4-(Hydroxyamino)-4-oxobutanoic acid
- Product Name
- 4-(Hydroxyamino)-4-oxobutanoic acid
- CAS No.
- 4743-99-1
- Chemical Name
- 4-(Hydroxyamino)-4-oxobutanoic acid
- Synonyms
- Tofacitinib Impurity 208;N-Hydroxysuccinamidic acid;4-(Hydroxyamino)-4-oxobutanoic acid;Butanoic acid, 4-(hydroxyamino)-4-oxo-;3-(Hydroxyaminocarbonyl)propionic acid
- CBNumber
- CB02174169
- Molecular Formula
- C4H7NO4
- Formula Weight
- 133.1
- MOL File
- 4743-99-1.mol
4-(Hydroxyamino)-4-oxobutanoic acid Property
- Melting point:
- 82-86 °C(Solv: acetonitrile (75-05-8))
- Density
- 1.436±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- pka
- 5.28±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- AK604764
- Product name
- 4-(Hydroxyamino)-4-oxobutanoicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $358
- Updated
- 2021/12/16
- Product number
- A160779
- Product name
- 4-(Hydroxyamino)-4-oxobutanoicacid
- Purity
- 95%
- Packaging
- 100mg
- Price
- $78
- Updated
- 2021/12/16
- Product number
- A160779
- Product name
- 4-(Hydroxyamino)-4-oxobutanoicacid
- Purity
- 95%
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- A160779
- Product name
- 4-(Hydroxyamino)-4-oxobutanoicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $302
- Updated
- 2021/12/16
- Product number
- A160779
- Product name
- 4-(Hydroxyamino)-4-oxobutanoicacid
- Purity
- 95%
- Packaging
- 5g
- Price
- $918
- Updated
- 2021/12/16
4-(Hydroxyamino)-4-oxobutanoic acid Chemical Properties,Usage,Production
Preparation
To a refluxing solution of 5.0 gm (0.05 mole) of succinic anhydride in 100 ml of benzene is added a solution of 6.3 gm (0.05 mole) of O-ben- zylhydroxylamine in 20 ml of benzene. As soon as the addition has been completed, the reaction mixture is cooled, and the precipitated product is separated. Upon recrystallization from a benzene-methyl ethyl ketone mixture, 7.6 gm (68.2%) of N-benzyloxysuccinamic acid, m.p. 95-96°C isolated.
A suspension of 4.3 gm (0.0193 mole) of this intermediate and a stron- tium carbonate catalyst containing 5% palladium in methyl ethyl ketone is hydrogenated. Upon working up the reaction mixture, 1.45 gm (56.7%) of succinomonohydroxamic acid, m.p. 95-96°C is isolated.
4-(Hydroxyamino)-4-oxobutanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(Hydroxyamino)-4-oxobutanoic acid manufacturers
- Product
- 4-(hydroxyamino)-4-oxobutanoic acid 4743-99-1
- Price
- US $1.00-22.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100000KG
- Release date
- 2024-08-13