4-Hydroxy-6-aminopyrimidine

Product Name: 4-Hydroxy-6-aminopyrimidine
CAS No.: 1193-22-2
Chemical Name: 4-Hydroxy-6-aminopyrimidine
Synonyms: 6-AMINOPYRIMIDIN-4-OL;6-AMINOPYRIMIDIN-4(3H)-ONE;4-AMINO-6-HYDROXYPYRIMIDINE;NSC 19868;4-AMino-6-pyriMidinol;6-Amino-4-pyrimidinol;6-Amino-3H-pyrimidin-4-one;6-amino-1H-pyrimidin-4-one;6-Amino-4(1H)-pyrimidinone;6-Amino-4(3H)-pyrimidinone
CBNumber: CB4135450
Molecular Formula: C4H5N3O
Formula Weight: 111.1
MOL File: 1193-22-2.mol

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4-Hydroxy-6-aminopyrimidine Property

Melting point:: 262-264°C
Boiling point:: 227.5±43.0 °C(Predicted)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO
form: Solid
pka: 10.04±0.40(Predicted)
color: White
BRN: 112429
InChI: InChI=1S/C4H5N3O/c5-3-1-4(8)7-2-6-3/h1-2H,(H3,5,6,7,8)
InChIKey: HFMLLTVIMFEQRE-UHFFFAOYSA-N
SMILES: C1=NC(N)=CC(=O)N1
CAS DataBase Reference: 1193-22-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-41
Safety Statements: 26-36-39
HazardClass: IRRITANT
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2439
Product name: 4-Amino-6-hydroxypyrimidine
Purity: >98.0%(T)
Packaging: 1g
Price: $32
Updated: 2025/07/31

TCI Chemical

Product number: A2439
Product name: 4-Amino-6-hydroxypyrimidine
Purity: >98.0%(T)
Packaging: 5g
Price: $137
Updated: 2025/07/31

TRC

Product number: A611665
Product name: 4-Amino-6-hydroxypyrimidine
Packaging: 100mg
Price: $55
Updated: 2021/12/16

TRC

Product number: A629075
Product name: 6-Aminopyrimidin-4-ol
Packaging: 5g
Price: $1100
Updated: 2021/12/16

Usbiological

Product number: A1380-24
Product name: 6-Aminopyrimidin-4-ol
Packaging: 500mg
Price: $425
Updated: 2021/12/16

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4-Hydroxy-6-aminopyrimidine Chemical Properties,Usage,Production

Chemical Properties

White Solid

Synthesis

1004-40-6

1193-22-2

Step 2: 2-mercapto-4-amino-6-hydroxypyridine (mass ratio 1:15) was added to 25% ammonia, followed by the addition of activated nickel and titanium dioxide, wherein the molar ratio of 2-mercapto-4-amino-6-hydroxypyridine, activated nickel and titanium dioxide was 1:4:1.5. The mixture was heated to 90°C and the reaction was carried out at reflux for 5 hours. Upon completion of the reaction, the activated nickel and titanium dioxide were removed by thermal filtration. The filtrate was cooled to room temperature and the solid product was precipitated. The solid was washed with 30 mL of water and dried at 40 °C to afford 4-amino-6-hydroxypyrimidine in 98.4% yield.

References

[1] Patent: CN105218554, 2016, A. Location in patent: Paragraph 0023
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 9, p. 1918 - 1929
[3] Patent: EP1406911, 2016, B1. Location in patent: Paragraph 00382; 00383

4-Hydroxy-6-aminopyrimidine Preparation Products And Raw materials

Raw materials

Ethanol 4,6-Dichloropyrimidine RANEY NICKEL Ethyl acetate Hydrochloric acid HYDRAZINE Diisopropyl ether Ammonia

Preparation Products

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4-Hydroxy-6-aminopyrimidine Suppliers

Americas 1 Canada 2 China 145 Europe 4 Germany 3 India 4 Japan 1 The Netherlands 1 United Kingdom 11 United States 26 Global 198

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View Lastest Price from 4-Hydroxy-6-aminopyrimidine manufacturers

Dideu Industries Group Limited

Product: 4-Hydroxy-6-aminopyrimidine 1193-22-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-09

Career Henan Chemical Co

Product: 4-Hydroxy-6-aminopyrimidine 1193-22-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 90%-99.9%
Supply Ability: 500kg
Release date: 2019-07-12

Career Henan Chemical Co

Product: 4-Hydroxy-6-aminopyrimidine 1193-22-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 90%-99.9%
Supply Ability: 500kg
Release date: 2019-07-09

1193-22-2, 4-Hydroxy-6-aminopyrimidineRelated Search:

2,5-Diamino-4,6-dihydropyrimidine hemisulfate salt 5-Bromo-4,6-dihydroxypyrimidine 2-Methylthio-4,6-pyrimidinedione 2,4-Diamino-6-hydroxypyrimidine ,98% 4-Hydroxy-6-aminopyrimidine ETRIMFOS 5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE 2-AMINO-4,6-DIHYDROXY-5-NITROPYRIMIDINE 2-Amino-4,6-dihydroxypyrimidine 2,4,5-Triamino-6-chloropyrimidine hydrochloride 4,5-DIAMINO-6-HYDROXYPYRIMIDINE SULFATE 2-Amino-4,6-dimethoxypyrimidine 6-Aminothiouracil 2-Cyanoamino-4,6-dihydroxypyrimidine 4,6-Dihydroxy-2-methylpyrimidine 4,5-DIAMINO-6-HYDROXYPYRIMIDINE HEMISULFATE 2,5-Diamino-4,6-dihydroxy-pyrimidine 4,6-DIHYDROXY-5-NITROPYRIMIDINE

4(3H)-Pyrimidinone, 6-amino-

4-AMINO-6-HYDROXYPYRIMIDINE

6-AMINOPYRIMIDIN-4(3H)-ONE

6-AMINOPYRIMIDIN-4-OL

6-amino-1H-pyrimidin-4-one

4(1H)-Pyrimidinone, 6-amino- (8CI,9CI)

6-Amino-3H-pyrimidin-4-one

4(1H)-Pyrimidinone, 6-amino-

6-AMINO-4-HYDROXYPYRIMIDINE

6-amino-4(1H)-Pyrimidinone (8CI,9CI)

4-Hydroxy-6-aminopyrimidine

4-Amino-6(1H)-oxopyrimidine

6-Amino-3,4-dihydropyrimidine-4-one

6-Amino-4(1H)-pyrimidinone

6-Amino-4(3H)-pyrimidinone

6-Aminopyrimidine-4(3H)-one

4-AMino-6-pyriMidinol

NSC 19868

6-AMino-4-pyriMidinol 4-AMino-6-hydroxypyriMidine

6-azanyl-1H-pyrimidin-4-one

6-Amino-4-pyrimidinol 6-Amino-4(1H)-pyrimidinone

4-Amino-6-hydroxypyrimidine &gt

6-Amino-4-pyrimidinol

4-Hydroxy-6-aminopyrimidine ISO 9001：2015 REACH

1193-22-2

Bases & Related Reagents

Heterocycles

Nucleotides

Heterocycle-Pyrimidine series

Pyridines, Pyrimidines, Purines and Pteredines

PYRIMIDINE

Fluorobenzene

Heterocyclic Compounds

Nucleotides and Nucleosides

Pyrimidines