2-(methylthio)pyrimidine-4,6-diol

Product Name: 2-(methylthio)pyrimidine-4,6-diol
CAS No.: 1979-98-2
Chemical Name: 2-(methylthio)pyrimidine-4,6-diol
Synonyms: S-MTBA;NSC 44557;2-Methylthio-4;1Drug Likeness;6-pyriMidinedione;2-Methylthio-4,6-pyr;S-METHYLTHIOBARBITURIC ACID;2-Methylthiobarbituric acid;2-Mercapto thobarbituric acid;S-MethylthiobarbituricAcid>
CBNumber: CB7345836
Molecular Formula: C5H6N2O2S
Formula Weight: 158.18
MOL File: 1979-98-2.mol

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2-(methylthio)pyrimidine-4,6-diol Property

Melting point:: >300 °C(lit.)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Ethyl Acetate, Ethanol, Methanol
form: Powder
pka: 4.06±0.10(Predicted)
color: White
CAS DataBase Reference: 1979-98-2(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 2
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: M330770
Product name: 2-(Methylthio)-4,6-pyrimidinediol
Packaging: 250mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: A233
Product name: 2-Methylthio-4,6-pyrimidinedione
Packaging: 5g
Price: $14
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0299933
Product name: 2-METHYLTHIO-4,6-PYRIMIDINEDIONE
Purity: 95.00%
Packaging: 5MG
Price: $498.81
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK227500
Product name: 2-Methylthio-4,6-pyrimidinedione
Purity: 98%
Packaging: 100g
Price: $889
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 12252
Product name: 2-(Methylthio)-4,6-pyrimidinediol
Packaging: 1.25g
Price: $1880
Updated: 2021/12/16

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2-(methylthio)pyrimidine-4,6-diol Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

2-(Methylthio)-4,6-pyrimidinediol (cas# 1979-98-2) is a compound useful in organic synthesis.

Synthesis

504-17-6

74-88-4

1979-98-2

Step a: Synthesis of 2-methylthio-pyrimidine-4,6-diol (19a); Iodomethane (32.64 g, 220 mmol) was slowly added dropwise to a suspension of thiobarbituric acid (29 g, 200 mmol) dissolved in ethanol (300 mL) and 2M aqueous sodium hydroxide (110 mL) at room temperature. The reaction mixture was stirred overnight at room temperature, followed by warming to 60 °C and continued stirring for 2 hours. Upon completion of the reaction, ethanol was removed by distillation under reduced pressure, an appropriate amount of water was added and the mixture was cooled in an ice bath for 2 hours. The precipitated solid 4,6-dihydroxy-2-methylmercaptopyrimidine was collected by filtration, washed with ice water and dried to give the product (30 g, 95% yield).

References

[1] Patent: WO2008/95999, 2008, A1. Location in patent: Page/Page column 96
[2] Patent: WO2012/97478, 2012, A1. Location in patent: Page/Page column 58-59

2-(methylthio)pyrimidine-4,6-diol Preparation Products And Raw materials

Raw materials

4,6-Dihydroxypyrimidine 2-Thiobarbituric acid

Preparation Products

4,6-DIMETHOXYPYRIMIDINE-2-SULFONYL CHLORIDE

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2-(methylthio)pyrimidine-4,6-diol Suppliers

Canada 1 China 195 Europe 3 Germany 10 India 12 Italy 1 Japan 7 Slovakia 1 Switzerland 2 United Kingdom 13 United States 40 Global 285

Wuhan Hongde Yuexin Pharmaceutical Technology Co., Ltd

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Shanghai Boyle Chemical Co., Ltd.

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Email: sales@boylechem.com
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J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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3B Pharmachem (Wuhan) International Co.,Ltd.

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Alfa Aesar

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Email: saleschina@alfa-asia.com
Country: China
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TCI (Shanghai) Development Co., Ltd.

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ShangHai DEMO Chemical Co.,Ltd

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Beijing HwrkChemical Technology Co., Ltd

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Energy Chemical

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View Lastest Price from 2-(methylthio)pyrimidine-4,6-diol manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 2-(methylthio)pyrimidine-4,6-diol 1979-98-2
Price: US $100.00-50.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-11-12

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Methylthio-4,6-pyrimidinedione 1979-98-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-25

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Methylthio-4,6-pyrimidinedione 1979-98-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-10

1979-98-2, 2-(methylthio)pyrimidine-4,6-diolRelated Search:

4,6-Dihydroxypyrimidine 3-Mercaptopropionic acid Pyrimidine ISOMETHIOZIN 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL Methimazole Mercaptoacetic acid Succimer Nuclomedone 2-Mercaptoethanol 2-Methylsulfonyl-4,6-dimethoxypyrimidine 4,6-Dimethoxy-2-methylthiopyrimidine 4,6-Dihydroxy-2-methythiopyrimidine 4-Hydroxypyrimidine 4,6-DIMETHOXY-2-METHYLSULFINYLPYRIMIDINE CHEMBRDG-BB 6979119 2-[(4,6-DIMETHOXYPYRIMIDIN-2-YL)THIO]BENZOIC ACID CHEMBRDG-BB 5930279

4-Hydroxy-2-(methylthio)pyrimidin-6(1H)-one, 4,6-Dihydroxy-2-(methylthio)pyrimidine, 2-(Methylsulphanyl)pyrimidine-4,6-diol

6-Hydroxy-2-(methylthio)pyrimidin-4(3H)-one

6-Hydroxy-2-(Methylthio)-4-pyriMidinone

NSC 44557

2-Methylthio-4,6-pyriMidinedione, 95+%

S-MTBA

S-METHYLTHIOBARBITURIC ACID

2-(Methylmercapto)-4,6-pyrimidinediol

4,6-dihydroxy-2-methylmercaprimidine

2-Mercapto thobarbituric acid

4,6-dihydroxyl-2-methylthio-pyrimidine

2-Thiomethyl 4,6-Dihydroxy Pyrimidine

DIHYDROXY-2-METHYLMERCAPTOPYRIMIDINE

2-Methylthiobarbituric acid

4(1H)-PYRIMIDINONE, 6-HYDROXY-2-(METHYLTHIO)-

4,6-DIHYDROXY-2-METHYLTHIOPYRIMIDINE

2-METHYLTHIO-4,6-PYRIMIDINEDIOL

2-Methylthio-4,6-pyrimidinedione

6-Hydroxy-2-(methylthio)pyrimidin-4(3H)-one 95+%

2-(Methylmercapto)-4,6-Pyrimid

2-methylthio-4,6-dihydroxylpyrimidine

2-Methylthiopyrimidin-4,6-diol

4,6-Dihydroxy-2-(methylmercapto)pyrimidine

6-Hydroxy-2-methylthio-4(3H)-pyrimidinone, 97%

4，6-dihydroxy-2-methyl metcapto pyrimidine

4,6-Dihydroxy-2-(methylmercapto)pyrimidine, 4,6-Dihydroxy-2-(methylthio)pyrimidine

2-Methylthio-4,6-pyrimidinedione ,98%

6-Hydroxy-2-(methylthio)pyrimidin-4(1H)-one

6-Hydroxy-2-(methylthio)-4(1H)-pyrimidinone

4-hydroxy-2-(methylthio)-1H-pyrimidin-6-one

4-hydroxy-2-methylsulfanyl-1H-pyrimidin-6-one

2-Methylthio-4,6-pyr

2-Methylthio-4

6-pyriMidinedione

S-MethylthiobarbituricAcid&gt

4(3H)-Pyrimidinone, 6-hydroxy-2-(methylthio)-

1Drug Likeness

2-Methylthio-4,6-pyrimidinedione ISO 9001：2015 REACH

2-Methylthio-5-fluoro-4,6-dihydroxypyrimidine

2-(Methylthio)pyrimidine-4,6-diol

1979-98-2

Building Blocks

Pyrimidines

Heterocyclic Building Blocks

Pyrimidine

Bases & Related Reagents

Nucleotides

Sulfur & Selenium Compounds

Nucleotides and Nucleosides

Pyrimidines

Heterocycle-Pyrimidine series