ChemicalBook > CAS DataBase List > 2-Methoxy-5-fluoro-4-aminopyrimidine

2-Methoxy-5-fluoro-4-aminopyrimidine

Product Name
2-Methoxy-5-fluoro-4-aminopyrimidine
CAS No.
1993-63-1
Chemical Name
2-Methoxy-5-fluoro-4-aminopyrimidine
Synonyms
5-Fluoro-2-MethoxypyriMidin-4-aMine;5-Fluoro-2-methoxy-4-pyrimidinamine;4-AMINO-5-FLUORO-2-METHOXYPYRIMIDINE;2-Methoxy-5-fluoro-4-aminopyrimidine;4-Pyrimidinamine, 5-fluoro-2-methoxy;5-Fluoro-2-methoxy-pyrimidin-4-ylamine;4-Amino-5-fluoro-2-methoxypyrimidine >4-Pyrimidinamine, 5-fluoro-2-methoxy- (9CI);2-Methoxy-5-fluoro-4-aminopyrimidine ISO 9001：2015 REACH;2-methoxy-5-fluoro-4-aminopyrimidine (intermediate of flucytosine)
CBNumber
CB1946996
Molecular Formula
C5H6FN3O
Formula Weight
143.12
MOL File
1993-63-1.mol
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2-Methoxy-5-fluoro-4-aminopyrimidine Property

Melting point:
193 °C
Boiling point:
278.9±43.0 °C(Predicted)
Density 
1.345±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
powder to crystal
pka
3.63±0.10(Predicted)
color 
White to Almost white
InChI
InChI=1S/C5H6FN3O/c1-10-5-8-2-3(6)4(7)9-5/h2H,1H3,(H2,7,8,9)
InChIKey
BYALTIIVASWNSY-UHFFFAOYSA-N
SMILES
C1(OC)=NC=C(F)C(N)=N1
CAS DataBase Reference
1993-63-1
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2125
Product name
4-Amino-5-fluoro-2-methoxypyrimidine
Purity
>99.0%(T)
Packaging
5g
Price
$317
Updated
2025/07/31
TRC
Product number
F599353
Product name
5-Fluoro-2-methoxypyrimidin-4-amine
Packaging
100mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
PC906580
Product name
4-Amino-5-fluoro-2-methoxypyrimidine
Purity
95%
Packaging
1g
Price
$105
Updated
2021/12/16
AK Scientific
Product number
Z4372
Product name
5-Fluoro-2-methoxypyrimidin-4-amine
Packaging
10g
Price
$191
Updated
2021/12/16
Apolloscientific
Product number
PC906580
Product name
4-Amino-5-fluoro-2-methoxypyrimidine
Purity
95%
Packaging
5g
Price
$230
Updated
2021/12/16
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2-Methoxy-5-fluoro-4-aminopyrimidine Chemical Properties,Usage,Production

Synthesis

1801-06-5

1993-63-1

General procedure for the synthesis of 5-fluoro-2-methoxy-4-fluoropyrimidinamine using 2-methoxy-4-chloro-5-fluoropyrimidine as starting material: 32.5 g of 2-methoxy-4-chloro-5-fluoropyrimidine (compound of formula III) was added to 170 g of a 10 wt% solution of isopropanol in ammonia, heated to 40-60 °C, and the reaction was stirred for 3-5 hours. After completion of the reaction, it was naturally cooled to room temperature and the solid product was collected by filtration. The solid was washed with isopropanol and dried to give 27.2 g of 5-fluoro-2-methoxy-4-pyrimidinamine (compound of formula II, white solid) in 95.0% molar yield and 99.0% HPLC purity.

References

[1] Patent: CN105272922, 2016, A. Location in patent: Paragraph 0038; 0039; 0040

2-Methoxy-5-fluoro-4-aminopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Methoxy-5-fluoro-4-aminopyrimidine Suppliers

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View Lastest Price from 2-Methoxy-5-fluoro-4-aminopyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Methoxy-5-fluoro-4-aminopyrimidine 1993-63-1
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-26
Hebei Yanxi Chemical Co., Ltd.
Product
2-Methoxy-5-fluoro-4-aminopyrimidine 1993-63-1
Price
US $1.00/kg
Min. Order
1kg
Purity
98.00%
Supply Ability
20tons
Release date
2023-09-08

1993-63-1, 2-Methoxy-5-fluoro-4-aminopyrimidine Related Search:

2,4-Diamino-6-hydroxypyrimidine 5-Fluoro-4-hydrazinyl-2-methoxypyrimidine 2-Methoxy-5-fluoro-4-aminopyrimidine 5-fluoropyrimidin-4-amine 5-FLUORO-2-HYDROXYPYRIMIDINE

  • 2-Methoxy-5-fluoro-4-aminopyrimidine
  • 4-Pyrimidinamine, 5-fluoro-2-methoxy- (9CI)
  • 4-AMINO-5-FLUORO-2-METHOXYPYRIMIDINE
  • 2-methoxy-5-fluoro-4-aminopyrimidine (intermediate of flucytosine)
  • 5-Fluoro-2-methoxy-4-pyrimidinamine
  • 5-Fluoro-2-MethoxypyriMidin-4-aMine
  • 5-Fluoro-2-methoxy-pyrimidin-4-ylamine
  • 4-Pyrimidinamine, 5-fluoro-2-methoxy
  • 4-Amino-5-fluoro-2-methoxypyrimidine &gt
  • 2-Methoxy-5-fluoro-4-aminopyrimidine ISO 9001：2015 REACH
  • 1993-63-1
  • C5H6N3OF
  • (intermediate of flucytosine)
  • PYRIMIDINE