ChemicalBook > CAS DataBase List > 2,4-Diamino-6-hydroxypyrimidine

2,4-Diamino-6-hydroxypyrimidine

Product Name
2,4-Diamino-6-hydroxypyrimidine
CAS No.
56-06-4
Chemical Name
2,4-Diamino-6-hydroxypyrimidine
Synonyms
1956-6-4;2,6-DIAMINOPYRIMIDIN-4-OL;DAHP;2,6-Diaminopyrimidin-4(1H)-one;2,6-DIAMINO-4-PYRIMIDINOL;2,6-diamino-1H-pyrimidin-4-one;2,6-DIAMINO-4-HYDROXYPYRIMIDINE;4(3H)-pyrimidinone, 2,6-diamino-;NSC 9302;NSC18522
CBNumber
CB0174912
Molecular Formula
C4H6N4O
Formula Weight
126.12
MOL File
56-06-4.mol
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2,4-Diamino-6-hydroxypyrimidine Property

Melting point:
285-286 °C (dec.) (lit.)
Boiling point:
234.22°C (rough estimate)
Density 
1.3659 (rough estimate)
refractive index 
1.7990 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
10.61±0.50(Predicted)
form 
Fine Crystalline Powder
color 
White to cream
Sensitive 
Light Sensitive
Merck 
14,2981
BRN 
125006
InChIKey
SWELIMKTDYHAOY-UHFFFAOYSA-N
CAS DataBase Reference
56-06-4(CAS DataBase Reference)
NIST Chemistry Reference
4(1H)-pyrimidinone, 2,6-diamino-(56-06-4)
EPA Substance Registry System
2,6-Diamino-4(1H)-pyrimidinone (56-06-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D1321
Product name
2,4-Diamino-6-hydroxypyrimidine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$76
Updated
2024/03/01
Alfa Aesar
Product number
B21240
Product name
2,4-Diamino-6-hydroxypyrimidine, 96%
Packaging
25g
Price
$28.65
Updated
2024/03/01
Alfa Aesar
Product number
B21240
Product name
2,4-Diamino-6-hydroxypyrimidine, 96%
Packaging
100g
Price
$68.65
Updated
2024/03/01
Cayman Chemical
Product number
81260
Product name
2,4-Diamino-6-hydroxypyrimidine
Purity
≥98%
Packaging
1g
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
81260
Product name
2,4-Diamino-6-hydroxypyrimidine
Purity
≥98%
Packaging
5g
Price
$50
Updated
2024/03/01
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2,4-Diamino-6-hydroxypyrimidine Chemical Properties,Usage,Production

Description

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.

Chemical Properties

White Solid

Uses

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical]

Uses

It stands at the beginning of the enzyme-catalyzed cascade that starts with this seven-carbon carbohydrate and ends with the aromatic amino acids phenylalanine, tyrosine, and tryptophan

Uses

2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.

storage

+4°C

Purification Methods

It recrystallises from H2O. [Beilstein 25 III/IV 3642.]

2,4-Diamino-6-hydroxypyrimidine Preparation Products And Raw materials

Raw materials

Guanidine nitrate Methyl cyanoacetate

Preparation Products

2,4-DIAMINO-6-MERCAPTOPYRIMIDINE 2,6-DIAMINO-4-METHOXY PYRIMIDINE
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View Lastest Price from 2,4-Diamino-6-hydroxypyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,4-Diamino-6-hydroxypyrimidine 56-06-4
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50ton
Release date
2020-05-19
Anhui Ruihan Technology Co., Ltd
Product
2,4-Diamino-6-hydroxypyrimidine 56-06-4
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000t/year
Release date
2023-09-08
Shaanxi Didu New Materials Co. Ltd
Product
2,4-Diamino-6-hydroxypyrimidine 56-06-4
Price
US $1.50/g
Min. Order
1g
Purity
99.0% Min
Supply Ability
100 Tons
Release date
2022-09-20

56-06-4, 2,4-Diamino-6-hydroxypyrimidineRelated Search:

Triclosan 1,3-Dihydroxyacetone 4,4'-Methylenedianiline Iminodiacetic acid 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL 4-Hydroxy-6-aminopyrimidine 1-Hydroxyethylidene-1,1-diphosphonic acid 1,3-Diaminoguanidine monohydrochloride Iminodiacetonitrile 4-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester Methyl 4-(4-oxobutyl)benzoate N-[4-[3-(2,6-DiaMino-1,4-dihydro-4-oxo-5-pyriMidinyl)-3-oxopropyl]benzoyl]-L-glutaMic Acid 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid 3-Buten-1-ol PeMetrexed IMpurity D PeMetrexed EP IMpurity C Methyl 4-bromobenzoate Benzoic acid, 4-(1-methyl-3-oxopropyl)-, methyl ester (9CI)

  • TIMTEC-BB SBB004252
  • 2,4-DIAMINOPYRIMIDIN-6-OL
  • 2,4-DIAMINO-6-HYDROXYPYRIMIDINE
  • 2,4-DIAMINO-6-PYRIMIDINOL
  • 2,4-DIAMINO-6(1H)-PYRIMIDINONE
  • 2,6-DIAMINO-4-PYRIMIDINOL
  • 2,6-DIAMINO-4-PYRIMIDINONE
  • 2,6-DIAMINOPYRIMIDIN-4-OL
  • 2,6-DIAMINO-4(1H)-PYRIMIDINONE
  • 2,6-DIAMINO-4-HYDROXYPYRIMIDINE
  • AURORA KA-376
  • DAHP
  • AKOS MSC-0109
  • 2,6-Diamino-4-Hydroxyprimidine
  • 2,6-diamino-1H-pyrimidin-4-one
  • 2-4-DIAMINO6HYDROXY PYRIMID
  • 2,4- two-6- aMinohydroxy pyriMidine
  • 2,4-DiaMino-6-hydroxypyriMidine 96%
  • 2,4-DiaMino-6-hydroxypyriMidine, 97+%
  • 3-methylidene-1,5-benzodioxepine
  • Pemetrexed Impurity 16
  • 4(3H)-pyrimidinone, 2,6-diamino-
  • InChI=1/C4H6N4O/c5-2-1-3(9)8-4(6)7-2/h1H,(H5,5,6,7,8,9
  • 1956-6-4
  • 2,4-Diamino-6-hydroxypyrimidiine
  • 4(1H)-Pyrimidinone, 2,6-diamino- (8CI,9CI)
  • 2,6-Diaminopyrimidin-4-one
  • 6-Aminoisocytosine
  • NSC 44914
  • NSC 680818
  • NSC 9302
  • 2,4-Diamino-6-hydroxy
  • 2,4-diaminohypoxanthine
  • 2,6-Diamino-1H-pyrimidin-4-on
  • 2,4-Diamino-6. -Hydroxypyimidine
  • 2,6-DIAMINO-3H-PYRIMIDIN-4-ONE
  • 4(1H)-Pyrimidinone, 2,6-diamino
  • 2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol, 2,6-Diamino-4-pyrimidinone
  • 2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol
  • 2,4-Diamino-6-pyrimidinone
  • 2,6-Diamino-3,4-dihydropyrimidine-4-one
  • 2,6-Diamino-4(3H)-pyrimidinone
  • 2,6-Diaminopyrimidin-4(1H)-one
  • 2,4-Diamino-6-hydroxypyrimidine,2,4-Diamino-6-hydroxypyrimidine, 2,6-Diamino-4-pyrimidinol, 2,6-Diamino-4-pyrimidinone
  • 4-DiaMino-6-hydroxypyriMidine
  • 2,4-Diamino-6-hydroxypyrimidine,96%
  • 2,4-DIAMINO-6-HYDROXYPYRIDIMIDINE
  • 6-Hydroxy-2,4-diaminopyrimidine
  • 2,4-Diamino-6-hydroxypyrimidine &gt
  • 2,4-Diamino-6-hydroxypyrimidine ISO 9001：2015 REACH
  • 2,4-Diamino-6-hydroxypyrimidine,56-06-4
  • NSC 18522
  • NSC18522
  • NSC-18522
  • Minoxidil Impurity 19
  • Venadaparib Impurity 45
  • 2,4-Diamino-6-hydroxypyrimidine(98.60%)
  • 56-06-4