4'-CHLOROACETANILIDE
- Product Name
- 4'-CHLOROACETANILIDE
- CAS No.
- 539-03-7
- Chemical Name
- 4'-CHLOROACETANILIDE
- Synonyms
- NSC 444;NSC 40563;4-Chloroacetan;PARACETAMOL RC J;4-CHLORACETANILIDE;p-Chloroacetanilid;P-CHLOROACETANILIDE;4-CHLOROACETANILIDE;4'-CHLOROACETANILIDE;ACETAMINOPHENE IMP J
- CBNumber
- CB3377826
- Molecular Formula
- C8H8ClNO
- Formula Weight
- 169.61
- MOL File
- 539-03-7.mol
4'-CHLOROACETANILIDE Property
- Melting point:
- 176-178 °C(lit.)
- Boiling point:
- 333 °C
- Density
- 1,385 g/cm3
- refractive index
- 1.5670 (estimate)
- Flash point:
- 333°C
- storage temp.
- 2-8°C
- solubility
- dioxane: 50 mg/mL hot, clear
- pka
- 14.25±0.70(Predicted)
- form
- Crystalline Powder
- color
- White or grayish-beige
- Water Solubility
- Insoluble in water.
- Merck
- 14,2111
- BRN
- 509638
- CAS DataBase Reference
- 539-03-7(CAS DataBase Reference)
- EPA Substance Registry System
- 4-Chloroacetanilide (539-03-7)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- AE1001000
- TSCA
- Yes
- HS Code
- 29242990
- Hazardous Substances Data
- 539-03-7(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- Y0001945
- Product name
- Paracetamol impurity J
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- Y0001945
- Price
- $152
- Updated
- 2024/03/01
- Product number
- 8.41480
- Product name
- 4-Chloroacetanilide
- Purity
- for synthesis
- Packaging
- 50g
- Price
- $65.3
- Updated
- 2024/03/01
- Product number
- 8.41480
- Product name
- 4-Chloroacetanilide
- Purity
- for synthesis
- Packaging
- 250g
- Price
- $299
- Updated
- 2024/03/01
- Product number
- 158631
- Product name
- 4′-Chloroacetanilide
- Purity
- 97%
- Packaging
- 5g
- Price
- $43.5
- Updated
- 2024/03/01
- Product number
- 1003100
- Product name
- Acetaminophen Related Compound J
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 50mg
- Price
- $1380
- Updated
- 2024/03/01
4'-CHLOROACETANILIDE Chemical Properties,Usage,Production
Chemical Properties
white or greyish-beige crystalline powder
Uses
4'-Chloroacetanilide is used in pharmaceutical preparations, using PGC column. And also used in the synthesis of alprazolam.
Definition
ChEBI: Acetamide substituted on nitrogen by a para-chlorophenyl group.
Synthesis Reference(s)
Tetrahedron, 52, p. 8863, 1996 DOI: 10.1016/0040-4020(96)00433-4
General Description
4′-Chloroacetanilide is the main impurity present in acetaminophen and has been quantitated by new high-performance liquid chromatography method using a mixed-mode reversed-phase/cation exchange stationary phase.
Purification Methods
Crystallise the anilide from EtOH or aqueous EtOH. [Beilstein 12 IV 1178.]
4'-CHLOROACETANILIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4'-CHLOROACETANILIDE manufacturers
- Product
- 4'-CHLOROACETANILIDE 539-03-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-25
- Product
- 4'-CHLOROACETANILIDE 539-03-7
- Price
- US $100.00/bag
- Min. Order
- 1bag
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2023-08-30
- Product
- 4'-CHLOROACETANILIDE 539-03-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-07-04