ChemicalBook > CAS DataBase List > 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE

2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE

Product Name
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
CAS No.
568544-03-6
Chemical Name
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
Synonyms
GSTO1-IN-1;GSTO1 inhibitor 1;2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE;2-Chloro-N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)acetamide;2-Chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]acetamide;Acetamide, 2-chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]-;GSTs,GSTO1IN1,Glutathione transferases,inhibit,Inhibitor,Gutathione S-transferase,GSTO1 IN 1,GSTO-1-IN-1
CBNumber
CB1774579
Molecular Formula
C10H12Cl2N2O3S
Formula Weight
311.18
MOL File
Mol file
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2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Property

storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0042397
Product name
GSTO1-IN-1
Purity
99.12%
Packaging
10mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0042397
Product name
GSTO1-IN-1
Purity
99.12%
Packaging
50mg
Price
$220
Updated
2021/12/16
ChemScene
Product number
CS-0042397
Product name
GSTO1-IN-1
Purity
99.12%
Packaging
100mg
Price
$380
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0058363
Product name
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
Purity
95.00%
Packaging
1G
Price
$692.46
Updated
2021/12/16
AK Scientific
Product number
0184CM
Product name
2-Chloro-N-[4-chloro-3-(dimethylsulfamoyl)phenyl]acetamide
Packaging
2.5g
Price
$784
Updated
2021/12/16
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2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Chemical Properties,Usage,Production

Biological Activity

GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with IC50 of 31 nM.

in vitro

GSTO1-IN-1 (C1-27) potently inhibits GSTO1 enzyme activity with an IC 50 value of 31 nM. GSTO1-IN-1 also potently competes with 5-chloromethylfluorescein diacetate (CMFDA) for binding to recombinant protein, as well as endogenous GSTO1 in the milieu of a soluble proteome. HCT116 cells treated with GSTO1-IN-1 also show a decrease in cell viability in a dose-dependent manner. GSTO1-IN-1 inhibits the clonogenic survival of HCT116 cells at sub-micromolar concentrations.

target

IC50: 31 nM (GSTO1)

2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Suppliers

China 17 Ukraine 2 United States 6 Global 25
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
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Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9355
Advantage
58
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
1788
Advantage
58
Jiangsu aikang biomedical research and development co., LTD
Tel
025-66110311 13155353615
Email
qzhang@aikonchem.com
Country
China
ProdList
15527
Advantage
58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
Tel
18081075745
Email
chemflowtech@sina.com
Country
China
ProdList
1886
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
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58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58

568544-03-6, 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDERelated Search:


  • GSTO1-IN-1
  • 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
  • GSTO1 inhibitor 1
  • Acetamide, 2-chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]-
  • 2-Chloro-N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)acetamide
  • 2-Chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]acetamide
  • GSTs,GSTO1IN1,Glutathione transferases,inhibit,Inhibitor,Gutathione S-transferase,GSTO1 IN 1,GSTO-1-IN-1
  • 568544-03-6