ChemicalBook > CAS DataBase List > 2,4-Diamino-6-hydroxypyrimidine

2,4-Diamino-6-hydroxypyrimidine

Product Name
2,4-Diamino-6-hydroxypyrimidine
CAS No.
56-06-4
Chemical Name
2,4-Diamino-6-hydroxypyrimidine
Synonyms
1956-6-4;2,6-DIAMINOPYRIMIDIN-4-OL;DAHP;2,6-Diaminopyrimidin-4(1H)-one;2,6-DIAMINO-4-PYRIMIDINOL;2,6-diamino-1H-pyrimidin-4-one;2,6-DIAMINO-4-HYDROXYPYRIMIDINE;4(3H)-pyrimidinone, 2,6-diamino-;9-60-9;NSC 9302
CBNumber
CB0174912
Molecular Formula
C4H6N4O
Formula Weight
126.12
MOL File
56-06-4.mol
More
Less

2,4-Diamino-6-hydroxypyrimidine Property

Melting point:
285-286 °C (dec.) (lit.)
Boiling point:
234.22°C (rough estimate)
Density 
1.3659 (rough estimate)
refractive index 
1.7990 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
10.61±0.50(Predicted)
form 
Fine Crystalline Powder
color 
White to cream
Sensitive 
Light Sensitive
Merck 
14,2981
BRN 
125006
InChIKey
SWELIMKTDYHAOY-UHFFFAOYSA-N
CAS DataBase Reference
56-06-4(CAS DataBase Reference)
NIST Chemistry Reference
4(1H)-pyrimidinone, 2,6-diamino-(56-06-4)
EPA Substance Registry System
2,6-Diamino-4(1H)-pyrimidinone (56-06-4)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29335995
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
D1321
Product name
2,4-Diamino-6-hydroxypyrimidine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$76
Updated
2024/03/01
Alfa Aesar
Product number
B21240
Product name
2,4-Diamino-6-hydroxypyrimidine, 96%
Packaging
25g
Price
$28.65
Updated
2024/03/01
Alfa Aesar
Product number
B21240
Product name
2,4-Diamino-6-hydroxypyrimidine, 96%
Packaging
100g
Price
$68.65
Updated
2024/03/01
Cayman Chemical
Product number
81260
Product name
2,4-Diamino-6-hydroxypyrimidine
Purity
≥98%
Packaging
1g
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
81260
Product name
2,4-Diamino-6-hydroxypyrimidine
Purity
≥98%
Packaging
5g
Price
$50
Updated
2024/03/01
More
Less

2,4-Diamino-6-hydroxypyrimidine Chemical Properties,Usage,Production

Description

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.

Chemical Properties

White Solid

Uses

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical]

Uses

It stands at the beginning of the enzyme-catalyzed cascade that starts with this seven-carbon carbohydrate and ends with the aromatic amino acids phenylalanine, tyrosine, and tryptophan

Uses

2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.

storage

+4°C

Purification Methods

It recrystallises from H2O. [Beilstein 25 III/IV 3642.]

2,4-Diamino-6-hydroxypyrimidine Preparation Products And Raw materials

Raw materials

Guanidine nitrate Methyl cyanoacetate

Preparation Products

2,4-DIAMINO-6-MERCAPTOPYRIMIDINE 2,6-DIAMINO-4-METHOXY PYRIMIDINE
More
Less

2,4-Diamino-6-hydroxypyrimidine Suppliers

Americas 1 Austria 1 Belgium 3 Canada 2 China 360 Europe 5 France 3 Germany 11 India 49 Italy 1 Japan 6 Russia 2 Slovakia 1 South Korea 2 Switzerland 4 The Netherlands 3 Ukraine 2 United Kingdom 22 United States 65 USA 1 Global 544
GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Manvi Biopharma Pvt. Ltd
Tel
--
Fax
--
Email
info@manvibiopharma.com
Country
India
ProdList
8
Advantage
58
LOUIS PHARMACEUTICALS PVT.LTD.
Tel
--
Fax
--
Email
louisibd@louispharmaindia.com
Country
India
ProdList
11
Advantage
58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
Biosyn Research Chemicals
Tel
--
Fax
--
Email
info@biosyn.in
Country
India
ProdList
1340
Advantage
58
Saflik Pharma LLP
Tel
--
Fax
--
Email
hamzaansari@saflikpharma.com
Country
India
ProdList
12
Advantage
58
Anand Agencies
Tel
--
Fax
--
Email
en@gmail.com
Country
India
ProdList
2332
Advantage
58
Medkem Laboratories
Tel
--
Fax
--
Email
info@medkem.com
Country
India
ProdList
295
Advantage
58
Pharma Affiliates
Tel
--
Fax
--
Email
@pharmaffiliates.com
Country
India
ProdList
6754
Advantage
58
Dr Chindepalli
Tel
--
Fax
--
Email
Dr.Chindepalli@gmail.com
Country
India
ProdList
486
Advantage
58
Anant Pharmaceuticals Pvt. ltd
Tel
--
Fax
--
Email
info@anantlabs.com
Country
India
ProdList
736
Advantage
58
Sai Quest Syn. Ltd
Tel
--
Fax
--
Country
India
ProdList
268
Advantage
58
Oceanic Pharmachem Pvt. Ltd.
Tel
--
Fax
--
Email
info@oceanicpharmachem.com
Country
India
ProdList
2005
Advantage
58
Opulent Pharma
Tel
--
Fax
--
Country
India
ProdList
810
Advantage
58
Chemit Laboratories
Tel
--
Fax
--
Country
India
ProdList
287
Advantage
58
Saradhi Organics
Tel
--
Fax
--
Email
sales@saradhiorganics.com
Country
India
ProdList
183
Advantage
58
Vyas Bio Life Sciences Pvt. Ltd
Tel
--
Fax
--
Country
India
ProdList
1213
Advantage
58
Telangana Pharmatech
Tel
--
Fax
--
Country
India
ProdList
34
Advantage
58
Genuine Lab Products
Tel
--
Fax
--
Email
sales@genuinelab.in
Country
India
ProdList
26
Advantage
58
VASIN BIO LIFE SCIENCES PVT LTD
Tel
--
Fax
--
Email
info@vasinbio.com
Country
India
ProdList
2092
Advantage
58
HiMedia Laboratories
Tel
--
Fax
--
Email
o@himedialabs.com
Country
India
ProdList
1841
Advantage
58
Avigya Biosciences Pvt., Ltd.
Tel
--
Fax
--
Email
info@avigyabio.com
Country
India
ProdList
115
Advantage
58
Rajbhushan Pharmaceuticals Pvt., Ltd.
Tel
--
Fax
--
Email
bhushan@rajbhushanpharma.com
Country
India
ProdList
26
Advantage
58
Molecraft LifeSciences Pvt Ltd
Tel
--
Fax
--
Email
info@molecraft.com
Country
India
ProdList
757
Advantage
0
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
CHEMSWORTH
Tel
--
Fax
--
Email
info@chemsworth.com
Country
India
ProdList
6700
Advantage
30
Dr. Jagath Reddy's Heterocyclics
Tel
--
Fax
--
Email
jagathreddy@usa.net
Country
India
ProdList
3886
Advantage
42
More
Less

View Lastest Price from 2,4-Diamino-6-hydroxypyrimidine manufacturers

Hebei Mojin Biotechnology Co.,Ltd
Product
2,4-Diamino-6-hydroxypyrimidine 56-06-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-20
Anhui Ruihan Technology Co., Ltd
Product
2,4-Diamino-6-hydroxypyrimidine 56-06-4
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000t/year
Release date
2023-09-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
2,4-Diamino-6-hydroxypyrimidine 56-06-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

56-06-4, 2,4-Diamino-6-hydroxypyrimidineRelated Search:

Triclosan 1,3-Dihydroxyacetone 4,4'-Methylenedianiline Iminodiacetic acid 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL 4-Hydroxy-6-aminopyrimidine 1-Hydroxyethylidene-1,1-diphosphonic acid 1,3-Diaminoguanidine monohydrochloride Iminodiacetonitrile 4-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester Methyl 4-(4-oxobutyl)benzoate N-[4-[3-(2,6-DiaMino-1,4-dihydro-4-oxo-5-pyriMidinyl)-3-oxopropyl]benzoyl]-L-glutaMic Acid 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid 3-Buten-1-ol PeMetrexed IMpurity D PeMetrexed EP IMpurity C Methyl 4-bromobenzoate Benzoic acid, 4-(1-methyl-3-oxopropyl)-, methyl ester (9CI)

  • TIMTEC-BB SBB004252
  • 2,4-DIAMINOPYRIMIDIN-6-OL
  • 2,4-DIAMINO-6-HYDROXYPYRIMIDINE
  • 2,4-DIAMINO-6-PYRIMIDINOL
  • 2,4-DIAMINO-6(1H)-PYRIMIDINONE
  • 2,6-DIAMINO-4-PYRIMIDINOL
  • 2,6-DIAMINO-4-PYRIMIDINONE
  • 2,6-DIAMINOPYRIMIDIN-4-OL
  • 2,6-DIAMINO-4(1H)-PYRIMIDINONE
  • 2,6-DIAMINO-4-HYDROXYPYRIMIDINE
  • AURORA KA-376
  • DAHP
  • AKOS MSC-0109
  • 2,6-Diamino-4-Hydroxyprimidine
  • 2,6-diamino-1H-pyrimidin-4-one
  • 2-4-DIAMINO6HYDROXY PYRIMID
  • 2,4- two-6- aMinohydroxy pyriMidine
  • 2,4-DiaMino-6-hydroxypyriMidine 96%
  • 2,4-DiaMino-6-hydroxypyriMidine, 97+%
  • 3-methylidene-1,5-benzodioxepine
  • Pemetrexed Impurity 16
  • 4(3H)-pyrimidinone, 2,6-diamino-
  • InChI=1/C4H6N4O/c5-2-1-3(9)8-4(6)7-2/h1H,(H5,5,6,7,8,9
  • 1956-6-4
  • 2,4-Diamino-6-hydroxypyrimidiine
  • 4(1H)-Pyrimidinone, 2,6-diamino- (8CI,9CI)
  • 2,6-Diaminopyrimidin-4-one
  • 6-Aminoisocytosine
  • NSC 44914
  • NSC 680818
  • NSC 9302
  • 2,4-Diamino-6-hydroxy
  • 2,4-diaminohypoxanthine
  • 2,6-Diamino-1H-pyrimidin-4-on
  • 2,4-Diamino-6. -Hydroxypyimidine
  • 2,6-DIAMINO-3H-PYRIMIDIN-4-ONE
  • 4(1H)-Pyrimidinone, 2,6-diamino
  • 2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol, 2,6-Diamino-4-pyrimidinone
  • 2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol
  • 2,4-Diamino-6-pyrimidinone
  • 2,6-Diamino-3,4-dihydropyrimidine-4-one
  • 2,6-Diamino-4(3H)-pyrimidinone
  • 2,6-Diaminopyrimidin-4(1H)-one
  • 2,4-Diamino-6-hydroxypyrimidine,2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol, 2,6-Diamino-4-pyrimidinone
  • 4-DiaMino-6-hydroxypyriMidine
  • 2,4-Diamino-6-hydroxypyrimidine,96%
  • 2,4-DIAMINO-6-HYDROXYPYRIDIMIDINE
  • 6-Hydroxy-2,4-diaminopyrimidine
  • 2,4-Diamino-6-hydroxypyrimidine &gt
  • 2,4-Diamino-6-hydroxypyrimidine ISO 9001：2015 REACH
  • 2,4-Diamino-6-hydroxypyrimidine,56-06-4
  • NSC 18522
  • NSC18522
  • NSC-18522
  • Minoxidil Impurity 19
  • 2,4-Diamino-6-hydroxypyrimidine(98.60%)
  • 9-60-9
  • 2.4-Diamino-6-pyrimidone