ChemicalBook > CAS DataBase List > 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

Product Name
2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)
CAS No.
57781-14-3
Chemical Name
2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)
Synonyms
Topicon;THS 201;Haloart;Ccris 2685;Einecs 260-951-4;halopredone acetate;Halopredone 17,21-diacetate;17,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione;17α,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione;17,21-Bis(acetyloxy)-2-bromo-6beta,9-difluoro-11beta-hydroxypregna-1,4-diene-3,20-dione
CBNumber
CB1902921
Molecular Formula
C25H29BrF2O7
Formula Weight
559.39
MOL File
57781-14-3.mol
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2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Property

Melting point:
290-292° (dec)
alpha 
D24 -36° (c = 1 in chloroform)
Density 
1.3611 (rough estimate)
refractive index 
1.3760 (estimate)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0002886
Product name
2-BROMO-6BETA,9-DIFLUORO-11BETA,17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 17,21-DI(ACETATE)
Purity
95.00%
Packaging
5MG
Price
$505.75
Updated
2021/12/16
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2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Chemical Properties,Usage,Production

Originator

Topicon,Pierrel,Italy,1983

Uses

Anti-inflammatory (topical).

Definition

ChEBI: Halopredone acetate is an organic molecular entity.

Manufacturing Process

100 ml of a 70% hydrofluoric acid aqueous solution were cooled to -10°C in a polyethylene flask equipped with electromagnetic stirrer. 10 g of 2-bromo-6β- fluoro-17α,21-dihydroxy-9β, 11β-oxido-pregna-1,4-diene-3,20-dione-17,21- diacetate were added under stirring during 15 minutes. After 0.5 hour the reaction mixture was precipitated in water and ammonia. The solid was collected by filtration, washed with water and dried to a constant weight, giving about 9.5 g of 2-bromo-6β,9α-difluoro-11β,17α,21 -trihydroxypregna- 1,4-diene-3,20-dione-17,21-diacetate.

Therapeutic Function

Topical antiinflammatory

2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Preparation Products And Raw materials

Raw materials

Preparation Products

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2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) Suppliers

HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
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Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54

57781-14-3, 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)Related Search:


  • Haloart
  • halopredone acetate
  • 2-bromo-6beta,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)
  • Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6β,11β)-
  • THS 201
  • Topicon
  • 17,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione
  • 17α,21-Bis(acetyloxy)-2-bromo-6β,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione
  • 17,21-Bis(acetyloxy)-2-bromo-6-beta,9-difluoro-11-beta-hydroxypregna-1,4-dien-3,20-dione
  • 17,21-Bis(acetyloxy)-2-bromo-6beta,9-difluoro-11beta-hydroxypregna-1,4-diene-3,20-dione
  • Ccris 2685
  • Einecs 260-951-4
  • Halopredone 17,21-diacetate
  • Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-2-bromo-6,9-difluoro-11-hydroxy-, (6beta,11beta)-
  • 57781-14-3
  • C25H29BrF2O7