Description
ChemicalBook > CAS DataBase List > Methyl cyanoacetate

Methyl cyanoacetate

Description
Product Name
Methyl cyanoacetate
CAS No.
105-34-0
Chemical Name
Methyl cyanoacetate
Synonyms
MCYA;usafkf-22;USAF kf-22;25KG,100KG,1T;Methylcyanacetat;2-cyanopropanoate;METHYL CYANOACETATE;MetthylCyanoacetate;methylcyanoethanoate;methyl2-cyanoacetate
CBNumber
CB9485583
Molecular Formula
C4H5NO2
Formula Weight
99.09
MOL File
105-34-0.mol
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Methyl cyanoacetate Property

Melting point:
-13 °C
Boiling point:
204-207 °C(lit.)
Density 
1.123 g/mL at 25 °C(lit.)
vapor density 
3.41 (vs air)
vapor pressure 
0.2 mm Hg ( 20 °C)
refractive index 
n20/D 1.417(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
54g/l
pka
2.75±0.10(Predicted)
form 
Liquid
color 
Clear colorless to very slightly yellow
Water Solubility 
54 g/L (20 ºC)
Sensitive 
Light Sensitive
BRN 
773945
CAS DataBase Reference
105-34-0(CAS DataBase Reference)
NIST Chemistry Reference
Acetic acid, cyano-, methyl ester(105-34-0)
EPA Substance Registry System
Acetic acid, cyano-, methyl ester (105-34-0)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
RIDADR 
3276
WGK Germany 
1
RTECS 
AG4375000
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29269095
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
108421
Product name
Methyl cyanoacetate
Purity
99%
Packaging
25g
Price
$37.3
Updated
2021/03/22
Sigma-Aldrich
Product number
108421
Product name
Methyl cyanoacetate
Purity
99%
Packaging
2kg
Price
$180
Updated
2021/03/22
TCI Chemical
Product number
C0442
Product name
Methyl Cyanoacetate
Purity
>99.0%(GC)
Packaging
25mL
Price
$24
Updated
2021/03/22
TCI Chemical
Product number
C0442
Product name
Methyl Cyanoacetate
Purity
>99.0%(GC)
Packaging
500mL
Price
$53
Updated
2021/03/22
Alfa Aesar
Product number
A15555
Product name
Methyl cyanoacetate, 99%
Packaging
500g
Price
$54.8
Updated
2021/03/22
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Methyl cyanoacetate Chemical Properties,Usage,Production

Description

Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds. It is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate; a compound used in the synthesis of DPP-IV inhibitors for treating type-2 diabetes. In addition, it is an intermediate in the preparation of α-cyanoacrylate, malononitrile, and 1,1-cyclohexanediacetic acid dyes. It is used as UV absorber or stabilizer, intermediate for pharmaceuticals. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds.

Chemical Properties

clear colorless to very slighlty yellow liquid

Uses

pharmaceutical intermediate

Purification Methods

Purify the ester by shaking with 10% Na2CO3 solution, wash well with water, dry with anhydrous Na2SO4, and distil it. [Beilstein 2 H 584, 2 I 253, 2 II 530, 2 III 1628, 2 IV 1889.]

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Methyl cyanoacetate Suppliers

Nanjing Apicci Pharmaceutical Technology Co., Ltd.
Tel
;
Fax
QQ2853590738
Email
2853590738@qq.com;2853579352@qq.com
Country
China
ProdList
404
Advantage
58
Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-83945878-
Fax
022-83945176
Email
export@creasyn.com
Country
China
ProdList
777
Advantage
68
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066-400;021-60496031
Fax
021-55660885
Email
sales@jonln.com;sales@jonln.com
Country
China
ProdList
1999
Advantage
65
Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30159
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 qq:2355568890
Fax
0086-21-50182339
Email
sales@demochem.com; export1@demochem.com
Country
China
ProdList
2582
Advantage
57
Beijing dtftchem Technology Co., Ltd.
Tel
13651141086; 86(10)60275028、60275820
Fax
86 (10) 60270825
Email
dtftchem@sina.com
Country
China
ProdList
3392
Advantage
62
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057-
Fax
0757-86311057
Email
sales.gd@hwrkchemical.com
Country
China
ProdList
17295
Advantage
55
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View Lastest Price from Methyl cyanoacetate manufacturers

Anhui Rencheng Technology Co., Ltd
Product
Methyl cyanoacetate 105-34-0
Price
US $1.00-180.00/KG
Min. Order
0.5KG
Purity
>99%
Supply Ability
20tons
Release date
2021-01-04
Zhuozhou Wenxi import and Export Co., Ltd
Product
Methyl cyanoacetate 105-34-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Methyl cyanoacetate 105-34-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

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