4-(Hydroxyamino)-4-oxobutanoic acid

Product Name: 4-(Hydroxyamino)-4-oxobutanoic acid
CAS No.: 4743-99-1
Chemical Name: 4-(Hydroxyamino)-4-oxobutanoic acid
Synonyms: Tofacitinib Impurity 208;N-Hydroxysuccinamidic acid;4-(Hydroxyamino)-4-oxobutanoic acid;Butanoic acid, 4-(hydroxyamino)-4-oxo-;3-(Hydroxyaminocarbonyl)propionic acid
CBNumber: CB02174169
Molecular Formula: C4H7NO4
Formula Weight: 133.1
MOL File: 4743-99-1.mol

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4-(Hydroxyamino)-4-oxobutanoic acid Property

Melting point:: 82-86 °C(Solv: acetonitrile (75-05-8))
Density: 1.436±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
pka: 5.28±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Ark Pharm

Product number: AK604764
Product name: 4-(Hydroxyamino)-4-oxobutanoicacid
Purity: 95%
Packaging: 1g
Price: $358
Updated: 2021/12/16

Ambeed

Product number: A160779
Product name: 4-(Hydroxyamino)-4-oxobutanoicacid
Purity: 95%
Packaging: 5g
Price: $918
Updated: 2021/12/16

Ambeed

Product number: A160779
Product name: 4-(Hydroxyamino)-4-oxobutanoicacid
Purity: 95%
Packaging: 100mg
Price: $78
Updated: 2021/12/16

Ambeed

Product number: A160779
Product name: 4-(Hydroxyamino)-4-oxobutanoicacid
Purity: 95%
Packaging: 250mg
Price: $125
Updated: 2021/12/16

Ambeed

Product number: A160779
Product name: 4-(Hydroxyamino)-4-oxobutanoicacid
Purity: 95%
Packaging: 1g
Price: $302
Updated: 2021/12/16

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4-(Hydroxyamino)-4-oxobutanoic acid Chemical Properties,Usage,Production

Preparation

To a refluxing solution of 5.0 gm (0.05 mole) of succinic anhydride in 100 ml of benzene is added a solution of 6.3 gm (0.05 mole) of O-ben- zylhydroxylamine in 20 ml of benzene. As soon as the addition has been completed, the reaction mixture is cooled, and the precipitated product is separated. Upon recrystallization from a benzene-methyl ethyl ketone mixture, 7.6 gm (68.2%) of N-benzyloxysuccinamic acid, m.p. 95-96°C isolated.
A suspension of 4.3 gm (0.0193 mole) of this intermediate and a stron- tium carbonate catalyst containing 5% palladium in methyl ethyl ketone is hydrogenated. Upon working up the reaction mixture, 1.45 gm (56.7%) of succinomonohydroxamic acid, m.p. 95-96°C is isolated.

4-(Hydroxyamino)-4-oxobutanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Hydroxyamino)-4-oxobutanoic acid Suppliers

China 19 Global 19

Bide Pharmatech Ltd.

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4743-99-1, 4-(Hydroxyamino)-4-oxobutanoic acidRelated Search:

Tofacitinib Impurity 19 Tofacitinib impurity T Methyl (4-Methylpiperidin-3-yl)carbaMate 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE BENZYL ETHYL ETHER 4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Tofacitinib Impurity 85 N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 4-Amino-2,6-dichloropyrimidine Malonyl chloride Benzyl chloride 6-AMINO-5(2,2-DIETHOXYETHYL)-4-HYDROXY-2-MERCAPTOPYRIMIDINE 1-Benzyl-4-methyl-piperidin-3-one hydrochloride CYANOACETIC ACID-OSU N-Hydroxysuccinimide Tofacitinib Impurity 29 (3S,4S)-Tofacitinib

3-(Hydroxyaminocarbonyl)propionic acid

4-(Hydroxyamino)-4-oxobutanoic acid

N-Hydroxysuccinamidic acid

Butanoic acid, 4-(hydroxyamino)-4-oxo-

Tofacitinib Impurity 208

4743-99-1