ChemicalBook > CAS DataBase List > ETHYLMALONIC ACID

ETHYLMALONIC ACID

Product Name: ETHYLMALONIC ACID
CAS No.: 601-75-2
Chemical Name: ETHYLMALONIC ACID
Synonyms: ETHYLMALONIC ACID;2-Ethylmalonicaci;2-Ethylmalonic acid;RARECHEM DK HD C012;EthylmalonicAcid>Malonic acid, ethyl-;2-ethylpropanedioate;Ethyl propoinic acid;Ethylmalonicacid,98%;Ethylmalonic acid 97%
CBNumber: CB1782664
Molecular Formula: C5H8O4
Formula Weight: 132.11
MOL File: 601-75-2.mol

Less

ETHYLMALONIC ACID Property

Melting point:: 112-114 °C (lit.)
Boiling point:: 292.77°C (rough estimate)
Density: 1.5633 (rough estimate)
refractive index: 1.4016 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: pK1:2.90(0);pK2:5.55(+1) (25°C)
color: Off-White
Water Solubility: Soluble in water, methanol (very faint turbidity), and ethanol.
BRN: 774334
CAS DataBase Reference: 601-75-2(CAS DataBase Reference)
NIST Chemistry Reference: Ethylmalonic acid(601-75-2)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29171990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 102687
Product name: Ethylmalonic acid
Purity: 97%
Packaging: 5g
Price: $70.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: 102687
Product name: Ethylmalonic acid
Purity: 97%
Packaging: 50g
Price: $361
Updated: 2025/07/31

TCI Chemical

Product number: E0137
Product name: Ethylmalonic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $89
Updated: 2025/07/31

TCI Chemical

Product number: E0137
Product name: Ethylmalonic Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $357
Updated: 2025/07/31

TRC

Product number: E922020
Product name: Ethylmalonic Acid
Packaging: 5g
Price: $45
Updated: 2021/12/16

Less

ETHYLMALONIC ACID Chemical Properties,Usage,Production

Chemical Properties

white to faintly pink crystalline powder

Uses

Ethylmalonic acid is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.

Definition

ChEBI: Ethylmalonic acid is a dicarboxylic acid obtained by substitution of one of the methylene hydrogens of malonic acid by an ethyl group. It has a role as a human metabolite. It is a dicarboxylic acid and a dicarboxylic fatty acid. It is functionally related to a malonic acid. It is a conjugate acid of an ethylmalonate and an ethylmalonate(2-).

Synthesis

6148-64-7

601-75-2

Step 2: In a 250 mL three-necked flask equipped with a magnetic stirrer, a dosing funnel and a thermometer, monoethyl malonate potassium salt (17.77 g, 104.49 mmol) was dissolved in 18 mL of water. The reaction mixture was cooled in an ice bath and 8 mL of concentrated hydrochloric acid (about 2 mL) was added slowly and dropwise. Upon completion of the reaction, the mixture was filtered to remove the resulting KCl precipitate and the precipitate was washed with ether (3 x 50 mL). The filtrate was separated and the aqueous phase was further extracted with ether (3 x 50 mL). All ether phases were combined, dried with anhydrous MgSO4, filtered and concentrated under reduced pressure to give the colorless oily product ethylmalonic acid (13.45 g, 82% overall yield in two steps).

IC 50

Human Endogenous Metabolite

References

[1] Patent: US6780887, 2004, B1

ETHYLMALONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

3-[1,1'-Biphenyl]-4-yl-1,2,3,4-tetrahydro-1-naphthol 3-(4'-Bromo[1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenol

Less

ETHYLMALONIC ACID Suppliers

Americas 1 Belgium 1 Canada 1 CHINA 112 Europe 2 Germany 7 India 7 Japan 4 Slovakia 1 Switzerland 3 United Kingdom 12 United States 31 USA 1 Global 183

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16075
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
Advantage: 60

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Shanghai Na Qian Chemical Technology Co. Ltd.

Tel: 13598610367
Fax: QQ:2468833170
Email: 2841375912@qq.com
Country: China
ProdList: 2788
Advantage: 52

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Chengdu jingzhihuacheng Chemical Technology Co., Ltd.

Tel: 028-028-37664989 15900794981
Email: jingzhichem@163.com
Country: China
ProdList: 537
Advantage: 55

Nanjing Vital Chemical Co., Ltd.

Tel: 025-87193546 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 9021
Advantage: 60

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9186
Advantage: 65

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Shanghai He Huan Chemical Co., Ltd.

Tel: 021-60345187 13917602471
Fax: 021-60345187
Email: lzz841106@aliyun.com
Country: China
ProdList: 510
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-62971590 18548936886
Fax: 010-62340519
Email: 3462612863@qq.com
Country: China
ProdList: 10063
Advantage: 58

Beijing Minruida Technology Co., Ltd.

Tel: 010-82387566 18001021521;
Fax: 82387566-801
Email: sales@mreda.com.cn
Country: China
ProdList: 10083
Advantage: 58

Changzhou Liren Medical Technology Co. Ltd.

Tel: 0519-85859058 13915836899
Email: 2078957504@qq.com
Country: China
ProdList: 358
Advantage: 58

Nanjing Hengbei Chemicals Co., Ltd.

Tel: +86-25-58393656
Fax: +86-25-58393656
Email: sales@hengbeichem.cn
Country: China
ProdList: 6854
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Henan Weituxi Chemical Technology Co., Ltd.

Tel: 0371-63284658 18135795563
Fax: QQ:2885349392
Email: 2885349392@qq.com
Country: China
ProdList: 9990
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

Shanghai jingkang bioengineering co., ltd.

Tel: 021-54721350 13524668266
Fax: 021-5
Email: 2881505714@qq.com
Country: China
ProdList: 7872
Advantage: 58

ShangHai Anpel Co, Ltd.

Tel: 18501792038 18502138905
Email: shanpel@anpel.com.cn
Country: China
ProdList: 9611
Advantage: 58

DONBOO AMINO ACID COMPANY

Tel: +8618051385538
Email: donboo@donboo.com
Country: China
ProdList: 9363
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Shandong Tianming Biotechnology Development Co. Ltd

Tel: 400-9019001
Country: China
ProdList: 15069
Advantage: 58

Shanghai kadel chemical technology co., LTD

Tel: 021-4007787-550 400-7787-550
Email: 2850202386@qq.com
Country: China
ProdList: 10582
Advantage: 58

Less

View Lastest Price from ETHYLMALONIC ACID manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Ethylmalonic acid 601-75-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-28

Career Henan Chemical Co

Product: ETHYLMALONIC ACID 601-75-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2018-08-13

601-75-2, ETHYLMALONIC ACIDRelated Search:

ETHYLMALONIC ACID DIETHYL ESTER Ethylmalonic acid dimethyl ester Ethanesulfonamide ETHYLDIPHENYLPHOSPHINE DIETHYL DIETHYLMALONATE DIALLYL GLUTARATE Diethyl butylmalonate DIETHYL 2-(2-CYANOETHYL)MALONATE Diethyl benzylmalonate DIETHYLMALONIC ACID DIETHYL DIALLYLMALONATE Dimethyl allylmalonate 2-HEXADECYL-MALONIC ACID Dimethyl diethylmalonate TETRAETHYL 1,1,2,2-ETHANETETRACARBOXYLATE BIS[(12-CROWN-4)METHYL] DODECYLMETHYLMALONATE TRIETHYL 1,1,2-ETHANETRICARBOXYLATE Benzylmalonic acid

2-ethylpropanedioic acid

Ethylpropanedioic acid.

Ethylmalonic acid,97%

Ethylmalonic acid 97%

1,1-Propanedicarboxylic acid

2-Ethylmalonic acid

alpha-Carboxybutyric acid

Malonic acid, ethyl-

Propanedioic acid, ethyl-

ETHYLMALONIC ACID

2-CARBOXY BUTYRIC ACID

RARECHEM DK HD C012

2-ethylpropanedioate

Ethyl propoinic acid

Ethylmalonicacid,98%

EthylmalonicAcid&gt

alpha-Carboxybutyrate

Propanedioic acid, 2-ethyl-

2-Ethylmalonicaci

Ethylmalonic AcidQ: What is Ethylmalonic Acid Q: What is the CAS Number of Ethylmalonic Acid Q: What is the storage condition of Ethylmalonic Acid Q: What are the applications of Ethylmalonic Acid

Ethylmalonic acid, 10 mM in DMSO

601-75-2

CH3CH2CHCO2H2

C2H5CHCO2H2

C2H5CHCOOH2

Carbonyl Compounds

Carboxylic Acids

C1 to C5

Building Blocks

Organic Building Blocks

C1 to C5

Carbonyl Compounds

Carboxylic Acids

Pharmaceutical Intermediates

Miscellaneous

Carboxylic Acid Monomers

Monomers

Polymer Science