Azido-PEG8-hydrazide
- Product Name
- Azido-PEG8-hydrazide
- CAS No.
- 2353410-11-2
- Chemical Name
- Azido-PEG8-hydrazide
- Synonyms
- Azido-PEG8-hydrazide;1-Azido-3,6,9,12,15,18,21,24-octaoxaheptacosane-27-hydrazide
- CBNumber
- CB18054666
- Molecular Formula
- C19H39N5O9
- Formula Weight
- 481.55
- MOL File
- 2353410-11-2.mol
Azido-PEG8-hydrazide Property
- solubility
- Soluble in Water
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-24118
- Product name
- Azido-PEG8-hydrazideHClSalt
- Purity
- 98%
- Packaging
- 50mg
- Price
- $480
- Updated
- 2021/12/16
Azido-PEG8-hydrazide Chemical Properties,Usage,Production
Description
Azido-PEG8-hydrazide HCl salt is a wter soluble PEG linker containing an azide group and a hydrazide moiety. The hydrophilic PEG spacer increases solubility of a compound in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond.
Uses
Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG8-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG8-hydrazide Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG8-hydrazide Suppliers
- Tel
- 0431-80534353 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 3828
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- 55
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- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
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- 4952
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- 58
- Tel
- +1-5166625404;
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
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- 20405
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- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
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- 32467
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- 58
- Tel
- 18191076804
- asherw9@hotmail.com
- Country
- China
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- 2373
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- 58
- Tel
- 13303867194
- 3001317055@qq.com
- Country
- China
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- 9801
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- 58
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- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
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- 58
- Tel
- 13000000000
- Fax
- jinoupharma@163
- jinoupharma@163.com
- Country
- China
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- 11721
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- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
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- 59936
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- 58
- Tel
- 15841022315
- sales@affinitytech.cn
- Country
- China
- ProdList
- 3000
- Advantage
- 58
View Lastest Price from Azido-PEG8-hydrazide manufacturers
- Product
- Azido-PEG8-hydrazide 2353410-11-2
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-23