ChemicalBook > CAS DataBase List > 5-Nitroindole
5-Nitroindole
- Product Name
- 5-Nitroindole
- CAS No.
- 6146-52-7
- Chemical Name
- 5-Nitroindole
- Synonyms
- 5-NITRO-1H-INDOLE;NSC 520594;Nitroindole;5-nitro-indol;5-NITROINDOLE;5-INTRO INDOLE;5-Nitroindole>5-Nitroindole,99%;5-Nitroindole,98+%;1H-Indole, 5-nitro-
- CBNumber
- CB1758162
- Molecular Formula
- C8H6N2O2
- Formula Weight
- 162.15
- MOL File
- 6146-52-7.mol
More
Less
5-Nitroindole Property
- Melting point:
- 140-142 °C (lit.)
- Boiling point:
- 288.82°C (rough estimate)
- Density
- 1.3264 (rough estimate)
- refractive index
- 1.5770 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Dichloromethane, Ethyl Acetate, Methanol
- form
- Crystalline Powder or Needles
- pka
- 15.25±0.30(Predicted)
- color
- Yellow
- BRN
- 383777
- InChI
- InChI=1S/C8H6N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-5,9H
- InChIKey
- OZFPSOBLQZPIAV-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C([N+]([O-])=O)C=C2)C=C1
- CAS DataBase Reference
- 6146-52-7(CAS DataBase Reference)
More
Less
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-41
- Safety Statements
- 26-39-45-36/37
- WGK Germany
- 3
- RTECS
- NM1168200
- F
- 8
- Hazard Note
- Irritant
- HazardClass
- IRRITANT, IRRITANT-HARMFUL
- HS Code
- 29339900
More
Less
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- N17602
- Product name
- 5-Nitroindole
- Purity
- 98%
- Packaging
- 5g
- Price
- $53.6
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- N17602
- Product name
- 5-Nitroindole
- Purity
- 98%
- Packaging
- 25g
- Price
- $107
- Updated
- 2025/07/31
TCI Chemical
- Product number
- N0400
- Product name
- 5-Nitroindole
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $66
- Updated
- 2025/07/31
TCI Chemical
- Product number
- N0400
- Product name
- 5-Nitroindole
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $263
- Updated
- 2025/07/31
TRC
- Product number
- N496280
- Product name
- 5-Nitroindole
- Packaging
- 25g
- Price
- $150
- Updated
- 2021/12/16
More
Less
5-Nitroindole Chemical Properties,Usage,Production
Chemical Properties
Yellow-Green Cyrstalline Solid, soluble in ethanol, diethyl ether, propylene glycol, petroleum ether and most non-volatile oils, insoluble in glycerol and mineral oils.
Application
Reactant for preparation of:
- Pharmaceutically active 2-oxo-1-pyrrolidine analogues
- Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Protein Kinase Inhibitors and antiproliferative agents
- Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)
- Antifungal agents
- Cannabinoid receptor type 1 (CB1) antagonists
- Potential anticancer agents
- Potential antivascular agents
- Selective Anti-leukemic agents
- Anti human immunodeficiency virus subtype 1 (HIV-1) agents
Uses
5-Nitroindole (cas# 6146-52-7) is a reagent involved in the synthesis of a variety of biochemical compounds, including: 2-oxo-1-pyrrolidine analogs, mGlu4 allosteric modulators, protein kinase inhibitors, antiproliferative agents, anti-HIV 1 agents, antifungal agents, anti-leukemic agents, antivascular agents, anticancer agents, and cannabinoid receptor type 1 (CB1) antagonists.
Purification Methods
Decolourise (charcoal) 5-nitroindole and recrystallise it twice from aqueous EtOH or recrystallise it from octane. It has UV: 265 and 324nm (EtOH). [Beilstein 20 III/IV 3194, 20/7 V 41.]
5-Nitroindole Preparation Products And Raw materials
Raw materials
Sodium acetate
Quinoline
Ethanol
Acetic anhydride
Ethyl pyruvate
Sodium bisulfite
Polyphosphoric acid
Tetrahydrofuran
Cupric oxide
4-Nitrophenylhydrazine
Ethyl acetate
Hydrochloric acid
Sodium bicarbonate
Nitric acid
Acetic acid
Sodium hydroxide
Indole
Preparation Products
More
Less
5-Nitroindole Suppliers
- Tel
- --
- Fax
- --
- porta@porta.cz
- Country
- Czech Republic
- ProdList
- 139
- Advantage
- 58
More
Less
View Lastest Price from 5-Nitroindole manufacturers
Shaanxi Dideu New Materials Co. Ltd
- Product
- 5-NITRO-1H-INDOLE 6146-52-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-19
Henan Aochuang Chemical Co.,Ltd.
- Product
- 5-Nitroindole 6146-52-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-09
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 5-Nitroindole 6146-52-7
- Price
- US $1.00/PCS
- Min. Order
- 1PCS
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2025-03-10
6146-52-7, 5-NitroindoleRelated Search:
2-Methylindole
Indole-3-acetic acid
Indometacin
Indole
Indole-3-butyric acid
2-METHYL-5-NITROINDOLE
5-NITROINDOLE-2-CARBOXYLIC ACID
2,3-DIMETHYL-5-NITROINDOLE
2-METHYL-5-NITROINDOLE-3-CARBOXALDEHYDE,3-FORMYL-2-METHYL-5-NITROINDOLE
NITROGEN DIOXIDE
5-NITROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER
1,3,6,8-TETRANITROCARBAZOLE
9-Ethyl-3-nitrocarbazole
5-NITRO-3-PHENYL-1H-INDOLE-2-CARBOXYLIC ACID
6-Nitrooxidole
3-(DIMETHYLAMINOMETHYL)-6-NITROINDOLE
2,3-DIMETHYL-7-NITROINDOLE
1-ACETYL-5-NITROINDOLINE