3-BROMOBENZENE-1,2-DIOL
- Product Name
- 3-BROMOBENZENE-1,2-DIOL
- CAS No.
- 14381-51-2
- Chemical Name
- 3-BROMOBENZENE-1,2-DIOL
- Synonyms
- 3-Bromopyrocatechol;3-Bromocatechol >3-BROMOBENZENE-1,2-DIOL;3-bromo-1,2-benzenediol;1,2-Benzenediol, 3-bromo-;Phloroglucinol Impurity 30;2,3-dihydroxy-broMobenzene;1-Bromo-2,3-dihydroxybenzene;3-BROMOBENZENE-1,2-DIOL ISO 9001：2015 REACH;3-bromobenzene-1,2-diol ( = 3-Bromocatechol)
- CBNumber
- CB1841028
- Molecular Formula
- C6H5BrO2
- Formula Weight
- 189.01
- MOL File
- 14381-51-2.mol
3-BROMOBENZENE-1,2-DIOL Property
- Melting point:
- 40-41℃
- Boiling point:
- 243℃
- Density
- 1.844
- Flash point:
- 101℃
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in organic solvents.
- form
- powder to crystal
- pka
- 8.26±0.10(Predicted)
- color
- White to Gray to Brown
- InChI
- InChI=1S/C6H5BrO2/c7-4-2-1-3-5(8)6(4)9/h1-3,8-9H
- InChIKey
- JPBDMIWPTFDFEU-UHFFFAOYSA-N
- SMILES
- C1(O)=CC=CC(Br)=C1O
- CAS DataBase Reference
- 14381-51-2
Safety
- HS Code
- 2908190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B3710
- Product name
- 3-Bromocatechol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $57
- Updated
- 2025/07/31
- Product number
- B3710
- Product name
- 3-Bromocatechol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $263
- Updated
- 2025/07/31
- Product number
- B678093
- Product name
- 3-Bromobenzene-1,2-diol
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 076031
- Product name
- 3-Bromobenzene-1,2-diol
- Purity
- 95+%
- Packaging
- 10g
- Price
- $315
- Updated
- 2021/12/16
- Product number
- W3132
- Product name
- 3-Bromocatechol
- Packaging
- 5g
- Price
- $176
- Updated
- 2021/12/16
3-BROMOBENZENE-1,2-DIOL Chemical Properties,Usage,Production
Chemical Properties
Needle-like crystals
Uses
3-Bromocatechol, is used as a drug and agrochemicals intermediate, Pharmaceutical intermediate.
Synthesis Reference(s)
Journal of the American Chemical Society, 69, p. 2241, 1947 DOI: 10.1021/ja01201a514
Synthesis
28165-49-3
14381-51-2
The general procedure for the synthesis of 3-bromocatechol from 2-bromo-6-methoxyphenol was as follows: to an anhydrous dichloromethane (40 mL) solution of 2-bromo-6-methoxyphenol (8.00 g, 39.4 mmol) was slowly added boron tribromide (1 M in dichloromethane, 43.1 mmol, 43.0 mL) at -78 °C. The reaction mixture was stirred for 1 hour at room temperature, then poured into ice water and continued to stir for 30 minutes. Subsequently, extraction was performed with dichloromethane (3 x 30 mL). The organic layers were combined, dried with anhydrous magnesium sulfate, and concentrated to give the target product 3-bromocatechol (6.90 g, 93% yield) as a brown oil. Thin layer chromatography (TLC) analysis showed an Rf value of 0.2 (unfolding agent: toluene/ethyl acetate = 9:1). The 1H NMR data of the product were as follows: δH 5.60 (1H, broad single peak, OH), 5.69 (1H, broad single peak, OH), 6.72 (1H, double peak, J=8.1 Hz), 6.87 (1H, double peak, J=1.5,8.1 Hz), 7.00 (1H, double peak, J=1.5,8.1 Hz); 13C NMR data: δC 109.5, 114.9, 121.9, 123.3, 140.3, 144.5.The 1H NMR spectra of the products were in agreement with the literature reports.
References
[1] Organic Letters, 2016, vol. 18, # 15, p. 3726 - 3729
[2] Tetrahedron, 2011, vol. 67, # 34, p. 6308 - 6315
[3] Tetrahedron Letters, 1995, vol. 36, # 36, p. 6413 - 6414
3-BROMOBENZENE-1,2-DIOL Preparation Products And Raw materials
Raw materials
Preparation Products
3-BROMOBENZENE-1,2-DIOL Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from 3-BROMOBENZENE-1,2-DIOL manufacturers
- Product
- 3-BROMOBENZENE-1,2-DIOL 14381-51-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 3-BROMOBENZENE-1,2-DIOL 14381-51-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08
- Product
- 3-BROMOBENZENE-1,2-DIOL 14381-51-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-31