ChemicalBook > CAS DataBase List > 4-(Hydroxyamino)-4-oxobutanoic acid

4-(Hydroxyamino)-4-oxobutanoic acid

Product Name
4-(Hydroxyamino)-4-oxobutanoic acid
CAS No.
4743-99-1
Chemical Name
4-(Hydroxyamino)-4-oxobutanoic acid
Synonyms
Tofacitinib Impurity 208;N-Hydroxysuccinamidic acid;4-(Hydroxyamino)-4-oxobutanoic acid;Butanoic acid, 4-(hydroxyamino)-4-oxo-;3-(Hydroxyaminocarbonyl)propionic acid
CBNumber
CB02174169
Molecular Formula
C4H7NO4
Formula Weight
133.1
MOL File
4743-99-1.mol
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4-(Hydroxyamino)-4-oxobutanoic acid Property

Melting point:
82-86 °C(Solv: acetonitrile (75-05-8))
Density 
1.436±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
pka
5.28±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Ark Pharm
Product number
AK604764
Product name
4-(Hydroxyamino)-4-oxobutanoicacid
Purity
95%
Packaging
1g
Price
$358
Updated
2021/12/16
Ambeed
Product number
A160779
Product name
4-(Hydroxyamino)-4-oxobutanoicacid
Purity
95%
Packaging
100mg
Price
$78
Updated
2021/12/16
Ambeed
Product number
A160779
Product name
4-(Hydroxyamino)-4-oxobutanoicacid
Purity
95%
Packaging
250mg
Price
$125
Updated
2021/12/16
Ambeed
Product number
A160779
Product name
4-(Hydroxyamino)-4-oxobutanoicacid
Purity
95%
Packaging
1g
Price
$302
Updated
2021/12/16
Ambeed
Product number
A160779
Product name
4-(Hydroxyamino)-4-oxobutanoicacid
Purity
95%
Packaging
5g
Price
$918
Updated
2021/12/16
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4-(Hydroxyamino)-4-oxobutanoic acid Chemical Properties,Usage,Production

Preparation

To a refluxing solution of 5.0 gm (0.05 mole) of succinic anhydride in 100 ml of benzene is added a solution of 6.3 gm (0.05 mole) of O-ben- zylhydroxylamine in 20 ml of benzene. As soon as the addition has been completed, the reaction mixture is cooled, and the precipitated product is separated. Upon recrystallization from a benzene-methyl ethyl ketone mixture, 7.6 gm (68.2%) of N-benzyloxysuccinamic acid, m.p. 95-96°C isolated.
A suspension of 4.3 gm (0.0193 mole) of this intermediate and a stron- tium carbonate catalyst containing 5% palladium in methyl ethyl ketone is hydrogenated. Upon working up the reaction mixture, 1.45 gm (56.7%) of succinomonohydroxamic acid, m.p. 95-96°C is isolated.

4-(Hydroxyamino)-4-oxobutanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Hydroxyamino)-4-oxobutanoic acid Suppliers

Bide Pharmatech Ltd.
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China
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60
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Energy Chemical
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View Lastest Price from 4-(Hydroxyamino)-4-oxobutanoic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-(hydroxyamino)-4-oxobutanoic acid 4743-99-1
Price
US $1.00-22.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-08-13