Glibornuride

Product Name: Glibornuride
CAS No.: 26944-48-9
Chemical Name: Glibornuride
Synonyms: N-((3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)carbamoyl)-4-methylbenzenesulfonamide;Glitrim;Ro-6-4563;Glibornurid;Glibornuride;Glibornuride USP/EP/BP;Glibornuride (Mixture of Diastereomers);Glibornuride Solution in Acetonitrile/Water, 1000μg/mL;1-[p-Tolylsulfonyl]-3-[2-endo-hydroxy-3-endo-D-bornyl] urea;1-(3-hydroxy-4,7,7-trimethyl-norbornan-2-yl)-3-(4-methylphenyl)sulfonyl-urea
CBNumber: CB1875191
Molecular Formula: C18H26N2O4S
Formula Weight: 366.47504
MOL File: 26944-48-9.mol

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Glibornuride Property

Melting point:: 192-195° (ethanol-water); also reported as 195-198°
alpha: D +63.8° (ethanol)
Density: 1.1793 (rough estimate)
refractive index: 1.6930 (estimate)
storage temp.: Store at -20°C
solubility: DMSO : 250 mg/mL (682.17 mM; Need ultrasonic)
pka: 5.20±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: G409700
Product name: Glibornuride
Packaging: 10mg
Price: $240
Updated: 2021/12/16

Usbiological

Product number: 164299
Product name: Glibornuride
Packaging: 2.5mg
Price: $355
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0010408
Product name: GLIBORNURIDE
Purity: 95.00%
Packaging: 1MG
Price: $750.75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0010408
Product name: GLIBORNURIDE
Purity: 95.00%
Packaging: 5MG
Price: $1963.5
Updated: 2021/12/16

AvaChem

Product number: 3155
Product name: Glibornuride
Packaging: 25mg
Price: $390
Updated: 2021/12/16

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Glibornuride Chemical Properties,Usage,Production

Originator

Glutril,Roche,W. Germany,1972

Uses

Glibornuride has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. Glibornuride is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus.

Definition

ChEBI: Glibornuride is a monoterpenoid.

Manufacturing Process

2.1 grams of 3-endo-aminoborneol hydrochloride and 2.4 grams of O-methylN-p-toluene-sulfonyl-urea are heated at 125°C for 3 hours with 2 ml of dimethylformamide. After cooling, the reaction mixture is stirred with 100 ml of water for 10 minutes, while a pH of 3.5 is maintained by the addition of a few drops of dilute hydrochloric acid. The precipitate is removed by filtration, washed with water and suspended in 100 ml of water. The suspension is dissolved by the addition of 20 ml of 1 N caustic soda. The alkaline solution is extracted with ether, acidified with dilute hydrochloric acid and filtered. The precipitate is washed with water and recrystallized from alcohol/water to yield 1-(p-toluene-sulfonyl)-3-(2-endo-hydroxy-3-endo-bornyl)-urea having a melting point of 193° to 195°C.

brand name

Glutril (Hoffmann-LaRoche).

Therapeutic Function

Oral hypoglycemic

Glibornuride Preparation Products And Raw materials

Raw materials

Preparation Products

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Glibornuride Suppliers

China 74 Europe 1 Germany 1 India 5 South Korea 1 United States 5 Global 87

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14059
Advantage: 65

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8073
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4121
Advantage: 55

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4515
Advantage: 55

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55827
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 29016
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: 0571-85134551
Fax: 008657185134895
Email: info@afinechem.com
Country: CHINA
ProdList: 15377
Advantage: 58

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View Lastest Price from Glibornuride manufacturers

Dideu Industries Group Limited

Product: Glibornuride 26944-48-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-15

26944-48-9, GlibornurideRelated Search:

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1-[p-Tolylsulfonyl]-3-[2-endo-hydroxy-3-endo-D-bornyl] urea

N-((3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)carbamoyl)-4-methylbenzenesulfonamide

Glibornuride (Mixture of Diastereomers)

Glibornuride

Glitrim

N-[[[(1S,2S,3R,4R)-2-Hydroxyborn-3-yl]amino]carbonyl]-4-methylbenzenesulfonamide

Ro-6-4563

1-(3-hydroxy-4,7,7-trimethyl-norbornan-2-yl)-3-(4-methylphenyl)sulfonyl-urea

1-(6-hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea

1-(6-hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonyl-urea

1-(3-hydroxy-4,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea

Glibornurid

Benzenesulfonamide, N-[[[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl]amino]carbonyl]-4-methyl-

Glibornuride Solution in Acetonitrile/Water, 1000μg/mL

Glibornuride USP/EP/BP

Inhibitor,K channel,KcsA,blocker ATP,sensitive,Glibornuride,inhibit,Parsley,Streptozotocin,Antidiabetic,Potassium Channel

N-(((1S,2S,3R,4S)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)carbamoyl)-4-methylbenzenesulfonamide

26944-48-9

C18H26N2O4S

Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds