ChemicalBook > CAS DataBase List > 5-chloro-1-methyl-1H-indole-2,3-dione

5-chloro-1-methyl-1H-indole-2,3-dione

Product Name: 5-chloro-1-methyl-1H-indole-2,3-dione
CAS No.: 60434-13-1
Chemical Name: 5-chloro-1-methyl-1H-indole-2,3-dione
Synonyms: Einecs 262-231-5;5-Chloro-1-methylisatin;5-Chloro-1-methylindole-2,3-dione;5-Chloro-1-methyl-2,3-indolinedione;5-Chloro-1-methylindoline-2,3-dione;1-Methyl-5-chloroindoline-2,3-dione;5-chloro-1-methyl-1H-indole-2,3-dione;1H-Indole-2,3-dione, 5-chloro-1-methyl-;5-chloro-1-methyl-1H-indole-2,3-dione(SALTDATA: FREE)
CBNumber: CB1931190
Molecular Formula: C9H6ClNO2
Formula Weight: 195.6
MOL File: 60434-13-1.mol

Less

5-chloro-1-methyl-1H-indole-2,3-dione Property

Melting point:: 175.0 to 179.0 °C
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
color: Orange to Red
λmax: 426nm(EtOH)(lit.)

Less

Safety

HS Code: 2933998090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: C3195
Product name: 5-Chloro-1-methylisatin
Purity: >98.0%(GC)
Packaging: 200mg
Price: $129
Updated: 2025/07/31

TCI Chemical

Product number: C3195
Product name: 5-Chloro-1-methylisatin
Purity: >98.0%(GC)
Packaging: 1g
Price: $386
Updated: 2025/07/31

TRC

Product number: C602150
Product name: 5-Chloro-1-methylindoline-2,3-dione
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC143306
Product name: 5-Chloro-1-methylindoline-2,3-dione
Packaging: 500mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC143306
Product name: 5-Chloro-1-methylindoline-2,3-dione
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Less

5-chloro-1-methyl-1H-indole-2,3-dione Chemical Properties,Usage,Production

Synthesis Reference(s)

Journal of Medicinal Chemistry, 39, p. 5072, 1996 DOI: 10.1021/jm960603e

Synthesis

872305-97-0

60434-13-1

GENERAL METHODS: A mixture of N-methyl-2-oxo-N-phenylacetamide (0.4 mmol) and ferric chloride (10 mol%) was dissolved in 2 mL of dimethylsulfoxide (DMSO), and the reaction was stirred for 1.5 h at 100 °C under air atmosphere. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was cooled to room temperature, diluted with water and extracted with ethyl acetate. The organic layers were combined, washed with saturated sodium chloride solution and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product. Purification of the crude product by rapid column chromatography on silica gel (petroleum ether/ethyl acetate = 10:1) afforded 1-methyldihydroindole-2,3-dione as a red solid (60 mg, 93% yield).

References

[1] RSC Advances, 2015, vol. 5, # 125, p. 103280 - 103283
[2] Tetrahedron Letters, 2016, vol. 57, # 1, p. 39 - 42
[3] Synlett, 2016, vol. 27, # 8, p. 1292 - 1296
[4] Journal of the American Chemical Society, 2010, vol. 132, # 26, p. 8900 - 8902
[5] Chemistry - A European Journal, 2007, vol. 13, # 4, p. 1032 - 1046

5-chloro-1-methyl-1H-indole-2,3-dione Preparation Products And Raw materials

Raw materials

Preparation Products

Less

5-chloro-1-methyl-1H-indole-2,3-dione Suppliers

Americas 1 China 41 Europe 1 India 2 Japan 1 The Netherlands 1 United Kingdom 1 United States 5 Global 53

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Chengdu Forest Science and Technology Development Co., Ltd.

Tel: 18030648795
Fax: 028-61777050
Email: sales@cdforestchem.com
Country: China
ProdList: 1999
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
Fax: 86(512)5235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 4169
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai YuYuan Pharmaceutical Co., Ltd.

Tel: 13052276172
Fax: 13052276172
Email: product@yuyuanpharm.com
Country: China
ProdList: 493
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Biokitchen

Tel: 021-021-021-31663258 13795219287
Fax: 021-31663258
Email: donghuanwen@126.com
Country: China
ProdList: 8816
Advantage: 58

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

TCI Chemicals

Tel: 021-67121386, 800-988-0390
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 5391
Advantage: 58

Henan Alfa Chemical Co., Ltd

Tel: +8615838112936
Email: alfa10@alfachem.cn
Country: China
ProdList: 12921
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9941
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

CHG Opto-Electronic Corporation Limited

Tel: 2537653158 16621191650
Fax: QQ 2537653158
Email: 2537653158@qq.com
Country: China
ProdList: 7301
Advantage: 58

Zhengzhou Alpha Chemical Co. LTD

Tel: 0371-0371-53732842 13383863444
Fax: QQ：3002612166
Email: 3002612166@qq.com
Country: China
ProdList: 9996
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Hebei Weite Medical Technology Co., Ltd

Tel: 13180081292 13180081292
Email: contact@wetogethermed.com
Country: China
ProdList: 7949
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Hubei Moco Chemical Co., Ltd.

Tel: 18627753421; 18627756402
Fax: QQ：3001051413
Email: 3001051413@qq.com
Country: China
ProdList: 20319
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-81136151 17392212881
Email: 1095@dideu.com
Country: China
ProdList: 10001
Advantage: 58

Tanmo Quality Inspection Technology Co., Ltd.

Tel: 4008-099-669
Email: 23419001name@qq.com
Country: CHINA
ProdList: 6043
Advantage: 58

Nanjing SynTitan Pharmaceutical Co., Ltd.

Tel: 25-57027686 17372956142
Email: li_lan@syntitan.com
Country: China
ProdList: 5807
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 17715136450
Email: 2439673774@qq.com
Country: China
ProdList: 15647
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 14580
Advantage: 58

ShenZhen H&D Pharmaceutical Technology Co., LTD

Tel: +8618627948422
Email: sale@hdimpurity.com
Country: China
ProdList: 3681
Advantage: 58

Guangzhou Keyuan Instrument Equipment Co., Ltd.

Tel: 13725272260
Country: CHINA
ProdList: 113
Advantage: 58

Beijing Pubiao Technology Co., Ltd.

Tel: 18618179058
Country: CHINA
ProdList: 122
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Shanghai Shize Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shizezjp@163.com
Country: CHINA
ProdList: 6174
Advantage: 58

Rhenbo (Shanghai) Biochemical Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6333
Advantage: 58

Beijing Luyuan Bird Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 15810802415@139.com
Country: CHINA
ProdList: 6750
Advantage: 58

Shanghai Machine Pure Industrial Co., Ltd.

Tel: --
Fax: --
Email: 3245176082@qq.com
Country: CHINA
ProdList: 6800
Advantage: 58

Shanghai Wowu Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shhebio@126.com
Country: CHINA
ProdList: 6137
Advantage: 58

Shanghai Jingke Chemical Technology Co., Ltd.

Tel: --
Fax: --
Email: jingkehuaxue@163.com
Country: CHINA
ProdList: 6141
Advantage: 58

Shanghai Caiyou Industrial Co., Ltd.

Tel: --
Fax: --
Email: 15821073967@163.com
Country: CHINA
ProdList: 6748
Advantage: 58

60434-13-1, 5-chloro-1-methyl-1H-indole-2,3-dioneRelated Search:

5-Chloroindoline 1-(2-BROMOETHYL)-5-CHLORO-1H-INDOLE-2,3-DIONE 5-CHLORO-1-[3-(TRIFLUOROMETHYL)BENZYL]-1H-INDOLE-2,3-DIONE 5-chloro-1-methyl-1H-indole-2,3-dione 5-CHLORO-1-(6-CHLOROHEXYL)-1H-INDOLE-2,3-DIONE 5-CHLORO-1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 5-CHLORO-2,3-DIOXO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER AKOS BBS-00001016 5-chloro-1-ethyl-2,3-dihydro-1H-indole-2,3-dione 5-CHLORO-1-(4-CHLOROBENZYL)-1H-INDOLE-2,3-DIONE AKOS BBS-00001011 5-CHLORO-1-(2,6-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE AKOS BBS-00001010 AKOS BBS-00001022 5-chloro-1-(thiophen-2-ylmethyl)-2,3-dihydro-1H-indole-2,3-dione AKOS BBS-00001023 AKOS BBS-00001019 1-(3-BROMOPROPYL)-5-CHLORO-1H-INDOLE-2,3-DIONE

5-Chloro-1-methylisatin

5-chloro-1-methyl-1H-indole-2,3-dione

1-Methyl-5-chloroindoline-2,3-dione

5-Chloro-1-methylindoline-2,3-dione

Einecs 262-231-5

5-chloro-1-methyl-1H-indole-2,3-dione(SALTDATA: FREE)

1H-Indole-2,3-dione, 5-chloro-1-methyl-

5-Chloro-1-methyl-2,3-indolinedione

5-Chloro-1-methylindole-2,3-dione

60434-13-1