ChemicalBook > CAS DataBase List > 2,4-Diamino-6-hydroxypyrimidine

2,4-Diamino-6-hydroxypyrimidine

Product Name
2,4-Diamino-6-hydroxypyrimidine
CAS No.
56-06-4
Chemical Name
2,4-Diamino-6-hydroxypyrimidine
Synonyms
1956-6-4;2,6-DIAMINOPYRIMIDIN-4-OL;DAHP;2,6-Diaminopyrimidin-4(1H)-one;2,6-DIAMINO-4-PYRIMIDINOL;2,6-diamino-1H-pyrimidin-4-one;2,6-DIAMINO-4-HYDROXYPYRIMIDINE;4(3H)-pyrimidinone, 2,6-diamino-;9-60-9;NSC 9302
CBNumber
CB0174912
Molecular Formula
C4H6N4O
Formula Weight
126.12
MOL File
56-06-4.mol
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2,4-Diamino-6-hydroxypyrimidine Property

Melting point:
285-286 °C (dec.) (lit.)
Boiling point:
234.22°C (rough estimate)
Density 
1.3659 (rough estimate)
refractive index 
1.7990 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
10.61±0.50(Predicted)
form 
Fine Crystalline Powder
color 
White to cream
Sensitive 
Light Sensitive
Merck 
14,2981
BRN 
125006
InChIKey
SWELIMKTDYHAOY-UHFFFAOYSA-N
CAS DataBase Reference
56-06-4(CAS DataBase Reference)
NIST Chemistry Reference
4(1H)-pyrimidinone, 2,6-diamino-(56-06-4)
EPA Substance Registry System
2,6-Diamino-4(1H)-pyrimidinone (56-06-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D1321
Product name
2,4-Diamino-6-hydroxypyrimidine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$76
Updated
2024/03/01
Alfa Aesar
Product number
B21240
Product name
2,4-Diamino-6-hydroxypyrimidine, 96%
Packaging
25g
Price
$28.65
Updated
2024/03/01
Alfa Aesar
Product number
B21240
Product name
2,4-Diamino-6-hydroxypyrimidine, 96%
Packaging
100g
Price
$68.65
Updated
2024/03/01
Cayman Chemical
Product number
81260
Product name
2,4-Diamino-6-hydroxypyrimidine
Purity
≥98%
Packaging
1g
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
81260
Product name
2,4-Diamino-6-hydroxypyrimidine
Purity
≥98%
Packaging
5g
Price
$50
Updated
2024/03/01
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2,4-Diamino-6-hydroxypyrimidine Chemical Properties,Usage,Production

Description

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.

Chemical Properties

White Solid

Uses

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical]

Uses

It stands at the beginning of the enzyme-catalyzed cascade that starts with this seven-carbon carbohydrate and ends with the aromatic amino acids phenylalanine, tyrosine, and tryptophan

Uses

2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.

storage

+4°C

Purification Methods

It recrystallises from H2O. [Beilstein 25 III/IV 3642.]

2,4-Diamino-6-hydroxypyrimidine Preparation Products And Raw materials

Raw materials

Guanidine nitrate Methyl cyanoacetate

Preparation Products

2,4-DIAMINO-6-MERCAPTOPYRIMIDINE 2,6-DIAMINO-4-METHOXY PYRIMIDINE
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2,4-Diamino-6-hydroxypyrimidine Suppliers

Americas 1 Austria 1 Belgium 3 Canada 2 China 351 Europe 5 France 3 Germany 11 India 50 Italy 1 Japan 6 Russia 2 Slovakia 1 South Korea 2 Switzerland 4 The Netherlands 3 Ukraine 2 United Kingdom 22 United States 65 USA 1 Global 536
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4321
Advantage
58
Shijiazhuang Feizi Chemical Technology Co. LTD
Tel
0311-85957988 18633001459
Email
sales@feizichem.com
Country
China
ProdList
55
Advantage
58
Changzhou Gangtong Chemical Co., Ltd
Tel
13506120961
Email
1871415438@163.com
Country
China
ProdList
25
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5875
Advantage
58
Jilin Lianben Technology Development Co., Ltd
Tel
13756693631
Fax
0432-62601618
Email
sunting@lianben.com
Country
China
ProdList
46
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
667
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
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View Lastest Price from 2,4-Diamino-6-hydroxypyrimidine manufacturers

Hebei Mojin Biotechnology Co.,Ltd
Product
2,4-Diamino-6-hydroxypyrimidine 56-06-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-20
Anhui Ruihan Technology Co., Ltd
Product
2,4-Diamino-6-hydroxypyrimidine 56-06-4
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000t/year
Release date
2023-09-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
2,4-Diamino-6-hydroxypyrimidine 56-06-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

56-06-4, 2,4-Diamino-6-hydroxypyrimidineRelated Search:

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  • TIMTEC-BB SBB004252
  • 2,4-DIAMINOPYRIMIDIN-6-OL
  • 2,4-DIAMINO-6-HYDROXYPYRIMIDINE
  • 2,4-DIAMINO-6-PYRIMIDINOL
  • 2,4-DIAMINO-6(1H)-PYRIMIDINONE
  • 2,6-DIAMINO-4-PYRIMIDINOL
  • 2,6-DIAMINO-4-PYRIMIDINONE
  • 2,6-DIAMINOPYRIMIDIN-4-OL
  • 2,6-DIAMINO-4(1H)-PYRIMIDINONE
  • 2,6-DIAMINO-4-HYDROXYPYRIMIDINE
  • AURORA KA-376
  • DAHP
  • AKOS MSC-0109
  • 2,6-Diamino-4-Hydroxyprimidine
  • 2,6-diamino-1H-pyrimidin-4-one
  • 2-4-DIAMINO6HYDROXY PYRIMID
  • 2,4- two-6- aMinohydroxy pyriMidine
  • 2,4-DiaMino-6-hydroxypyriMidine 96%
  • 2,4-DiaMino-6-hydroxypyriMidine, 97+%
  • 3-methylidene-1,5-benzodioxepine
  • Pemetrexed Impurity 16
  • 4(3H)-pyrimidinone, 2,6-diamino-
  • InChI=1/C4H6N4O/c5-2-1-3(9)8-4(6)7-2/h1H,(H5,5,6,7,8,9
  • 1956-6-4
  • 2,4-Diamino-6-hydroxypyrimidiine
  • 4(1H)-Pyrimidinone, 2,6-diamino- (8CI,9CI)
  • 2,6-Diaminopyrimidin-4-one
  • 6-Aminoisocytosine
  • NSC 44914
  • NSC 680818
  • NSC 9302
  • 2,4-Diamino-6-hydroxy
  • 2,4-diaminohypoxanthine
  • 2,6-Diamino-1H-pyrimidin-4-on
  • 2,4-Diamino-6. -Hydroxypyimidine
  • 2,6-DIAMINO-3H-PYRIMIDIN-4-ONE
  • 4(1H)-Pyrimidinone, 2,6-diamino
  • 2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol, 2,6-Diamino-4-pyrimidinone
  • 2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol
  • 2,4-Diamino-6-pyrimidinone
  • 2,6-Diamino-3,4-dihydropyrimidine-4-one
  • 2,6-Diamino-4(3H)-pyrimidinone
  • 2,6-Diaminopyrimidin-4(1H)-one
  • 2,4-Diamino-6-hydroxypyrimidine,2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol, 2,6-Diamino-4-pyrimidinone
  • 4-DiaMino-6-hydroxypyriMidine
  • 2,4-Diamino-6-hydroxypyrimidine,96%
  • 2,4-DIAMINO-6-HYDROXYPYRIDIMIDINE
  • 6-Hydroxy-2,4-diaminopyrimidine
  • 2,4-Diamino-6-hydroxypyrimidine &gt
  • 2,4-Diamino-6-hydroxypyrimidine ISO 9001：2015 REACH
  • 2,4-Diamino-6-hydroxypyrimidine,56-06-4
  • NSC 18522
  • NSC18522
  • NSC-18522
  • Minoxidil Impurity 19
  • 2,4-Diamino-6-hydroxypyrimidine(98.60%)
  • 9-60-9
  • 2.4-Diamino-6-pyrimidone