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thiocolchicine

Product Name: thiocolchicine
CAS No.: 2730-71-4
Chemical Name: thiocolchicine
Synonyms: NSC 186301;thiocolchicine;thiocholchicine;10-Thiocolchicine;Thiocolchicine, 10 mM in DMSO;Thiocolchicoside EP Impurity B;10-Demethoxy-10-methylthiocolchicine;(S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one;(S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one;N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide
CBNumber: CB1926071
Molecular Formula: C22H25NO5S
Formula Weight: 415.5
MOL File: 2730-71-4.mol

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thiocolchicine Property

Melting point:: 193℃
alpha: D20 -221°
Boiling point:: 729.1±60.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: soluble10mg/mL, clear
pka: 14.75±0.40(Predicted)
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
RIDADR: UN 1544PSN1 6.1 / PGI
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

H340May cause genetic defects

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0954
Product name: Thiocolchicine
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $41.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0954
Product name: Thiocolchicine
Purity: ≥97% (HPLC)
Packaging: 25mg
Price: $168
Updated: 2025/07/31

Cayman Chemical

Product number: 17427
Product name: Thiocolchicine
Purity: ≥98%
Packaging: 5mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 17427
Product name: Thiocolchicine
Purity: ≥98%
Packaging: 10mg
Price: $71
Updated: 2024/03/01

Cayman Chemical

Product number: 17427
Product name: Thiocolchicine
Purity: ≥98%
Packaging: 25mg
Price: $166
Updated: 2024/03/01

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thiocolchicine Chemical Properties,Usage,Production

Chemical Properties

Bright Yellow Solid

Uses

A muscle relaxant.

Biochem/physiol Actions

Thiocolchicine is an antimitotic alkaloid and apoptosis inducer that inhibits tubulin polymerization and microtubule assembly.

thiocolchicine Preparation Products And Raw materials

Raw materials

Preparation Products

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2730-71-4, thiocolchicineRelated Search:

thiocolchicine

thiocholchicine

(S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one

(S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one

10-Demethoxy-10-methylthiocolchicine

10-Thiocolchicine

N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide

N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-triMethoxy-10-(Methylthio)-9-oxobenzo[a]heptalen-7-yl]acetaMide

NSC 186301

(S)-N-(1,2,3-trimethoxy-10-(methylthio)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide

Thiocolchicoside EP Impurity B

Acetamide, N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-

breast,LoVo/DX,MDR-positive,Microtubule/Tubulin,inhibit,MCF-7,leukemia,Colchicine,Apoptosis,BALB/3T3,cancer,A-549,LoVo,Thiocolchicine,Analogue,Inhibitor

N-[(7S,12aRa)-1,2,3-trimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (thiocolchicine)

Thiocolchicine, 10 mM in DMSO

2730-71-4

Intermediates & Fine Chemicals

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