noxytiolin
- Product Name
- noxytiolin
- CAS No.
- 15599-39-0
- Chemical Name
- noxytiolin
- Synonyms
- Gynaflex;Noxyflex S;noxytiolin;Noxythiolin;Noxytioline;Noxythioline;1-(Hydroxymethyl)-3-methylthiourea;(methylamino-λsup4sup-sulfanylidyne)methylamino]methanol
- CBNumber
- CB1933871
- Molecular Formula
- C3H8N2OS
- Formula Weight
- 120.17
- MOL File
- 15599-39-0.mol
noxytiolin Property
- Melting point:
- 88-90°
- Boiling point:
- 203.7±42.0 °C(Predicted)
- Density
- 1.223±0.06 g/cm3(Predicted)
- pka
- 13.45±0.10(Predicted)
Safety
- Toxicity
- LD50 orally in mice: >3 g/kg (Aebi, Hafstetter)
N-Bromosuccinimide Price
- Product number
- API0003640
- Product name
- NOXYTIOLIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.38
- Updated
- 2021/12/16
noxytiolin Chemical Properties,Usage,Production
Originator
Noxyflex,Geistlich,UK,1964
Definition
ChEBI: Noxytiolin is a member of thioureas.
Manufacturing Process
400 g methyl thiourea and 2.5 g NaHCO3 are dissolved in 400 ml formaldehyde solution of 35% concentration. After having been left at ordinary temperature for 2 to 3 hours, the solution is adjusted with dilute HCl to pH 7 to 7.5. After the reaction mixture had been left overnight at 15°C some of the final product crystallized and was filtered off using a Buchner funnel. The mother liquor was concentrated by evaporation in vacuo at a bath-temperature of 30°C. The crystals obtained were again collected by filtration using a Buchner funnel and were combined with the first crystalline fraction and dried in vacuo at ordinary temperature. Yield of pure substance 400 g; melting point 84°C to 86°C.
Therapeutic Function
Antifungal
noxytiolin Preparation Products And Raw materials
Raw materials
Preparation Products
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