BOC-DL-MET-OH

Product Name: BOC-DL-MET-OH
CAS No.: 93000-03-4
Chemical Name: BOC-DL-MET-OH
Synonyms: Boc-DL-Met;BOC-DL-MET-OH;BOC-DL-METHIONINE;N-Boc-DL-methionine;Boc-DL-methionine99%;BOC-DL-MET-OH USP/EP/BP;N-Boc-DL-Methionine, ≥98%;(tert-Butoxycarbonyl)methionine;N-T-BUTOXYCARBONYL-DL-METHIONINE;N-tert-Butoxycarbonyl-DL-methionine
CBNumber: CB1766237
Molecular Formula: C10H19NO4S
Formula Weight: 249.33
MOL File: 93000-03-4.mol

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BOC-DL-MET-OH Property

Boiling point:: 415.5±40.0 °C(Predicted)
Density: 1.160±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
form: Solid
pka: 3.83±0.10(Predicted)
color: White to off-white
CAS DataBase Reference: 93000-03-4

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Safety

HS Code: 29309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B658965
Product name: BOC-DL-Met-OH
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Usbiological

Product number: 236273
Product name: Boc-DL-methionine 99+%
Packaging: 5g
Price: $186
Updated: 2021/12/16

Usbiological

Product number: 264886
Product name: Boc-DL-methionine
Packaging: 10g
Price: $343
Updated: 2021/12/16

Chem-Impex

Product number: 04004
Product name: Boc-DL-methionine,≥99%(HPLC)
Purity: ≥99%(HPLC)
Packaging: 5G
Price: $36.22
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB47930
Product name: Boc-DL-methionine
Packaging: 5G
Price: $60
Updated: 2021/12/16

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BOC-DL-MET-OH Chemical Properties,Usage,Production

Uses

(tert-Butoxycarbonyl)methionine is a Methionine.html" class="link-product" target="_blank">Methionine (HY-13694) derivative[1].

Synthesis

24424-99-5

59-51-8

93000-03-4

General procedure for the synthesis of 2-((tert-butoxycarbonyl)amino)-4-(methylthio)butanoic acid from di-tert-butyl dicarbonate and DL-methionine: DL-methionine (20 g, 0.134 mol) was dissolved in 250 mL of a 10% aqueous sodium carbonate solution and cooled to 0 °C. A solution of di-tert-butyl dicarbonate (32.17 g, 0.147 mol) dissolved in 100 mL of dioxane was slowly added dropwise over a period of 1 hour. After the dropwise addition was completed, the cooling bath was removed and the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, about half of the solvent was removed by evaporation under reduced pressure. The reaction mixture was cooled with an ice bath and the pH was adjusted to 2-3 with 10% aqueous citric acid.The aqueous phase was extracted with ethyl acetate (3 x 200 mL) and the organic layers were combined and washed sequentially with 200 mL of water and 200 mL of saturated saline (2 x 200 mL). The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue was ground with mixed solvent ethyl acetate-petroleum ether at -20 °C to give the pure product 2-((tert-butoxycarbonyl)amino)-4-(methylthio)butanoic acid (28 g, 84% yield). The product was a white solid with a melting point of 88-90 °C (literature value 87-91 °C). Thin layer chromatography (TLC) Rf = 0.67 (unfolding agent S4).1H NMR (600 MHz, CDCl3) δ: 5.27 (br s, 1H, NH), 4.45 (m, 1H), 2.58 (t, J = 7.5 Hz, 2H), 2.18 (m, 1H), 2.11 (s, 3H, SCH3), 1.98 (m, 1H). 1.45 (s, 9H, t-Bu).13C NMR (150.9 MHz, CDCl3) δ: 176.91 (COOH), 155.60 (NCOO), 80.32, 52.73, 31.86, 29.93, 28.24 (3C), 15.32.IR (KBr) νmax (cm-1): 3380 ( NH), 3500-2800 (br, COOH), 1715 (C=O, acid), 1673 (C=O, carbamate), 1543 (amide II), 2977 (s), 1368 (m, CH3). High resolution mass spectrometry (HRMS-ESI) calculated value C10H19O4NNaS [M+Na]+: 272.09270, measured value: 272.09281.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

BOC-DL-MET-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-DL-MET-OH Suppliers

China 81 India 2 Japan 1 United Kingdom 4 United States 9 Global 97

J & K SCIENTIFIC LTD.

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SINO High Goal Chemical Technology Co., Ltd.

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View Lastest Price from BOC-DL-MET-OH manufacturers

Career Henan Chemical Co

Product: BOC-DL-MET-OH 93000-03-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-16

93000-03-4, BOC-DL-MET-OHRelated Search:

BOC-MET(O)-OH BOC-L-Methionine BOC-D-Methionine BOC-MET-OSU BOC-MET-OH DCHA BOC-DL-MET-OH BOC-MET(O2)-OH BOC-D-METHIONINE DICYCLOHEXYLAMINE SALT BOC-HOCYS(BZL)-OH BOC-D-MET-OSU (S)-2-(BOC-AMINO)-4-(4-METHYL-BENZYLSULFANYL)BUTYRIC ACID BOC-HOMOCYS(TRT)-OH BPOC-MET-OH DCHA BOC-L-MET-O-CH2-PHI-CH2-COOH BOC-MET-ONP BOC-L-MET(O)-O-CH2-PHI-CH2-COOH DCHA LABOTEST-BB LT00160053 BOC-MET-OH-13C1 (METHYL-13C)

N-[(1,1-Dimethylethoxy)Carbonyl]-Methionine

N-tert-Butoxycarbonyl-DL-methionine

BOC-DL-METHIONINE

BOC-DL-MET-OH

N-T-BUTOXYCARBONYL-DL-METHIONINE

Boc-DL-methionine99%

N-Boc-DL-methionine

Boc-DL-Met

(tert-Butoxycarbonyl)methionine

N-Boc-DL-Methionine, ≥98%

2-{[(tert-butoxy)carbonyl]amino}-4-(methylsulfanyl)butanoic acid

2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoicaci

BOC-DL-MET-OH USP/EP/BP

Methionine, N-[(1,1-dimethylethoxy)carbonyl]-

(tert-Butoxycarbonyl)methionine - [B92213]

93000-03-4