ChemicalBook > CAS DataBase List > Thiodiglycolic Anhydride

Thiodiglycolic Anhydride

Product Name: Thiodiglycolic Anhydride
CAS No.: 3261-87-8
Chemical Name: Thiodiglycolic Anhydride
Synonyms: 1,4-OXATHIANE-2,6-DIONE;1,4-Oxathiane-2,6-dione (Thiodiglycolic anhydride);NSC 147625;THIODIGLYCOLIC ANHYDRIDE;Thiodilycolic Anhydride;2,2'-Thiobisacetic anhydride;2,2'-THIODIACETIC ACID ANHYDRIDE;1-Oxa-4-thia-cyclohexan-2,6-dione;1,4-OXATHIANE-2,6-DIONE
THIODIGLYCOLIC ANHYDRIDE;1,4-Oxathiane-2,6-dione~2,2-Thiodiacetic acid anhydride
CBNumber: CB1765467
Molecular Formula: C4H4O3S
Formula Weight: 132.14
MOL File: 3261-87-8.mol

Less

Thiodiglycolic Anhydride Property

Melting point:: 94 °C
Boiling point:: 158-159 °C(Press: 12 Torr)
Density: 1.468±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO, Methanol (Sparingly)
form: Solid
color: White to Off-White
Sensitive: Moisture Sensitive
BRN: 112528
InChI: InChI=1S/C4H4O3S/c5-3-1-8-2-4(6)7-3/h1-2H2
InChIKey: RIIUAPMWDSRBSH-UHFFFAOYSA-N
SMILES: O1C(=O)CSCC1=O
CAS DataBase Reference: 3261-87-8(CAS DataBase Reference)

Less

Safety

Hazard Codes: C,Xn
Risk Statements: 20/21/22-34-22
Safety Statements: 26-36/37/39
RIDADR: 3261
Hazard Note: Corrosive
PackingGroup: III
HS Code: 2934999090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

Usbiological

Product number: 467527
Product name: Thiodiglycolic Anhydride
Packaging: 5g
Price: $355
Updated: 2021/12/16

TRC

Product number: T344525
Product name: ThiodiglycolicAnhydride
Packaging: 5g
Price: $95
Updated: 2021/12/16

AK Scientific

Product number: 4562BA
Product name: 1,4-Oxathiane-2,6-dione
Packaging: 100g
Price: $112
Updated: 2021/12/16

Apolloscientific

Product number: OR28488
Product name: 1,4-Oxathiane-2,6-dione
Packaging: 5g
Price: $44
Updated: 2021/12/16

SynQuest Laboratories

Product number: 6H66-1-00
Product name: 1,4-Oxathiane-2,6-dione
Packaging: 5G
Price: $48
Updated: 2021/12/16

Less

Thiodiglycolic Anhydride Chemical Properties,Usage,Production

Chemical Properties

White needle-shaped crystal

Uses

Thiodiglycolic Anhydride is used as a reagent in the synthesis of positively charged compounds as SERT inhibitors useful in the treatment of central nervous system (CNS) disorders.

Synthesis

123-93-3

3261-87-8

3.0 g of 2,2'-thiodiacetic acid was accurately weighed in a 50 mL round bottom flask. To the flask was added 15 mL of acetic anhydride as reaction solvent. The reaction mixture was heated to 65 °C and kept at reflux for 4 hours. Upon completion of the reaction, the excess acetic anhydride and the by-product acetic acid were removed by distillation under reduced pressure. Subsequently, an appropriate amount of ether was added to the residue and the evaporation operation was repeated 2-3 times to purify the product. The final product was obtained as 2,2'-thiodiacetic anhydride in the form of a white solid powder and the product was dried at 40 °C overnight in 98.7% yield.

References

[1] Patent: CN108245683, 2018, A. Location in patent: Paragraph 0051; 0053
[2] Organic Letters, 2015, vol. 17, # 15, p. 3930 - 3933
[3] Tetrahedron Letters, 2017, vol. 58, # 32, p. 3160 - 3163
[4] Tetrahedron Letters, 2002, vol. 43, # 8, p. 1519 - 1522
[5] Tetrahedron Letters, 2017, vol. 58, # 37, p. 3672 - 3677

Thiodiglycolic Anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Thiodiglycolic Anhydride Suppliers

Belgium 1 China 152 Germany 2 India 4 United Kingdom 11 United States 10 Global 180

Sanmenxia Aoke Chemical Industry Co., Ltd.

Tel: 0398-3711988 13525866741
Email: aokechem@aokeby.com
Country: China
ProdList: 218
Advantage: 58

Wuhan BJM Pharm Inc

Tel: 18607102166 18607102166
Email: sales04@benjaminpharmchem.com
Country: China
ProdList: 228
Advantage: 58

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Nanjing Vital Chemical Co., Ltd.

Tel: Please Send Email 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 4378
Advantage: 65

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4566
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
ProdList: 5872
Advantage: 58

Shanghai Balmxy Pharmaceutical Co., Ltd

Tel: 021-24206007 13764915196
Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
ProdList: 6874
Advantage: 55

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Quzhou Rundong Chemical (Technology) Co.

Tel: 0570-8789886 18892685668
Fax: 0570-8789985
Email: info@rundongchemical.com
Country: China
ProdList: 4053
Advantage: 60

Struchem Co., Ltd.

Tel: 0512-63009836 18994340901
Fax: 0512-63006936
Email: helen@struchem.com
Country: China
ProdList: 3981
Advantage: 60

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

Nanjing Vital Chemical Co., Ltd.

Tel: 025-87193546 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 9021
Advantage: 60

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 3495
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Yihe Biological Technology Co., Ltd.

Tel: 021-68882955 17721395025
Fax: 021-68882955
Email: 2423903095@qq.com
Country: China
ProdList: 4992
Advantage: 58

Shijiazhuang Yesheng Chemical Technology Co., Ltd

Tel: 18031147013 18031147013;
Fax: 0311-68030586
Email: yeshengchemical@163.com
Country: China
ProdList: 2606
Advantage: 58

Hefei Hirisun Pharmatech Co., Ltd.

Tel: +86-0551-62678551 +86-15056975894
Fax: 05512678551
Email: sales@hirisunpharm.com
Country: China
ProdList: 176
Advantage: 55

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Siling(shanghai) chemical Technology Co., Ltd.

Tel: 021-64149925
Fax: 021-64149925
Email: 13761470417@163.com
Country: China
ProdList: 220
Advantage: 55

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10330
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-63315541 13323832564
Fax: QQ:3001332135
Email: 3001332135@qq.com
Country: China
ProdList: 9972
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Finetech Industry Limited

Tel: +86-27-8746-5837 +8619945049750
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9629
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Hefei Hirisun Pharmatech Co., Ltd

Tel: +8615056975894
Fax: 86-0551-62678551
Email: shawn@hirisunpharm.com
Country: CHINA
ProdList: 9911
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Less

View Lastest Price from Thiodiglycolic Anhydride manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: THIODIGLYCOLIC ANHYDRIDE 3261-87-8
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-11-20

Career Henan Chemical Co

Product: THIODIGLYCOLIC ANHYDRIDE 3261-87-8
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-10

3261-87-8, Thiodiglycolic AnhydrideRelated Search:

o-Anisaldehyde 4-Chlorobenzoic acid 4-Methoxyphenylacetic acid 3-(4-Hydroxyphenyl)propionic acid Octadecylphosphonic acid 4-Bromochlorobenzene THIODIGLYCOLIC ANHYDRIDE, (2,2'-THIODIACETIC ACID ANHYDRIDE) 1,4-Oxathiane 3-METHYL-1,4-OXATHIANE-2,6-DIONE THIODIGLYCOLIC ANHYDRIDE

2,2'-THIODIACETIC ACID ANHYDRIDE

1,4-OXATHIANE-2,6-DIONE

THIODIGLYCOLIC ANHYDRIDE

1-Oxa-4-thia-cyclohexan-2,6-dione

1,4-Oxathiane-2,6-dione~2,2-Thiodiacetic acid anhydride

1,4-Oxathiane-2,6-dione (Thiodiglycolic anhydride)

1,4-OXATHIANE-2,6-DIONE<BR> THIODIGLYCOLIC ANHYDRIDE

2,2'-Thiobisacetic anhydride

Thiodilycolic Anhydride

NSC 147625

3261-87-8

3621-87-8

C4H4O3S