glucose 1-(dihydrogen phosphate)
- Product Name
- glucose 1-(dihydrogen phosphate)
- CAS No.
- 59-56-3
- Chemical Name
- glucose 1-(dihydrogen phosphate)
- Synonyms
- GLC-1-P;glucose-1P;Glucose-1-phosphate;alpha-D-glucose-1-P;a-Glucose-1-phosphate;Glucose monophosphate.;α-D-glucose1-phosphate;alpha-glucose-1-phosphate;D-glucose-alpha-1-phosphate;HXXFSFRBOHSIMQ-VFUOTHLCSA-N
- CBNumber
- CB1906439
- Molecular Formula
- C6H13O9P
- Formula Weight
- 260.13
- MOL File
- 59-56-3.mol
glucose 1-(dihydrogen phosphate) Property
- Boiling point:
- 603.0±65.0 °C(Predicted)
- Density
- 1.90±0.1 g/cm3(Predicted)
- solubility
- Soluble (water), slightly soluble (ethanol)
- form
- Solid
- pka
- pKa: 6.504(25°C)
- color
- White to off-white
- optical activity
- Alpha type +120
- EPA Substance Registry System
- .alpha.-D-Glucopyranose, 1-(dihydrogen phosphate) (59-56-3)
Safety
- RIDADR
- 1759
- HazardClass
- 8
- PackingGroup
- III
N-Bromosuccinimide Price
- Product number
- 167838
- Product name
- Glucose-1-Phosphate
- Packaging
- 100Tests
- Price
- $772
- Updated
- 2021/12/16
- Product number
- CRB0004385
- Product name
- ALPHA-GLUCOSE-1-PHOSPHATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.3
- Updated
- 2021/12/16
- Product number
- 824
- Product name
- α-D-1-13C-Glucopyranosyl1-phosphate
- Packaging
- 0.1g
- Price
- $550
- Updated
- 2021/12/16
glucose 1-(dihydrogen phosphate) Chemical Properties,Usage,Production
Uses
α-D-Glucose-1-phosphate is an important intermediate in sugar metabolism, functioning as a glycosyl donor in glycosyl transfer reactions and participating in glycogen synthesis and degradation through the action of phosphorylases[1].
Definition
ChEBI: A D-glucopyranose 1-phosphate in which the anomeric centre has alpha-configuration.
IC 50
Human Endogenous Metabolite
Purification Methods
Two litres of a 5% aqueous solution of the phosphate are purified by adjusting the pH to 3.5 with glacial acetic acid (+ 3g of charcoal) and filtering. An equal volume of EtOH is added, the pH is adjusted to 8.0 (glass electrode) and the solution is stored at 3o overnight. The precipitate is filtered off, dissolved in 1.2L of distilled water, filtered and an equal volume of EtOH is added. After standing at 0o overnight, the crystals are collected at the centrifuge and washed with 95% EtOH, then absolute EtOH, ethanol/diethyl ether (1:1), and diethyl ether. [Sutherland & Wosilait, J Biol Chem 218 459 1956.] Its barium salt can be crystallised from water and EtOH. Heavy metal impurities are removed by passage of an aqueous solution (ca 1%) through an Amberlite IR-120 column (in the appropriate H+, Na+ or K+ forms). Di-K salt crystallises as a dihydrate from EtOH. [see McGready Biochemical Preparations 4 63 1955.] [Beilstein 17/8 V 247.]
References
[1] Nihira T, et al. 2-O-α-D-glucosylglycerol phosphorylase from Bacillus selenitireducens MLS10 possessing hydrolytic activity on β-D-glucose 1-phosphate. PLoS One. 2014 Jan 22;9(1):e86548. DOI:10.1371/journal.pone.0086548
glucose 1-(dihydrogen phosphate) Preparation Products And Raw materials
Raw materials
Preparation Products
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