ChemicalBook > CAS DataBase List > 4-Chloro-2,6-diaminopyrimidine

4-Chloro-2,6-diaminopyrimidine

Product Name
4-Chloro-2,6-diaminopyrimidine
CAS No.
156-83-2
Chemical Name
4-Chloro-2,6-diaminopyrimidine
Synonyms
2,4-DIAMINO-6-CHLOROPYRIMIDINE;6-CHLORO-PYRIMIDINE-2,4-DIAMINE;NSC 8818;JACS-156-83-2;TIMTEC-BB SBB004123;4-Chloro-2,6-diamino;DiaMino-6-chloropyriMid;Minoxidil EP Impurity B;Minoxidil EP Impurity 3;oro-2,6-diaminopyrimidine
CBNumber
CB9194300
Molecular Formula
C4H5ClN4
Formula Weight
144.56
MOL File
156-83-2.mol
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4-Chloro-2,6-diaminopyrimidine Property

Melting point:
199-202 °C(lit.)
Boiling point:
199-202 °C
Density 
1.3966 (rough estimate)
vapor pressure 
0.0±1.1 mmHg at 25°C
refractive index 
1.702
Flash point:
218.9±29.6 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
slightly soluble
pka
3.66±0.10(Predicted)
form 
Solid
color 
White to Pale Yellow
Water Solubility 
slightly soluble
BRN 
118455
InChI
InChI=1S/C4H5ClN4/c5-2-1-3(6)9-4(7)8-2/h1H,(H4,6,7,8,9)
InChIKey
QJIUMVUZDYPQRT-UHFFFAOYSA-N
SMILES
C1(N)=NC(Cl)=CC(N)=N1
CAS DataBase Reference
156-83-2(CAS DataBase Reference)
NIST Chemistry Reference
Pyrimidine, 6-chloro-2,4-diamino-(156-83-2)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-24/25
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C33204
Product name
2,6-Diamino-4-chloropyrimidine
Purity
98%
Packaging
5g
Price
$53.3
Updated
2024/03/01
Sigma-Aldrich
Product number
C33204
Product name
2,6-Diamino-4-chloropyrimidine
Purity
98%
Packaging
25g
Price
$166
Updated
2024/03/01
TCI Chemical
Product number
C0811
Product name
6-Chloro-2,4-diaminopyrimidine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$58
Updated
2024/03/01
Alfa Aesar
Product number
A17780
Product name
2,4-Diamino-6-chloropyrimidine, 98%
Packaging
25g
Price
$0
Updated
2021/12/16
Alfa Aesar
Product number
A17780
Product name
2,4-Diamino-6-chloropyrimidine, 98%
Packaging
5g
Price
$38.8
Updated
2021/12/16
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4-Chloro-2,6-diaminopyrimidine Chemical Properties,Usage,Production

Chemical Properties

White Cyrstalline Solid

Uses

Melamine and Related Compounds in Dog Food Using GC-MS

Definition

ChEBI: 6-chloro-2,4-pyrimidinediamine (4-Chloro-2,6-diaminopyrimidine) is a member of pyrimidines and an organohalogen compound.

Synthesis

2,4-Diamino-6-hydroxypyrimidine (1.00 g, 7.93 mmol) was added to POCl3 (9 mL) and stirred at 97 ℃ for 17 h. The reaction solution was added to ice water slowly and then stirred at 90 C for 1 h. The pH of this solution was adjusted to 8 with NaOH, and then it was extracted with EtOAC (150 mL 3). The combined organic layers were dried with Na2SO4, filtered, and concentrated to give white solid 4-Chloro-2,6-diaminopyrimidine 0.97 g, yielding 85%.
4-Chloro-2,6-diaminopyrimidine

Purification Methods

It recrystallises from boiling H2O (charcoal) as needles; it also crystallises from Me2CO. [Büttner Chem Ber 36 2232 1903, Roth J Am Chem Soc 72 1914 1950, UV: Brown & Jacobsen J Chem Soc 3172 1962, Beilstein 24 H 318, 25 III/IV 2788.]

4-Chloro-2,6-diaminopyrimidine Preparation Products And Raw materials

Raw materials

Phosphorus oxychloride Sodium Methoxide Guanidine nitrate Methyl cyanoacetate

Preparation Products

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4-Chloro-2,6-diaminopyrimidine Suppliers

Americas 1 Belgium 3 Canada 3 China 479 Czech Republic 1 Europe 5 France 1 Germany 7 India 48 Italy 1 Japan 3 Jordan 1 Russia 1 Slovakia 1 South Korea 2 Switzerland 3 The Netherlands 2 Ukraine 1 United Kingdom 19 United States 67 Global 649
Shandong Look Chemical Co. LTD
Tel
156-89709505 15689709505
Email
sales01@sdlookchem.com
Country
China
ProdList
11
Advantage
58
East Star Biotech (Suzhou) Co., Ltd.
Tel
0512-62620298 18114352668
Email
marketing@eaststarbio.com
Country
China
ProdList
31
Advantage
58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
13396369453 QQ3007939906 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
872
Advantage
58
Shandong Zhishang Chemical Co. LTD
Tel
15689709505 15508639737
Email
2138533552@qq.com
Country
China
ProdList
53
Advantage
58
Jinan Sanyuan Chemical Co. LTD
Tel
13335164090
Fax
0531-58585914
Email
1660423085@qq.com
Country
China
ProdList
413
Advantage
58
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42957
Advantage
64
Shanghai Yanze Chemical Co., Ltd.
Tel
021-13773155751 19975051755
Email
260924549@qq.com
Country
China
ProdList
8929
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58
Changzhou Gangtong Chemical Co., Ltd
Tel
13506120961
Email
sales@gangtongchem.com
Country
China
ProdList
45
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
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View Lastest Price from 4-Chloro-2,6-diaminopyrimidine manufacturers

Chongqing Soarwin Technology Co., Ltd
Product
4-Chloro-2,6-diaminopyrimidine 156-83-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
20 tons
Release date
2025-04-09
Jinan Finer Chemical Co., Ltd
Product
4-Chloro-2,6-diaminopyrimidine 156-83-2
Price
US $5.00/kg
Min. Order
1kg
Purity
≥99%
Supply Ability
1000mt/year
Release date
2023-12-06
Hebei Mujin Biotechnology Co.,Ltd
Product
4-Chloro-2,6-diaminopyrimidine 156-83-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-01

156-83-2, 4-Chloro-2,6-diaminopyrimidineRelated Search:

Iminodiacetonitrile 1,3-Diaminoguanidine monohydrochloride 4,6-Dihydroxypyrimidine Iminodiacetic acid Diaminomaleonitrile 4-Amino-6-chloropyrimidine 2,4-Dichloropyrimidine HYDRAZINE 4,4'-Methylenedianiline Difluorochloromethane 4-Chloro-2,6-Diaminopyrimidine-N-Oxide,6-Chloro-2,4-diaminopyrimidine-N-oxide 4-CHLORO-6-MORPHOLIN-4-YLPYRIMIDIN-2-AMINE 6-CHLORO-N4,N4-DIETHYLPYRIMIDINE-2,4-DIAMINE 4-CHLORO-5,6-DIAMINOPYRIMIDINE,6-Chloro-4,5-diaminopyrimidine 2-CHLORO-4,5-DIAMINOPYRIMIDINE Minoxidil 4-Chloropyrimidine 6-CHLORO-N4,N4-DIPROPYL-2,4-PYRIMIDINEDIAMINE

  • 4-DiaMino-6-chloropyriMidine
  • NSC 8818
  • DIAMINO-6-CHLOROPYRIMIDINE, 2,4-(SH)
  • 2,4-DIAMINO-6-CHLOROPYRIMIDINE FOR SYNTH
  • 2,6-DiaMino-4-chloropyriMidine 98%
  • DiaMino-6-chloropyriMid
  • 2,4-Diamino-6-chloropyrimidine,98%
  • 4-Chloro-2,6-diaminopyrimidine, 4-Chloro-2,6-diamino-1,3-diazine
  • 2,4-Diamino-6-chloropyrimidine for synthesis
  • 2-AMINO-6-CHLORO-4-PYRIMIDINYLAMINE
  • Pyrimidine,2,4-diamino-6-chloro-
  • 2,4-Diamino-6-Chloro Pyridine
  • 2,4-DIAMINO-6-CHLOROPYRIMIDINE
  • 2,6-DIAMINO-4-CHLORO PYRIMIDINE
  • 4-Chloro-2-6-Diaminopyrimide
  • 2,4-Diamino-6-chloropyrimidine, 99+%
  • 2,4-Pyrimidinediamine, 6-chloro- (9CI)
  • 6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine
  • 2,4-DIAMINO-6-CHLOROPYRIMIDINE/ MINOXIDIL
  • 4-CHLORO-2,6-DIAMINOPYRIMIDINE 98%
  • 4-CHLORO-2,6-DIAMINOPYRIMIDINE (2,4-DIAMINO-6-CHLOROPYRIMIDINE)
  • 4-Chloropyrimidine-2,6-diamine
  • 4-Chloro-2,6-diaminopyrimidine,98%
  • 4-Chloro-2,6-diaminopyrimidine ,99%
  • 2,6-Diamino-4-chloropyrimidine,4-Chloro-2,6-diaminopyrimidine
  • 4-Chloro-2,6-diamino
  • 2,6-Diamino-4-chloropyrimidine ,98%
  • 2,6-Diamino-4-chloropyrimidine (Internal Standard)
  • 156-83-2, MFCD00006097, 4-Chloro-2,6-diaminopyrimidine
  • JACS-156-83-2
  • 4-CHLORO-2,6-DIAMINOPYRIMIDINE
  • 6-CHLORO-PYRIMIDINE-2,4-DIAMINE
  • 6-CHLORO-PYRIMIDINE-2,4-DIYLDIAMINE
  • 6-CHLORO-2,4-DIAMINOPYRIMIDINE
  • TIMTEC-BB SBB004123
  • 2,4-Pyrimidinediamine, 6-chloro-
  • 2,4-Pyrimidinediamine,6-chloro-
  • 4-Chloro-2,6-pyrimidinediamine
  • 6-Chlor-2,4-diaminopyrimidin(4-2,6)
  • 6-Chloro-2,4-pyrimidinediamine
  • 6-chloro-4-pyrimidinediamine
  • Minoxidil EP Impurity B
  • 2,6-Diamini-4-chloro pyrimidine
  • 2,4-Diamino-6-chloropyramidine
  • Minoxidil Impurity 2(Minoxidil EP Impurity B）
  • 6-Chloro-2,4-diaminopyrimidine &gt
  • 2,6-Diamino-4-chloropyrimidine (Internal Standard)@1000 μg/mL in Pyridine
  • 156-83-2, MFCD00006097, 4-ChL
  • oro-2,6-diaminopyrimidine
  • 2,4-Diamino-6-chloropyrimidine (2,4-DACP)
  • DIAMINO-6-CHLOROPYRIMIDINE, 2,4-
  • C12193500 2,6-Diamino-4-chloropyrimidine
  • Minoxidil EP Impurity 3
  • 156-83-2
  • C4H5CIN4
  • HETERO CHLORIDE
  • Pyrimidines
  • Heterocyclic Building Blocks