Methyl cyanoacetate
Description- Product Name
- Methyl cyanoacetate
- CAS No.
- 105-34-0
- Chemical Name
- Methyl cyanoacetate
- Synonyms
- Methyl 2-cyanoacetate;2-cyanopropanoate;CYANOACETIC ACID METHYL ESTER;MCYA;usafkf-22;USAF kf-22;25KG,100KG,1T;Methylcyanacetat;METHYL CYANOACETATE;MetthylCyanoacetate
- CBNumber
- CB9485583
- Molecular Formula
- C4H5NO2
- Formula Weight
- 99.09
- MOL File
- 105-34-0.mol
Methyl cyanoacetate Property
- Melting point:
- -13 °C
- Boiling point:
- 204-207 °C(lit.)
- Density
- 1.123 g/mL at 25 °C(lit.)
- vapor density
- 3.41 (vs air)
- vapor pressure
- 0.2 mm Hg ( 20 °C)
- refractive index
- n20/D 1.417(lit.)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 54g/l
- form
- Liquid
- pka
- 2.75±0.10(Predicted)
- color
- Clear colorless to very slightly yellow
- Water Solubility
- 54 g/L (20 ºC)
- Sensitive
- Light Sensitive
- BRN
- 773945
- Dielectric constant
- 29.4（21℃）
- LogP
- -0.47 at 25℃
- CAS DataBase Reference
- 105-34-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Acetic acid, cyano-, methyl ester(105-34-0)
- EPA Substance Registry System
- Acetic acid, cyano-, methyl ester (105-34-0)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 108421
- Product name
- Methyl cyanoacetate
- Purity
- 99%
- Packaging
- 25g
- Price
- $57.4
- Updated
- 2024/03/01
- Product number
- 108421
- Product name
- Methyl cyanoacetate
- Purity
- 99%
- Packaging
- 2kg
- Price
- $209
- Updated
- 2023/06/20
- Product number
- C0442
- Product name
- Methyl Cyanoacetate
- Purity
- >99.0%(GC)
- Packaging
- 25mL
- Price
- $34
- Updated
- 2024/03/01
- Product number
- C0442
- Product name
- Methyl Cyanoacetate
- Purity
- >99.0%(GC)
- Packaging
- 500mL
- Price
- $75
- Updated
- 2024/03/01
- Product number
- A15555
- Product name
- Methyl cyanoacetate, 99%
- Packaging
- 250g
- Price
- $43.2
- Updated
- 2024/03/01
Methyl cyanoacetate Chemical Properties,Usage,Production
Description
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds. It is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate; a compound used in the synthesis of DPP-IV inhibitors for treating type-2 diabetes. In addition, it is an intermediate in the preparation of α-cyanoacrylate, malononitrile, and 1,1-cyclohexanediacetic acid dyes. It is used as UV absorber or stabilizer, intermediate for pharmaceuticals. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds.
Chemical Properties
clear colorless to very slighlty yellow liquid
Uses
pharmaceutical intermediate
Uses
Methyl cyanoacetate is an intermediate in the preparation of α-cyanoacrylate, malononitrile, 1,1-cyclohexanediacetic acid dye. It is used as UV absorber or stabiliser, intermediate for pharmaceuticals. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds.
Definition
ChEBI: Methyl cyanoacetate is an alkyl cyanoacetate ester.
General Description
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Kn?venagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α-cyanocinnamic esters.
Purification Methods
Purify the ester by shaking with 10% Na2CO3 solution, wash well with water, dry with anhydrous Na2SO4, and distil it. [Beilstein 2 H 584, 2 I 253, 2 II 530, 2 III 1628, 2 IV 1889.]
Methyl cyanoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl cyanoacetate manufacturers
- Product
- Methyl cyanoacetate 105-34-0
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-21
- Product
- Methyl Cyanoacetate 105-34-0
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-12
- Product
- Methyl cyanoacetate 105-34-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- >99%
- Supply Ability
- 3000T
- Release date
- 2023-03-20