2-aminoethanesulphonamide monohydrochloride
- Product Name
- 2-aminoethanesulphonamide monohydrochloride
- CAS No.
- 89756-60-5
- Chemical Name
- 2-aminoethanesulphonamide monohydrochloride
- Synonyms
- Taurinamide HCl;TaurylaMide Hydrochloride;ST-31-84;Taurylamide;2-AMinoethanesulfonaMide, HCl;2-AMinoethanesulfonaMide(HCl ForM);2-Aminoethanesulfomide hydrochloride;2-aminoethylsulfonamide hydrochloride ;2-Aminoethanesulphonamide hydrochloride;2-aminoethanesulphonamide monohydrochloride
- CBNumber
- CB1939606
- Molecular Formula
- C2H9ClN2O2S
- Formula Weight
- 160.62306
- MOL File
- 89756-60-5.mol
2-aminoethanesulphonamide monohydrochloride Property
- Melting point:
- 133 °C
- Boiling point:
- 315°
- Flash point:
- 150°
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- InChI
- InChI=1S/C2H8N2O2S.ClH/c3-1-2-7(4,5)6;/h1-3H2,(H2,4,5,6);1H
- InChIKey
- DGUVEYAZTOUCEJ-UHFFFAOYSA-N
- SMILES
- C(S(N)(=O)=O)CN.[H]Cl
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T007845
- Product name
- TaurinamideHydrochloride
- Packaging
- 500mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- J90596
- Product name
- 2-AminoethanesulfonamideHCl
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 027073
- Product name
- 2-Aminoethanesulfonamide hydrochloride
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- X5933
- Product name
- 2-AminoethanesulfonamideHCl
- Packaging
- 1g
- Price
- $61
- Updated
- 2021/12/16
- Product number
- 027073
- Product name
- 2-Aminoethanesulfonamide hydrochloride
- Packaging
- 5g
- Price
- $149
- Updated
- 2021/12/16
2-aminoethanesulphonamide monohydrochloride Chemical Properties,Usage,Production
Description
2-Aminoethanesulphonamide monohydrochloride is a perovskite with a hexagonal shape. It has been shown to interact with the pharmacophore of the enzyme cytochrome P450, and it has been optimized for the reaction by altering its structure. This product is soluble in gaseous form, but can also be used as a solid. 2-Aminoethanesulphonamide monohydrochloride has an absorption maximum at 325 nm and emits fluorescence at 420 nm. It is used in devices that detect ionizing radiation.
Uses
Taurinamide is a derivative of Taurolidine; a drug with antimicrobial and antiendotoxic properties.
Synthesis
4443-23-6
89756-60-5
General Method B: Deprotection of phthalimidosulfonamides to prepare the corresponding primary amines. The following procedure applies to the synthesis of aminoethanesulfonamides or aminopropanesulfonamides. The synthesis of 2-aminoethanesulfonamide hydrochloride from 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanesulfonamide was carried out as follows: 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanesulfonamide (1.52 g, 6.78 mmol) was suspended in ethanol (30 ml), and refluxed by heating. Subsequently, 64% hydrazine hydrate solution (0.36 ml, 7.5 mmol) was slowly added to the reaction system. After 3 hours of reaction, precipitate generation was observed and the precipitate was removed by filtration. The filtrate was concentrated to dryness and the residue was dissolved in water (150 ml). The aqueous phase suspension was acidified with concentrated hydrochloric acid and filtered to remove hydrochloric acid and insoluble impurities. The filtrate was again concentrated to dryness and the crude product was recrystallized by solvent mixing of ethanol/water (9:1) to give 764 mg (64% yield) of the target product 2-aminoethanesulfonamide hydrochloride as a solid. The product was characterized by 1H-NMR (D2O) with chemical shifts δ (ppm) of 3.62-3.55 (m, 2H) and 3.51-3.44 (m, 2H).
References
[1] Patent: EP2077263, 2009, A1. Location in patent: Page/Page column 15-16
[2] Journal of Medicinal Chemistry, 2016, vol. 59, # 11, p. 5462 - 5470
[3] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 3, p. 474 - 483
2-aminoethanesulphonamide monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-aminoethanesulphonamide monohydrochloride manufacturers
- Product
- 2-aminoethanesulphonamide monohydrochloride 89756-60-5
- Price
- US $1.50/g
- Min. Order
- 1g
- Purity
- 99.0% Min
- Supply Ability
- 100 Tons
- Release date
- 2025-09-25
- Product
- 2-aminoethanesulphonamidehydrochloride 89756-60-5
- Price
- US $1.50/g
- Min. Order
- 1g
- Purity
- 99.0% Min
- Supply Ability
- 10 Tons
- Release date
- 2025-06-24
- Product
- 2-aminoethanesulphonamide monohydrochloride 89756-60-5
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-24