ChemicalBook > CAS DataBase List > 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE

2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE

Product Name
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
CAS No.
568544-03-6
Chemical Name
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
Synonyms
GSTO1-IN-1;GSTO1 inhibitor 1;2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE;2-Chloro-N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)acetamide;2-Chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]acetamide;Acetamide, 2-chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]-;GSTs,GSTO1IN1,Glutathione transferases,inhibit,Inhibitor,Gutathione S-transferase,GSTO1 IN 1,GSTO-1-IN-1
CBNumber
CB1774579
Molecular Formula
C10H12Cl2N2O3S
Formula Weight
311.18
MOL File
Mol file
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2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Property

storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0042397
Product name
GSTO1-IN-1
Purity
99.12%
Packaging
100mg
Price
$380
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0058363
Product name
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
Purity
95.00%
Packaging
1G
Price
$692.46
Updated
2021/12/16
AK Scientific
Product number
0184CM
Product name
2-Chloro-N-[4-chloro-3-(dimethylsulfamoyl)phenyl]acetamide
Packaging
2.5g
Price
$784
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0058363
Product name
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
Purity
95.00%
Packaging
2.5G
Price
$932.6
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0058363
Product name
2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
Purity
95.00%
Packaging
5G
Price
$1114.58
Updated
2021/12/16
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2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Chemical Properties,Usage,Production

Biological Activity

GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with IC50 of 31 nM.

in vitro

GSTO1-IN-1 (C1-27) potently inhibits GSTO1 enzyme activity with an IC 50 value of 31 nM. GSTO1-IN-1 also potently competes with 5-chloromethylfluorescein diacetate (CMFDA) for binding to recombinant protein, as well as endogenous GSTO1 in the milieu of a soluble proteome. HCT116 cells treated with GSTO1-IN-1 also show a decrease in cell viability in a dose-dependent manner. GSTO1-IN-1 inhibits the clonogenic survival of HCT116 cells at sub-micromolar concentrations.

target

IC50: 31 nM (GSTO1)

2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE Suppliers

China 15 Ukraine 2 United States 5 Global 22
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
Advantage
58

568544-03-6, 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDERelated Search:


  • GSTO1-IN-1
  • 2-CHLORO-N-(4-CHLORO-3-DIMETHYLSULFAMOYL-PHENYL)-ACETAMIDE
  • GSTO1 inhibitor 1
  • Acetamide, 2-chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]-
  • 2-Chloro-N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)acetamide
  • 2-Chloro-N-[4-chloro-3-[(dimethylamino)sulfonyl]phenyl]acetamide
  • GSTs,GSTO1IN1,Glutathione transferases,inhibit,Inhibitor,Gutathione S-transferase,GSTO1 IN 1,GSTO-1-IN-1
  • 568544-03-6