Sinomenine N-oxide
- Product Name
- Sinomenine N-oxide
- CAS No.
- 1000026-77-6
- Chemical Name
- Sinomenine N-oxide
- Synonyms
- Sinomenine N-oxide;Sinomenine N-oxide, 10 mM in DMSO;Sinomenine N oxide,Sinomenine Noxide;Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, 17-oxide,;Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, 17-oxide, (9α,13α,14α)-
- CBNumber
- CB19308106
- Molecular Formula
- C19H23NO5
- Formula Weight
- 345.4
- MOL File
- 1000026-77-6.mol
Sinomenine N-oxide Property
- Melting point:
- 155-156 °C(Solv: methanol (67-56-1))
- pka
- 9.24±0.40(Predicted)
- form
- Solid
- color
- White to off-white
Sinomenine N-oxide Chemical Properties,Usage,Production
Description
Sinomenine N-oxide is a plant extract with anti-angiogenic, anti-inflammatory and anti-rheumatic properties. It is also an inhibitor of NO production with an IC50 value of 23.04 μM.
Uses
Sinomenine N-oxide has anti-angiogenic, anti-inflammatory and anti-rheumatic effects. Sinomenine N-oxide is also a NO production inhibitor, with an IC50 value of 23.04 μM[1][2][3].
References
[1] Liu WJ, et al. Network pharmacology approach to elucidate possible action mechanisms of Sinomenii Caulis for treating osteoporosis. J Ethnopharmacol. 2020 Jul 15;257:112871. DOI:10.1016/j.jep.2020.112871
[2] Zeng HL, et al. New N-oxide alkaloids from the stems of Sinomenium acutum. Fitoterapia. 2023 Mar;165:105404. DOI:10.1016/j.fitote.2022.105404
[3] Li Q, et al. Metabolic mechanism and anti-inflammation effects of sinomenine and its major metabolites N-demethylsinomenine and sinomenine-N-oxide. Life Sci. 2020 Nov 15;261:118433. DOI:10.1016/j.lfs.2020.118433
Sinomenine N-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
Sinomenine N-oxide Suppliers
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58