4-Chloro-2,6-diaminopyrimidine

Product Name: 4-Chloro-2,6-diaminopyrimidine
CAS No.: 156-83-2
Chemical Name: 4-Chloro-2,6-diaminopyrimidine
Synonyms: 2,4-DIAMINO-6-CHLOROPYRIMIDINE;6-CHLORO-PYRIMIDINE-2,4-DIAMINE;NSC 8818;JACS-156-83-2;TIMTEC-BB SBB004123;4-Chloro-2,6-diamino;DiaMino-6-chloropyriMid;Minoxidil EP Impurity B;Minoxidil EP Impurity 3;oro-2,6-diaminopyrimidine
CBNumber: CB9194300
Molecular Formula: C4H5ClN4
Formula Weight: 144.56
MOL File: 156-83-2.mol

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4-Chloro-2,6-diaminopyrimidine Property

Melting point:: 199-202 °C(lit.)
Boiling point:: 199-202 °C
Density: 1.3966 (rough estimate)
vapor pressure: 0.0±1.1 mmHg at 25°C
refractive index: 1.702
Flash point:: 218.9±29.6 °C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: slightly soluble
pka: 3.66±0.10(Predicted)
form: Solid
color: White to Pale Yellow
Water Solubility: slightly soluble
BRN: 118455
InChI: InChI=1S/C4H5ClN4/c5-2-1-3(6)9-4(7)8-2/h1H,(H4,6,7,8,9)
InChIKey: QJIUMVUZDYPQRT-UHFFFAOYSA-N
SMILES: C1(N)=NC(Cl)=CC(N)=N1
CAS DataBase Reference: 156-83-2(CAS DataBase Reference)
NIST Chemistry Reference: Pyrimidine, 6-chloro-2,4-diamino-(156-83-2)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-24/25
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29335995

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C33204
Product name: 2,6-Diamino-4-chloropyrimidine
Purity: 98%
Packaging: 5g
Price: $53.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: C33204
Product name: 2,6-Diamino-4-chloropyrimidine
Purity: 98%
Packaging: 25g
Price: $166
Updated: 2024/03/01

TCI Chemical

Product number: C0811
Product name: 6-Chloro-2,4-diaminopyrimidine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $58
Updated: 2024/03/01

Alfa Aesar

Product number: A17780
Product name: 2,4-Diamino-6-chloropyrimidine, 98%
Packaging: 25g
Price: $0
Updated: 2021/12/16

Alfa Aesar

Product number: A17780
Product name: 2,4-Diamino-6-chloropyrimidine, 98%
Packaging: 5g
Price: $38.8
Updated: 2021/12/16

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4-Chloro-2,6-diaminopyrimidine Chemical Properties,Usage,Production

Chemical Properties

White Cyrstalline Solid

Uses

Definition

ChEBI: 6-chloro-2,4-pyrimidinediamine (4-Chloro-2,6-diaminopyrimidine) is a member of pyrimidines and an organohalogen compound.

Synthesis

2,4-Diamino-6-hydroxypyrimidine (1.00 g, 7.93 mmol) was added to POCl3 (9 mL) and stirred at 97 ℃ for 17 h. The reaction solution was added to ice water slowly and then stirred at 90 C for 1 h. The pH of this solution was adjusted to 8 with NaOH, and then it was extracted with EtOAC (150 mL 3). The combined organic layers were dried with Na2SO4, filtered, and concentrated to give white solid 4-Chloro-2,6-diaminopyrimidine 0.97 g, yielding 85%.

Purification Methods

It recrystallises from boiling H2O (charcoal) as needles; it also crystallises from Me2CO. [Büttner Chem Ber 36 2232 1903, Roth J Am Chem Soc 72 1914 1950, UV: Brown & Jacobsen J Chem Soc 3172 1962, Beilstein 24 H 318, 25 III/IV 2788.]

4-Chloro-2,6-diaminopyrimidine Preparation Products And Raw materials

Raw materials

Phosphorus oxychloride Sodium Methoxide Guanidine nitrate Methyl cyanoacetate

Preparation Products

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4-Chloro-2,6-diaminopyrimidine Suppliers

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View Lastest Price from 4-Chloro-2,6-diaminopyrimidine manufacturers

Jinan Finer Chemical Co., Ltd

Product: 4-Chloro-2,6-diaminopyrimidine 156-83-2
Price: US $5.00/kg
Min. Order: 1kg
Purity: ≥99%
Supply Ability: 1000mt/year
Release date: 2023-12-06

hebei hongtan Biotechnology Co., Ltd

Product: 4-Chloro-2,6-diaminopyrimidine 156-83-2
Price: US $20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000kg
Release date: 2024-05-14

Hebei Chuanghai Biotechnology Co,.LTD

Product: 4-Chloro-2,6-diaminopyrimidine 156-83-2
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-20

156-83-2, 4-Chloro-2,6-diaminopyrimidineRelated Search:

Iminodiacetonitrile 1,3-Diaminoguanidine monohydrochloride 4,6-Dihydroxypyrimidine Iminodiacetic acid Diaminomaleonitrile 4-Amino-6-chloropyrimidine 2,4-Dichloropyrimidine HYDRAZINE 4,4'-Methylenedianiline Difluorochloromethane 4-Chloro-2,6-Diaminopyrimidine-N-Oxide,6-Chloro-2,4-diaminopyrimidine-N-oxide 4-CHLORO-6-MORPHOLIN-4-YLPYRIMIDIN-2-AMINE 6-CHLORO-N4,N4-DIETHYLPYRIMIDINE-2,4-DIAMINE 4-CHLORO-5,6-DIAMINOPYRIMIDINE,6-Chloro-4,5-diaminopyrimidine 2-CHLORO-4,5-DIAMINOPYRIMIDINE 4-Chloropyrimidine Minoxidil 6-CHLORO-N4,N4-DIPROPYL-2,4-PYRIMIDINEDIAMINE

4-DiaMino-6-chloropyriMidine

NSC 8818

DIAMINO-6-CHLOROPYRIMIDINE, 2,4-(SH)

2,4-DIAMINO-6-CHLOROPYRIMIDINE FOR SYNTH

2,6-DiaMino-4-chloropyriMidine 98%

DiaMino-6-chloropyriMid

2,4-Diamino-6-chloropyrimidine,98%

4-Chloro-2,6-diaminopyrimidine, 4-Chloro-2,6-diamino-1,3-diazine

2,4-Diamino-6-chloropyrimidine for synthesis

2-AMINO-6-CHLORO-4-PYRIMIDINYLAMINE

Pyrimidine,2,4-diamino-6-chloro-

2,4-Diamino-6-Chloro Pyridine

2,4-DIAMINO-6-CHLOROPYRIMIDINE

2,6-DIAMINO-4-CHLORO PYRIMIDINE

4-Chloro-2-6-Diaminopyrimide

2,4-Diamino-6-chloropyrimidine, 99+%

2,4-Pyrimidinediamine, 6-chloro- (9CI)

6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine

2,4-DIAMINO-6-CHLOROPYRIMIDINE/ MINOXIDIL

4-CHLORO-2,6-DIAMINOPYRIMIDINE 98%

4-CHLORO-2,6-DIAMINOPYRIMIDINE (2,4-DIAMINO-6-CHLOROPYRIMIDINE)

4-Chloropyrimidine-2,6-diamine

4-Chloro-2,6-diaminopyrimidine,98%

4-Chloro-2,6-diaminopyrimidine ,99%

2,6-Diamino-4-chloropyrimidine,4-Chloro-2,6-diaminopyrimidine

4-Chloro-2,6-diamino

2,6-Diamino-4-chloropyrimidine ,98%

2,6-Diamino-4-chloropyrimidine (Internal Standard)

156-83-2, MFCD00006097, 4-Chloro-2,6-diaminopyrimidine

JACS-156-83-2

4-CHLORO-2,6-DIAMINOPYRIMIDINE

6-CHLORO-PYRIMIDINE-2,4-DIAMINE

6-CHLORO-PYRIMIDINE-2,4-DIYLDIAMINE

6-CHLORO-2,4-DIAMINOPYRIMIDINE

TIMTEC-BB SBB004123

2,4-Pyrimidinediamine, 6-chloro-

2,4-Pyrimidinediamine,6-chloro-

4-Chloro-2,6-pyrimidinediamine

6-Chlor-2,4-diaminopyrimidin(4-2,6)

6-Chloro-2,4-pyrimidinediamine

6-chloro-4-pyrimidinediamine

Minoxidil EP Impurity B

2,6-Diamini-4-chloro pyrimidine

2,4-Diamino-6-chloropyramidine

Minoxidil Impurity 2(Minoxidil EP Impurity B）

6-Chloro-2,4-diaminopyrimidine &gt

2,6-Diamino-4-chloropyrimidine (Internal Standard)@1000 μg/mL in Pyridine

156-83-2, MFCD00006097, 4-ChL

oro-2,6-diaminopyrimidine

2,4-Diamino-6-chloropyrimidine (2,4-DACP)

DIAMINO-6-CHLOROPYRIMIDINE, 2,4-

C12193500 2,6-Diamino-4-chloropyrimidine

Minoxidil EP Impurity 3

156-83-2

C4H5CIN4

HETERO CHLORIDE

Pyrimidines

Heterocyclic Building Blocks