search:

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5-NITROINDOLE

5-NITRO-1H-INDOLE

5-nitro-indol

Nitroindole

5-Nitroindole,99%

5-Nitroindole,98+%

NSC 520594

5-Nitroindolyl radical

1H-Indole, 5-nitro-

5-Nitroindole in stock Factory

5-Nitroindole&gt

5-INTRO INDOLE

INDOLE DERIVATIVE6146-52-7

5-nitro-1H-indole - [N31173]

6146-52-7

C8H6NO2

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