Mosunetuzumab
- Product Name
- Mosunetuzumab
- CAS No.
- 1905409-39-3
- Chemical Name
- Mosunetuzumab
- Synonyms
- BTCT-4465A;Mosunetuzumab;Mosunetuzumab (DHC90716);Research Grade Mosunetuzumab;Research Grade Mosunetuzumab(DHC90716)
- CBNumber
- CB18081048
- Formula Weight
- 0
- MOL File
- Mol file
Mosunetuzumab Property
- form
- Liquid
- color
- Colorless to light yellow
Mosunetuzumab Chemical Properties,Usage,Production
Uses
Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs)[1][2].
References
[1] Lihua E Budde, et al. Single-Agent Mosunetuzumab Shows Durable Complete Responses in Patients With Relapsed or Refractory B-Cell Lymphomas: Phase I Dose-Escalation Study. J Clin Oncol. 2022 Feb 10;40(5):481-491. DOI:10.1200/JCO.21.00931
[2] Gregory Z Ferl, et al. A Preclinical Population Pharmacokinetic Model for Anti-CD20/CD3 T-Cell-Dependent Bispecific Antibodies. Clin Transl Sci. 2018 May;11(3):296-304. DOI:10.1111/cts.12535
Mosunetuzumab Preparation Products And Raw materials
Raw materials
Preparation Products
Mosunetuzumab Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58