1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER
- Product Name
- 1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 177478-49-8
- Chemical Name
- 1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- Methyl 1,2,3,4-Tetrahydroquinoline-6-;Methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate;Methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate 97%;1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER;6-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-, methyl ester;Methyl 1,2,3,4-
tetrahydroquinoline- 6- carboxylate - CBNumber
- CB1793220
- Molecular Formula
- C11H13NO2
- Formula Weight
- 191.23
- MOL File
- 177478-49-8.mol
1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER Property
- Melting point:
- 73-76 °C
- Boiling point:
- 349.4±31.0 °C(Predicted)
- Density
- 1.123±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder
- pka
- 2.60±0.20(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- T
- Risk Statements
- 25-36/37/38
- Safety Statements
- 26-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 702374
- Product name
- Methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $274
- Updated
- 2023/06/20
- Product number
- 702374
- Product name
- Methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate
- Purity
- 97%
- Packaging
- 250mg
- Price
- $83.6
- Updated
- 2023/01/07
- Product number
- B486068
- Product name
- Methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CHM0122260
- Product name
- METHYL 1,2,3,4-TETRAHYDROQUINOLINE-6-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1011.6
- Updated
- 2021/12/16
- Product number
- CHM0122260
- Product name
- METHYL 1,2,3,4-TETRAHYDROQUINOLINE-6-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1210.63
- Updated
- 2021/12/16
1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
38896-30-9
177478-49-8
The general procedure for the synthesis of methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate from methyl 6-quinolinecarboxylate was as follows: carbon-loaded palladium (1.50 g, 10% mass fraction) and ammonium formate (10.5 g, 165 mmol) were added in methanol (20 mL), followed by methyl 6-quinolinecarboxylate (1.20 g, 6.41 mmol). The reaction mixture was stirred at 70°C for 2 hours. Upon completion of the reaction, the synthesis was processed according to the synthesis method of Step 1 of Example 2 to afford the white solid product methyl 1,2,3,4-tetrahydroquinoline-6-carboxylate (1.20 g) in 97.9% yield.
References
[1] Catalysis Science and Technology, 2017, vol. 7, # 10, p. 1981 - 1985
[2] Catalysis Science and Technology, 2018, vol. 8, # 10, p. 2648 - 2653
[3] Patent: CN105524053, 2016, A. Location in patent: Paragraph 0534; 0535; 0536
[4] ACS Catalysis, 2018, vol. 8, # 5, p. 4545 - 4557
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 12, p. 3216 - 3220
1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER Suppliers
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View Lastest Price from 1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER manufacturers
- Product
- 1,2,3,4-TETRAHYDRO-QUINOLINE-6-CARBOXYLIC ACID METHYL ESTER 177478-49-8
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 98%; 99%
- Supply Ability
- 500g； 1kg; 25kg
- Release date
- 2020-01-10