4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE
- Product Name
- 4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE
- CAS No.
- 14279-91-5
- Chemical Name
- 4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE
- Synonyms
- BW 65-100 (hydrochloride);4-ChlorophenylguanidineHCl;(4-Chlorophenyl)guanidine Hydrochlo;p-Chlorophenylguanidine Hydrochloride;4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE;Chlorhexidine Digluconate EP Impurity E;1-(4-chlorophenyl)guanidine hydrochloride;Chlorhexidine Diacetate Impurity E as Hydrochloride;Chlorhexidine Diacetate EP Impurity E as Hydrochloride;4 Chlorophenylguanidine hydrochloride,4Chlorophenylguanidine hydrochloride
- CBNumber
- CB1779701
- Molecular Formula
- C7H9Cl2N3
- Formula Weight
- 206.07
- MOL File
- 14279-91-5.mol
4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Property
- Melting point:
- 237-238 °C(Solv: water (7732-18-5))
- storage temp.
- Store at RT
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Pale Green
- Water Solubility
- Soluble to 100 mM in water
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 0442
- Product name
- 4-Chlorophenylguanidinehydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 100
- Price
- $210
- Updated
- 2021/12/16
- Product number
- C377740
- Product name
- p-ChlorophenylguanidineHydrochloride
- Packaging
- 25mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 254406
- Product name
- 4-Chlorophenylguanidine hydrochloride
- Packaging
- 100mg
- Price
- $495
- Updated
- 2021/12/16
- Product number
- NUC0002752
- Product name
- 4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.99
- Updated
- 2021/12/16
- Product number
- 35R0008S
- Product name
- N-(4-Chloro-phenyl)-guanidinehydrochloride
- Purity
- 96%
- Packaging
- 100mg
- Price
- $95
- Updated
- 2021/12/16
4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
p-Chlorophenylguanidine Hydrochloride is an reagent used in the synthesis of pyrimidine derivatives as hSMG-1 inhibitors, potential targets for cancer treatment.
Biological Activity
4-chlorophenylguanidine hydrochloride is a potent and selective inhibitor of urokinase [1].urokinase is a serine protease. its primary physiological substrate is plasminogen, which is an inactive form of plasmin. urokinase plays an important role in vascular diseases and cancer.4-chlorophenylguanidine hydrochloride inhibited urokinase and trypsin with ki value of 6.07 μm and 120 μm, respectively [1].
storage
Store at RT
References
[1]. yang h, henkin j, kim kh, et al. selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. j med chem, 1990, 33(11): 2956-2961.
4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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