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oxeladin

Product Name
oxeladin
CAS No.
468-61-1
Chemical Name
oxeladin
Synonyms
oxeladin;oxeladin USP/EP/BP;IQADUMSPOQKAAO-UHFFFAOYSA-N;2-(β-1Diethylaminoethoxy)ethyl diethylphenyl acetate;2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate;2-[2-(Diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate;α,α-Diethylbenzeneacetic acid 2-(2-diethylaminoethoxy)ethyl ester;2-Ethyl-2-phenylbutyric acid 2-[2-(diethylamino)ethoxy]ethyl ester;Benzeneacetic acid, α,α-diethyl-, 2-[2-(diethylamino)ethoxy]ethyl ester
CBNumber
CB1875328
Molecular Formula
C20H33NO3
Formula Weight
335.48
MOL File
468-61-1.mol
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oxeladin Property

Melting point:
25°C
Boiling point:
bp0.5 150°; bp0.1 140°
Density 
1.0720 (rough estimate)
refractive index 
1.5614 (estimate)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0016280
Product name
OXELADIN
Purity
95.00%
Packaging
5MG
Price
$498.48
Updated
2021/12/16
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oxeladin Chemical Properties,Usage,Production

Originator

Silopentol,Schulte,W. Germany ,1970

Uses

Oxeladin can be used in ex vivo modeling of drug efficacy in rare metastatic urachal carcinoma.

Definition

ChEBI: Oxeladin is an alkylbenzene.

Manufacturing Process

Preparation of Diethylphenylacetonitrile: 25 grams of sodium was dissolved in 300 ml liquid ammonia containing 0.3 gram ferric chloride and 59 grams phenylacetonitrile was added slowly with stirring. After about 15 minutes a cooled solution of 80 grams of ethyl chloride in 200 ml dry ether was added and the mixture stirred for 1 hour. The ammonia was then allowed to evaporate, water added and the ether layer separated, dried, concentrated and the residual oil distilled in vacuo to yield diethylphenylacetonitrile as an oil, BP 85°C/1 mm.
Preparation of Diethylphenylacetic Acid: 46 grams of the foregoing nitrile was added to 140 ml ethylene glycol containing 36 grams potassium hydroxide and the mixture refluxed with stirring for about 20 hours. The mixture was diluted with water, extracted with light petroleum (BP 60° to 80°C) to remove traces of impurities and then acidified to yield diethylphenylacetic acid which was recrystallized from dilute ethanol (40% v/v ethanol in water).
Preparation of 2-(β-Chloroethoxy)Ethyl Diethylphenylacetate: 19.2 grams of the foregoing acid was added to a solution of 4 grams of sodium hydroxide in 40 ml ethylene glycol. 28.6 grams β,β'-dichlorodiethyl ether was added and the mixture refluxed for 1 hour. After removal of solvent under reduced pressure, 150 ml water was added to the residue and the product extracted with ether. The ethereal solution was dried, concentrated and the residue distilled in vacuo to yield the product as an oil, BP 140°C/0.7 mm.
Preparation of 2-(β-Diethylaminoethoxy)Ethyl Diethylphenylacetate: A mixture of 21 grams of 2-(β-chloroethoxy)ethyl diethylphenylacetate and 14 grams diethylamine was heated under pressure in a sealed tube at 140°C for 5 hours. After cooling, the mixture was dissolved in dilute hydrochloric acid and extracted with ether to remove traces of neutral impurities. The acid layer was then made alkaline with 10% w/v sodium hydroxide solution with cooling, and re-extracted with two portions of ether. The ether extract was dried, the ether distilled off and the residue distilled in vacuo to yield the product as an oil, BP 140°C/0.1 mm.

Therapeutic Function

Antitussive

oxeladin Preparation Products And Raw materials

Raw materials

Preparation Products

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oxeladin Suppliers

BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
29831
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28180
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
18192627656
Fax
+86-29-88380327
Email
1012@dideu.com
Country
China
ProdList
3911
Advantage
58
Wuhan pengyin Pharmaceutical Co., Ltd
Tel
13163333255
Email
1939328613@qq.com
Country
China
ProdList
395
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
029-81148696 18161915376
Email
1040@dideu.com
Country
China
ProdList
10009
Advantage
58
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View Lastest Price from oxeladin manufacturers

Dideu Industries Group Limited
Product
oxeladin 468-61-1
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100Tons min
Release date
2021-06-10
Shaanxi Dideu Medichem Co. Ltd
Product
Oxeladin 468-61-1
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-04-24

468-61-1, oxeladinRelated Search:


  • 2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate
  • oxeladin
  • 2-(β-1Diethylaminoethoxy)ethyl diethylphenyl acetate
  • 2-Ethyl-2-phenylbutyric acid 2-[2-(diethylamino)ethoxy]ethyl ester
  • α,α-Diethylbenzeneacetic acid 2-(2-diethylaminoethoxy)ethyl ester
  • IQADUMSPOQKAAO-UHFFFAOYSA-N
  • 2-[2-(Diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate
  • Benzeneacetic acid, α,α-diethyl-, 2-[2-(diethylamino)ethoxy]ethyl ester
  • oxeladin USP/EP/BP
  • 468-61-1
  • 468-68-1