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4-Hydroxy-6-aminopyrimidine

Product Name
4-Hydroxy-6-aminopyrimidine
CAS No.
1193-22-2
Chemical Name
4-Hydroxy-6-aminopyrimidine
Synonyms
6-AMINOPYRIMIDIN-4-OL;6-AMINOPYRIMIDIN-4(3H)-ONE;4-AMINO-6-HYDROXYPYRIMIDINE;NSC 19868;4-AMino-6-pyriMidinol;6-Amino-4-pyrimidinol;6-Amino-3H-pyrimidin-4-one;6-amino-1H-pyrimidin-4-one;6-Amino-4(1H)-pyrimidinone;6-Amino-4(3H)-pyrimidinone
CBNumber
CB4135450
Molecular Formula
C4H5N3O
Formula Weight
111.1
MOL File
1193-22-2.mol
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4-Hydroxy-6-aminopyrimidine Property

Melting point:
262-264°C
Boiling point:
227.5±43.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO
form 
Solid
pka
10.04±0.40(Predicted)
color 
White
BRN 
112429
InChI
InChI=1S/C4H5N3O/c5-3-1-4(8)7-2-6-3/h1-2H,(H3,5,6,7,8)
InChIKey
HFMLLTVIMFEQRE-UHFFFAOYSA-N
SMILES
C1=NC(N)=CC(=O)N1
CAS DataBase Reference
1193-22-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-41
Safety Statements 
26-36-39
HazardClass 
IRRITANT
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2439
Product name
4-Amino-6-hydroxypyrimidine
Purity
>98.0%(T)
Packaging
1g
Price
$32
Updated
2025/07/31
TCI Chemical
Product number
A2439
Product name
4-Amino-6-hydroxypyrimidine
Purity
>98.0%(T)
Packaging
5g
Price
$137
Updated
2025/07/31
TRC
Product number
A611665
Product name
4-Amino-6-hydroxypyrimidine
Packaging
100mg
Price
$55
Updated
2021/12/16
TRC
Product number
A629075
Product name
6-Aminopyrimidin-4-ol
Packaging
5g
Price
$1100
Updated
2021/12/16
Usbiological
Product number
A1380-24
Product name
6-Aminopyrimidin-4-ol
Packaging
500mg
Price
$425
Updated
2021/12/16
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4-Hydroxy-6-aminopyrimidine Chemical Properties,Usage,Production

Chemical Properties

White Solid

Synthesis

1004-40-6

1193-22-2

Step 2: 2-mercapto-4-amino-6-hydroxypyridine (mass ratio 1:15) was added to 25% ammonia, followed by the addition of activated nickel and titanium dioxide, wherein the molar ratio of 2-mercapto-4-amino-6-hydroxypyridine, activated nickel and titanium dioxide was 1:4:1.5. The mixture was heated to 90°C and the reaction was carried out at reflux for 5 hours. Upon completion of the reaction, the activated nickel and titanium dioxide were removed by thermal filtration. The filtrate was cooled to room temperature and the solid product was precipitated. The solid was washed with 30 mL of water and dried at 40 °C to afford 4-amino-6-hydroxypyrimidine in 98.4% yield.

References

[1] Patent: CN105218554, 2016, A. Location in patent: Paragraph 0023
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 9, p. 1918 - 1929
[3] Patent: EP1406911, 2016, B1. Location in patent: Paragraph 00382; 00383

4-Hydroxy-6-aminopyrimidine Preparation Products And Raw materials

Raw materials

Ethanol 4,6-Dichloropyrimidine RANEY NICKEL Ethyl acetate Hydrochloric acid HYDRAZINE Diisopropyl ether Ammonia

Preparation Products

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4-Hydroxy-6-aminopyrimidine Suppliers

Americas 1 Canada 2 China 145 Europe 4 Germany 3 India 4 Japan 1 The Netherlands 1 United Kingdom 11 United States 26 Global 198
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
CHEMSWORTH
Tel
--
Fax
--
Email
info@chemsworth.com
Country
India
ProdList
6700
Advantage
30
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View Lastest Price from 4-Hydroxy-6-aminopyrimidine manufacturers

Dideu Industries Group Limited
Product
4-Hydroxy-6-aminopyrimidine 1193-22-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-09
Career Henan Chemical Co
Product
4-Hydroxy-6-aminopyrimidine 1193-22-2
Price
US $1.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
500kg
Release date
2019-07-12
Career Henan Chemical Co
Product
4-Hydroxy-6-aminopyrimidine 1193-22-2
Price
US $1.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
500kg
Release date
2019-07-09

1193-22-2, 4-Hydroxy-6-aminopyrimidineRelated Search:

2,5-Diamino-4,6-dihydropyrimidine hemisulfate salt 5-Bromo-4,6-dihydroxypyrimidine 2-Methylthio-4,6-pyrimidinedione 2,4-Diamino-6-hydroxypyrimidine ,98% 4-Hydroxy-6-aminopyrimidine ETRIMFOS 5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE 2-AMINO-4,6-DIHYDROXY-5-NITROPYRIMIDINE 2-Amino-4,6-dihydroxypyrimidine 2,4,5-Triamino-6-chloropyrimidine hydrochloride 4,5-DIAMINO-6-HYDROXYPYRIMIDINE SULFATE 2-Amino-4,6-dimethoxypyrimidine 6-Aminothiouracil 2-Cyanoamino-4,6-dihydroxypyrimidine 4,6-Dihydroxy-2-methylpyrimidine 4,5-DIAMINO-6-HYDROXYPYRIMIDINE HEMISULFATE 2,5-Diamino-4,6-dihydroxy-pyrimidine 4,6-DIHYDROXY-5-NITROPYRIMIDINE

  • 4(3H)-Pyrimidinone, 6-amino-
  • 4-AMINO-6-HYDROXYPYRIMIDINE
  • 6-AMINOPYRIMIDIN-4(3H)-ONE
  • 6-AMINOPYRIMIDIN-4-OL
  • 6-amino-1H-pyrimidin-4-one
  • 4(1H)-Pyrimidinone, 6-amino- (8CI,9CI)
  • 6-Amino-3H-pyrimidin-4-one
  • 4(1H)-Pyrimidinone, 6-amino-
  • 6-AMINO-4-HYDROXYPYRIMIDINE
  • 6-amino-4(1H)-Pyrimidinone (8CI,9CI)
  • 4-Hydroxy-6-aminopyrimidine
  • 4-Amino-6(1H)-oxopyrimidine
  • 6-Amino-3,4-dihydropyrimidine-4-one
  • 6-Amino-4(1H)-pyrimidinone
  • 6-Amino-4(3H)-pyrimidinone
  • 6-Aminopyrimidine-4(3H)-one
  • 4-AMino-6-pyriMidinol
  • NSC 19868
  • 6-AMino-4-pyriMidinol 4-AMino-6-hydroxypyriMidine
  • 6-azanyl-1H-pyrimidin-4-one
  • 6-Amino-4-pyrimidinol 6-Amino-4(1H)-pyrimidinone
  • 4-Amino-6-hydroxypyrimidine &gt
  • 6-Amino-4-pyrimidinol
  • 4-Hydroxy-6-aminopyrimidine ISO 9001：2015 REACH
  • 1193-22-2
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • Heterocycle-Pyrimidine series
  • Pyridines, Pyrimidines, Purines and Pteredines
  • PYRIMIDINE
  • Fluorobenzene
  • Heterocyclic Compounds
  • Nucleotides and Nucleosides
  • Pyrimidines