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thiocolchicine

Product Name
thiocolchicine
CAS No.
2730-71-4
Chemical Name
thiocolchicine
Synonyms
NSC 186301;thiocolchicine;thiocholchicine;10-Thiocolchicine;Thiocolchicine, 10 mM in DMSO;Thiocolchicoside EP Impurity B;10-Demethoxy-10-methylthiocolchicine;(S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one;(S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one;N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide
CBNumber
CB1926071
Molecular Formula
C22H25NO5S
Formula Weight
415.5
MOL File
2730-71-4.mol
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thiocolchicine Property

Melting point:
193℃
alpha 
D20 -221°
Boiling point:
729.1±60.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble10mg/mL, clear
pka
14.75±0.40(Predicted)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
RIDADR 
UN 1544PSN1 6.1 / PGI
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

H340May cause genetic defects

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0954
Product name
Thiocolchicine
Purity
≥97% (HPLC)
Packaging
5mg
Price
$41.1
Updated
2025/07/31
Sigma-Aldrich
Product number
SML0954
Product name
Thiocolchicine
Purity
≥97% (HPLC)
Packaging
25mg
Price
$168
Updated
2025/07/31
Cayman Chemical
Product number
17427
Product name
Thiocolchicine
Purity
≥98%
Packaging
5mg
Price
$38
Updated
2024/03/01
Cayman Chemical
Product number
17427
Product name
Thiocolchicine
Purity
≥98%
Packaging
10mg
Price
$71
Updated
2024/03/01
Cayman Chemical
Product number
17427
Product name
Thiocolchicine
Purity
≥98%
Packaging
25mg
Price
$166
Updated
2024/03/01
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thiocolchicine Chemical Properties,Usage,Production

Chemical Properties

Bright Yellow Solid

Uses

A muscle relaxant.

Biochem/physiol Actions

Thiocolchicine is an antimitotic alkaloid and apoptosis inducer that inhibits tubulin polymerization and microtubule assembly.

thiocolchicine Preparation Products And Raw materials

Raw materials

Preparation Products

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thiocolchicine Suppliers

Canada 1 China 70 France 1 India 5 United States 9 Global 86
Alsachim SAS
Tel
--
Fax
--
Email
sales@alsachim.com
Country
France
ProdList
424
Advantage
0

2730-71-4, thiocolchicineRelated Search:


  • thiocolchicine
  • thiocholchicine
  • (S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one
  • (S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one
  • 10-Demethoxy-10-methylthiocolchicine
  • 10-Thiocolchicine
  • N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide
  • N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-triMethoxy-10-(Methylthio)-9-oxobenzo[a]heptalen-7-yl]acetaMide
  • NSC 186301
  • (S)-N-(1,2,3-trimethoxy-10-(methylthio)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide
  • Thiocolchicoside EP Impurity B
  • Acetamide, N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-
  • breast,LoVo/DX,MDR-positive,Microtubule/Tubulin,inhibit,MCF-7,leukemia,Colchicine,Apoptosis,BALB/3T3,cancer,A-549,LoVo,Thiocolchicine,Analogue,Inhibitor
  • N-[(7S,12aRa)-1,2,3-trimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (thiocolchicine)
  • Thiocolchicine, 10 mM in DMSO
  • 2730-71-4
  • Intermediates & Fine Chemicals
  • Pharmaceuticals