ChemicalBook > CAS DataBase List > 2-Cyanoacetamide

2-Cyanoacetamide

Product Name
2-Cyanoacetamide
CAS No.
107-91-5
Chemical Name
2-Cyanoacetamide
Synonyms
CYANOACETAMIDE;ACETAMIDE, 2-CYANO-;Cyanacetamide;Kyanacetamid;CYANOACETIC AMIDE;CYAC;2-CAA;usafkf-14;USAF kf-14;Cyanacetamid
CBNumber
CB7852727
Molecular Formula
C3H4N2O
Formula Weight
84.08
MOL File
107-91-5.mol
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2-Cyanoacetamide Property

Melting point:
119-121 °C(lit.)
Boiling point:
154.34°C (rough estimate)
Density 
1,4 g/cm3
refractive index 
1.5110 (estimate)
Flash point:
419 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
cold water: soluble1gm in 6.5ml
pka
-1.27±0.10(Predicted)
form 
Crystalline Powder
color 
White to light cream
Odor
Odorless
Water Solubility 
soluble
Merck 
14,2688
BRN 
878221
CAS DataBase Reference
107-91-5(CAS DataBase Reference)
NIST Chemistry Reference
Acetamide, 2-cyano-(107-91-5)
EPA Substance Registry System
2-Cyanoacetamide (107-91-5)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
22-26-28A
RIDADR 
UN 3439 6.1/PG 3
WGK Germany 
2
RTECS 
AB5950000
TSCA 
Yes
PackingGroup 
III
HS Code 
29159080
HS Code 
29269095
Hazardous Substances Data
107-91-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
108448
Product name
Cyanoacetamide
Purity
99%
Packaging
100g
Price
$62.7
Updated
2024/03/01
Sigma-Aldrich
Product number
108448
Product name
Cyanoacetamide
Purity
99%
Packaging
500g
Price
$201
Updated
2024/03/01
TCI Chemical
Product number
C0437
Product name
2-Cyanoacetamide
Purity
>98.0%(GC)
Packaging
25g
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
C0437
Product name
2-Cyanoacetamide
Purity
>98.0%(GC)
Packaging
500g
Price
$90
Updated
2024/03/01
Alfa Aesar
Product number
A12482
Product name
Cyanoacetamide, 99%
Packaging
100g
Price
$32.1
Updated
2024/03/01
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2-Cyanoacetamide Chemical Properties,Usage,Production

Chemical Properties

White or light yellow needle crystal or powder. Slightly soluble in water, easily soluble in ethanol.

Uses

2-Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H1 receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum. Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence and is useful for the automated analysis of carbohydrates as borate complexes. It can also be used in the synthesis of heterocyclic compounds such as pyrazole, pyridine and pyrimidine derivatives. Moreover, it can also be applied for the spectrophotometric assay of the enzyme activity of cellulose in related host cells.

Preparation

Cyanoacetamide can be prepared from ethyl cyanoacetate and ammonia. Cool the ethyl cyanoacetate to below 200°C, add concentrated ammonia water to react, and the mixture turns from turbid to clear. After cooling in cold water for 20 minutes, a precipitate is precipitated. After filtration and drying, the crude product is obtained, and then the crude product of cyanoacetamide is added. In the boiling ethanol, after dissolving it, add a small amount of activated carbon for decolorization and purification, filter, cool the filtrate to separate out the precipitate, and dry it at 80-100 ℃ to obtain the fine cyanoacetamide.

Definition

2-Cyanoacetamide is an acetic amide with a nitrile functional group. It is a codon of glutamine that directs the placement of glutamine into a polypeptide.

General Description

Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes.

Purification Methods

Crystallise the amide from MeOH/dioxane (6:4), then water and dry it over P2O5 under vacuum. [Beilstein 2 IV 1891.]

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2-Cyanoacetamide Suppliers

Weifang YuKai Chemical Co., Ltd.
Tel
536-0536-8865336 13853655610
Fax
86-536-5310398
Email
sophia@kaihongchem.com
Country
China
ProdList
41
Advantage
55
Jinan Daen Pharmaceutical Technology Co., Ltd
Tel
0531-68657833 15553112864
Fax
-
Email
2098511197@qq.com
Country
China
ProdList
219
Advantage
58
Zibo Chuanggu Chemical Technology Co., Ltd.
Tel
00-15864498288 15864498288
Email
15864498288@163.cn
Country
China
ProdList
43
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
Advantage
62
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View Lastest Price from 2-Cyanoacetamide manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
2-Cyanoacetamide 107-91-5
Price
US $999.00-666.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-14
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Cyanoacetamide 107-91-5
Price
US $1.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-13
ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
Product
2-Cyanoacetamide 107-91-5
Price
US $1.00/g
Min. Order
10g
Purity
99
Supply Ability
20ton
Release date
2022-05-31

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