ChemicalBook > CAS DataBase List > 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE

1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE

Product Name: 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE
CAS No.: 73465-43-7
Chemical Name: 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE
Synonyms: DMM;DMJ;DMJ, HYDROCHLORIDE;DEOXYMANNOJIRIMYCIN HCL;1-DEOXYMANNOJIRIMYCIN HCL;DEOXYMANNONOJIRIMYCIN HCL;1-DeoxymannojirimycineHCl;DEOXYMANNOJIRIMYCIN, HYDROCHLORIDE;1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE;1-Deoxymannojirimycinehydrochloride
CBNumber: CB1768822
Molecular Formula: C6H14ClNO4
Formula Weight: 199.63
MOL File: 73465-43-7.mol

Less

1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Property

Melting point:: 183-185°C
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: H2O: soluble10mg/mL
form: Powder
color: white to off-white
Water Solubility: Soluble in water (50 mM)
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
CAS DataBase Reference: 73465-43-7

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 22-24/25-36-37/39-26
WGK Germany: 3
HS Code: 2941900000

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D9160
Product name: 1-Deoxymannojirimycin hydrochloride
Packaging: 1mg
Price: $148
Updated: 2025/07/31

Sigma-Aldrich

Product number: D9160
Product name: 1-Deoxymannojirimycin hydrochloride
Packaging: 5mg
Price: $396
Updated: 2025/07/31

Cayman Chemical

Product number: 17178
Product name: 1-Deoxymannojirimycin (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $28
Updated: 2024/03/01

Cayman Chemical

Product number: 17178
Product name: 1-Deoxymannojirimycin (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $84
Updated: 2024/03/01

Sigma-Aldrich

Product number: D9160
Product name: 1-Deoxymannojirimycin hydrochloride
Packaging: 10mg
Price: $704.69
Updated: 2025/07/31

Less

1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Chemical Properties,Usage,Production

Description

1-Deoxymannojirimycin is a specific inhibitor of class I α-1,2-mannosidase (IC₅₀ = 0.02 μM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi and for targeting misfolded proteins for translocation out of the endoplasmic reticulum and degradation by the proteasome. By inhibiting α-1,2-mannosidase activity, this compound generates N-linked oligosaccharides with high mannose content, preventing misfolded protein degradation. This compound has been used for studies on glycoprotein processing and as a model for the development of anticancer and antiviral therapies.

Chemical Properties

White Crystalline Solid

Uses

Selective inhibitor of a-mannosidase

Uses

Deoxymannojirimycin has been shown to be a potent inhibitor of the mammalian Golgi alpha- mannosidase 1 activity, blocking the conversion of high-mannose oligosaccharides to complex-type oligosaccharides. However, it does not inhibit the biosynthesis of lipid- linked oligosaccharides.

storage

+4°C

References

[1] J BISCHOFF R K L Liscum. The use of 1-deoxymannojirimycin to evaluate the role of various alpha-mannosidases in oligosaccharide processing in intact cells.[J]. The Journal of Biological Chemistry, 1986, 261 10: 4766-4774.
[2] JOYCE BISCHOFF Rosalind K. The effect of 1-deoxymannojirimycin on rat liver α-mannosidases[J]. Biochemical and biophysical research communications, 1984, 125 1: Pages 324-331. DOI:10.1016/s0006-291x(84)80371-x
[3] ULRIKE FUHRMANN. Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides[J]. Nature, 1984, 307 5953: 755-758. DOI:10.1038/307755a0
[4] KUNIO MIYAKE Kaoru N. Inhibition of α-mannosidase attenuates endoplasmic reticulum stress-induced neuronal cell death[J]. Neurotoxicology, 2009, 30 1: Pages 144-150. DOI:10.1016/j.neuro.2008.10.010
[5] APRIL TAI. Production of lentiviral vectors with enhanced efficiency to target dendritic cells by attenuating mannosidase activity of mammalian cells.[J]. Journal of Biological Engineering, 2011, 5 1: 1. DOI:10.1186/1754-1611-5-1
[6] CHI-LIN LEE. Construction of stable producer cells to make high-titer lentiviral vectors for dendritic cell-based vaccination[J]. Biotechnology and Bioengineering, 2011, 109 6: 1551-1560. DOI:10.1002/bit.24413

1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Suppliers

Canada 1 China 85 Germany 2 India 1 Italy 1 New Zealand 1 Russia 1 Switzerland 3 The Netherlands 1 United Kingdom 8 United States 18 Global 122

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4720
Advantage: 55

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Wuhan Fortuna Chemical Co., Ltd

Tel: +86-027-59207850 +86-13986145403;
Fax: 86-27-59524646
Email: info@fortunachem.com
Country: China
ProdList: 5987
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Hengyang Jiaxuan Biotechnology Co. LTD

Tel: 18684598761
Fax: QQ：675042965
Email: 675042965@qq.com
Country: China
ProdList: 308
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-025-85560043 17301488900
Fax: 025-85563444
Email: info@synzest.com
Country: China
ProdList: 9286
Advantage: 58

Shandong Nayazuo Chemical Technology Co. LTD

Tel: 400-873-6778 18660992876
Fax: 0539-6267369
Email: 3584419101@qq.com
Country: China
ProdList: 4970
Advantage: 58

Hangzhou Jinghao Biotechnology Co., LTD

Tel: 17513242016
Fax: QQ:1576861551
Email: 1576861551@qq.com
Country: China
ProdList: 2819
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 13675144456
Fax: 025-85563444
Email: sean.lv@synzest.com
Country: China
ProdList: 10784
Advantage: 58

Zhengzhou convergence chemical co., LTD

Tel: 0371-0371-55153829 18003835034
Email: 2853979819@qq.com
Country: China
ProdList: 9998
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Beijing Qinling Pharmaceutical Co., Ltd.

Tel: 010-61241352 18901327973
Email: 834537306@qq.com
Country: China
ProdList: 5860
Advantage: 58

Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 29784
Advantage: 58

LGC Science (Shanghai) Ltd.

Tel: 17717235263
Email: cindy.yang@lgcgroup.com
Country: China
ProdList: 18003
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Shanghai Saikerui Biotechnology Co. , Ltd.

Tel: 021-58000709 15900491054
Email: info@scrbio.com
Country: China
ProdList: 9881
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Beiwanta Biotechnology Co., Ltd.

Tel: 021-67187366 19901745723
Email: info@bwtlab.com
Country: China
ProdList: 9650
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29995
Advantage: 58

Auonsi (Shanghai) Biology Technology Co., Ltd.

Tel: 400-1107768 15058188853
Fax: 0571-88150696
Email: 478133536@qq.com
Country: China
ProdList: 8552
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co.,Ltd.

Tel: 0751-2815983 13927872582
Fax: 0751-2886750
Email: 2787852318@qq.com
Country: China
ProdList: 8050
Advantage: 58

Hubei Danding Pharmaceutical Technology Co., Ltd

Tel: 17701422019
Email: 1559451077@qq.com
Country: China
ProdList: 8167
Advantage: 58

Shanghai Weiyite Biotechnology Co., Ltd

Tel: 15317051735
Email: zhaojing@wytsci.com
Country: China
ProdList: 9980
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Enzo Biochem Inc

Tel: Enzo Biochem Inc. 13797054060
Email: Enzoname@qq.com
Country: China
ProdList: 6174
Advantage: 58

Tiancheng Chemical (Jiangsu) Co., Ltd

Tel: 0512-66387919 18662433356
Email: 18662433356@163.com
Country: China
ProdList: 10970
Advantage: 58

Jiangsu Xinsu New Materials Co., Ltd

Tel: 0512-66387919 15251950002
Email: 15251950002@163.com
Country: China
ProdList: 11046
Advantage: 58

Nanxing Chemical (Jiangsu) Co., Ltd

Tel: 0512-66387035 18662433356
Email: 18662433356@163.com
Country: China
ProdList: 10929
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Less

View Lastest Price from 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1-DeoxyMannojiriMycin hydrochloride 73465-43-7
Price: US $0.00/G
Min. Order: 10G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-15

73465-43-7, 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDERelated Search:

SKF 96365 HYDROCHLORIDE A 967079 GF109203X SWAINSONINE Bleomycin A5 Doxycycline Mannan Oligosaccharides terramycin hy drochloride,oxytetracycline hydrochl Clindamycin hydrochloride 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE (R)-3-ISOPROPYLAMINO-1,2-PROPANEDIOL 3-Hydroxypiperidine hydrochloride N-ButyldeoxymannojirimycinHCl (R)-3-Hydroxypiperidine hydrocloride 2-CHLORO-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL(1-3)-1-DEOXY-MANNOJIRIMYCIN DEOXYMANNOJIRIMYCIN

DMJ

DMJ, HYDROCHLORIDE

DMM

DEOXYMANNOJIRIMYCIN HCL

DEOXYMANNOJIRIMYCIN, HYDROCHLORIDE

DEOXYMANNONOJIRIMYCIN HCL

1,5-DIDEOXY-1,5-IMINO-D-MANNITOL, HCL

1,5-DIDEOXY-1,5-IMINO-D-MANNITOL HYDROCHLORIDE

1-DEOXYMANNOJIRIMYCIN HCL

(+)-1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE

1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE

(2R,3R,4R,5R)-2-(HYDROXYMETHYL)-3,4,5-PIPERIDINETRIOL HYDROCHLORIDE

1-DeoxymannojirimycineHCl

1-Deoxymannojirimycinehydrochloride

3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5R)-

1-Deoxymannojirimycin hydrochloride min. 98%

DMJ HCl, (2R,3R,4R,5R)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride

Manno-1-deoxynojiriMycin Hydrochloride

1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE USP/EP/BP

73465-43-7

C6H13NO4xHCl

Antibiotics A to Z

Antibiotics A-F

Antibiotics

BioChemical

Miscellaneous Natural Products

All Inhibitors

Glycosidase Inhibitors

Inhibitors