Clazakizumab
- Product Name
- Clazakizumab
- CAS No.
- 1236278-28-6
- Chemical Name
- Clazakizumab
- Synonyms
- Clazakizumab;Clazakizumab (anti-IL-6);Research Grade Clazakizumab;Research Grade Clazakizumab(DHC15805)
- CBNumber
- CB18080854
- Formula Weight
- 0
- MOL File
- Mol file
Clazakizumab Chemical Properties,Usage,Production
Uses
Clazakizumab is a monoclonal antibody with high affinity and specificity for the IL-6 (interleukin-6) cytokine. Clazakizumab may be helpful in inhibiting the cytokine response to SARS-CoV-2 in COVID-19. Clazakizumab can be used for the research of psoriatic arthritis (PsA) and renal antibody-mediated rejection[1][2].
IC 50
IL-6
References
[1] Mease PJ, et al. The Efficacy and Safety of Clazakizumab, an Anti-Interleukin-6 Monoclonal Antibody, in a Phase IIb Study of Adults With Active Psoriatic Arthritis. Arthritis Rheumatol. 2016 Sep;68(9):2163-73. DOI:10.1002/art.39700
[2] Vaidya G, et al. Successful Treatment of Severe COVID-19 Pneumonia With Clazakizumab in a Heart Transplant Recipient: A Case Report. Transplant Proc. 2020 Nov;52(9):2711-2714. DOI:10.1016/j.transproceed.2020.06.003
Clazakizumab Preparation Products And Raw materials
Raw materials
Preparation Products
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